Diabetes and lower extremity arterial disease

ESC CardioMed ◽  
2018 ◽  
pp. 944-946
Author(s):  
Lucia Mazzolai ◽  
Victor Aboyans ◽  
Marianne Brodmann

The risk of lower extremity arterial disease (LEAD) is markedly increased among patients with diabetes and ischaemic event rates are more frequent in LEAD populations with than among those without diabetes. A multidisciplinary approach to LEAD diabetic patients is essential. Proper diagnosis and management is crucial in this selected group of patients to reduce cardiovascular burden and decrease limb adverse events. This chapter reviews the clinical implications of LEAD in diabetic patients, diagnostic strategies, and management.

2017 ◽  
Vol 36 (3) ◽  
pp. 270-277 ◽  
Author(s):  
Rudresh Hiremath ◽  
Goutham Gowda ◽  
Jebin Ibrahim ◽  
Harish T Reddy ◽  
Haritha Chodiboina ◽  
...  

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Mathilde Nativel ◽  
Louis Potier ◽  
Laure Alexandre ◽  
Laurence Baillet-Blanco ◽  
Eric Ducasse ◽  
...  

2020 ◽  
Vol 26 ◽  
pp. 107602962091597
Author(s):  
Kehua Wang ◽  
Ying Li ◽  
Fengli Gao ◽  
Haiwen Gong ◽  
Xueru Li ◽  
...  

To evaluate the efficacy and safety of TurboHawk plaque rotation system combined with drug-coated balloon in treating lower extremity arterial disease (LEAD) of diabetes patients, a total of 145 diabetic patients with LEAD from March 2015 to September 2016 were recruited in our study. Lower extremity arterial disease was diagnosed by ultrasound and CT angiography (CTA). According to the surgical method, 65 cases underwent TurboHawk plaque rotation combined with drug-coated balloon (group A), 80 cases underwent simple drug-coated balloon expansion (group B). The characteristics of lesion, function test, ankle-brachial index (ABI), and postoperative complications were analyzed. All the patients were followed up at 1, 3, 6, 12, and 24 months after operation. At baseline, there was no difference in all the characteristics between the 2 groups. The early postoperation minimum lumen diameter (MLD), lumen stenosis rate, and ABI in 2 groups both improved. As the follow-up time increased, patients in group A had significantly higher MLD and ABL value, as well as lower level of lumen stenosis rate, restenosis rate, late lumen loss, and target lesion revascularization (all P < .05). Accordingly, functional testing revealed the 6-minute walk distance, 6-minute claudication distance, resting ABI, and post-exercise ABI in group A were significantly higher than those in group B (all P < .05). Besides, major graft reintervention (4.62% vs 11.25%) and major adverse limb events (6.15% vs 12.5%) in group A occurred less frequently than group B (all P < .05). In conclusion, the long-term effect of the combined approach was better than only drug-coated balloon in LEAD in Chinese diabetes patients.


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