Liver, pancreatic, and biliary surgery

2021 ◽  
pp. 405-430

This chapter outlines the assessment of a patient who presents with jaundice. The management of the common benign conditions affecting the liver, pancreas and biliary system, such as gallstones, common bile duct stones, acute and chronic pancreatitis, benign liver lesions, liver cirrhosis and portal hypertension, are detailed. It also describes the management of the relevant malignancies; pancreatic cancer, hepatocellular cancer, cholangiocarcinoma, gallbladder cancer and colorectal liver metastases.

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1244
Author(s):  
Sonja Schwarz ◽  
Dirk-André Clevert ◽  
Michael Ingrisch ◽  
Thomas Geyer ◽  
Vincent Schwarze ◽  
...  

Background: To evaluate the diagnostic accuracy of quantitative perfusion parameters in contrast-enhanced ultrasound to differentiate malignant from benign liver lesions. Methods: In this retrospective study 134 patients with a total of 139 focal liver lesions were included who underwent contrast enhanced ultrasound (CEUS) between 2008 and 2018. All examinations were performed by a single radiologist with more than 15 years of experience using a second-generation blood pool contrast agent. The standard of reference was histopathology (n = 60), MRI or CT (n = 75) or long-term CEUS follow up (n = 4). For post processing regions of interests were drawn both inside of target lesions and the liver background. Time–intensity curves were fitted to the CEUS DICOM dataset and the rise time (RT) of contrast enhancement until peak enhancement, and a late-phase ratio (LPR) of signal intensities within the lesion and the background tissue, were calculated and compared between malignant and benign liver lesion using Student’s t-test. Quantitative parameters were evaluated with respect to their diagnostic accuracy using receiver operator characteristic curves. Both features were then combined in a logistic regression model and the cumulated accuracy was assessed. Results: RT of benign lesions (14.8 ± 13.8 s, p = 0.005), and in a subgroup analysis, particular hemangiomas (23.4 ± 16.2 s, p < 0.001) differed significantly to malignant lesions (9.3 ± 3.8 s). The LPR was significantly different between benign (1.59 ± 1.59, p < 0.001) and malignant lesions (0.38 ± 0.23). Logistic regression analysis with RT and LPR combined showed a high diagnostic accuracy of quantitative CEUS parameters with areas under the curve of 0.923 (benign vs. malignant) and 0.929 (hemangioma vs. malignant. Conclusions: Quantified CEUS parameters are helpful to differentiate malignant from benign liver lesions, in particular in case of atypical hemangiomas.


2017 ◽  
Vol 95 ◽  
pp. 378-398 ◽  
Author(s):  
Luigi Grazioli ◽  
Roberta Ambrosini ◽  
Barbara Frittoli ◽  
Marco Grazioli ◽  
Mario Morone

1997 ◽  
Vol 22 (4) ◽  
pp. 410-417 ◽  
Author(s):  
D. Mathieu ◽  
M. Paret ◽  
A.-E. Mahfouz ◽  
F. Caseiro-Alves ◽  
J. Tran Van Nhieu ◽  
...  

2014 ◽  
Vol 11 (12) ◽  
pp. 737-749 ◽  
Author(s):  
Jacques Belghiti ◽  
François Cauchy ◽  
Valérie Paradis ◽  
Valérie Vilgrain

2006 ◽  
Vol 13 (5) ◽  
pp. 398-402 ◽  
Author(s):  
Masato Yamazaki ◽  
Hideki Yasuda ◽  
Souichirou Tsukamoto ◽  
Yoshio Koide ◽  
Tsutomu Yarita ◽  
...  

2005 ◽  
Vol 71 (9) ◽  
pp. 750-753
Author(s):  
Gabriel Akopian ◽  
James Blitz ◽  
Thomas Vander Laan

The treatment of choledocholithiasis discovered incidentally during laparoscopic cholecystectomy is not yet standardized. Options include laparoscopic common bile duct exploration (LCBDE), postoperative endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy (ERCP-ES), and no intervention. We undertook a review of our case series to determine whether LCBDE is obligatory and which LCBDE method is unsuccessful. During the 6-year study period, 91 patients with choledocholithiasis were identified. Fifty-six patients (62%) underwent LCBDE. Thirteen (23%) of these 56 patients subsequently required ERCP. Balloon sweeping of the common bile duct failed in 10 of 21 patients (48% failure) compared to any other combination of techniques with a failure rate of 1/33 (3%; P < 0.001). Two patients did not undergo complete duct exploration because of technical problems. Thirty-five patients (38%) did not undergo LCBDE. Nine of these patients (26%) did not have ERCP-ES. None of the patients who underwent postoperative ERCP-ES required additional procedures or surgery. LCBDE can successfully treat common bile duct stones, with minimal to no morbidity, but is not mandatory for safely treating choledocholithiasis. Additionally, advanced techniques for clearing the common bile duct are more successful. Surgeons should be proficient at performing these techniques.


1999 ◽  
Vol 13 (6) ◽  
pp. 632-633 ◽  
Author(s):  
E. Neri ◽  
D. Caramella ◽  
P. Boraschi ◽  
G. Braccini ◽  
E. D. Lehmann ◽  
...  

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