The term “psychogenic” pain was use liberally during the 20th century. It has been applied in a number of different ways. First, to describe pain originating from psychological/psychiatric (ie, mental) processes. Second, as a way of declaring that, although there may be physical abnormalities, the degree of pain experienced is dictated by psychological states. Finally, to imply that psychological factors co-mingle with physical factors in the experience of pain, especially chronic pain. By its very nature, “psychogenic” implies of separation of mind and body. Most often it has been used as a diagnosis of exclusion—we cannot find the real (ie, medical/physical) cause, so it must be psychological, all but impugning the validity of the patient’s report. In the midst of modern technology and research, and the prevailing philosophical approach to pain (chronic), the term “psychogenic” has exhausted its research, clinical, and practical utility. This chapter provides supporting evidence for this conclusion and research data highlighting the complex and dynamic nature of pain (chronic).