Investigation in gastrointestinal disease

Author(s):  
Satish Keshav ◽  
Alexandra Kent

This chapter discusses investigation in gastrointestinal (GI) disease, including blood tests (full blood count, haematinics, biochemistry, immunology, microbiology, stool investigations), radiology (abdominal plain X-rays, barium studies, ultrasound, CT, MRI), nuclear medicine (SeHCAT scan, HIDA scan, gastric emptying study), endoscopy (oesophagogastroduodenoscopy, lower GI endoscopy, endoscopic retrograde cholangiopancreatography, therapeutic endoscopy, capsule endoscopy), and breath tests (lactulose/glucose-hydrogen breath test, lactose/hydrogen breath test, urea breath test).

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
J. López ◽  
C. Sánchez ◽  
S. N. Fernández ◽  
R. González ◽  
M. J. Solana ◽  
...  

Introduction. Gastrocecal transit time (GCTT) can be measured by exhaled hydrogen after lactulose intake (lactulose-eH2 test). The objectives were to assess whether it is possible to carry out this test in critically ill children with and without mechanical ventilation (MV) and to analyze whether the results are consistent with clinical findings. Methods. Patients admitted to the Pediatric Intensive Care Unit (PICU) for more than 3 days were included. Those with gastrointestinal disease prior to admission were excluded. A modified technique to obtain eH2 from the ventilator tubes was performed. Results. Sixteen patients (37.5% boys) with a median age of 19 (5–86.5) months were included. Five patients (31.2%) were breathing spontaneously but lactulose-eH2 test could not be performed while it could be performed successfully in the 11 patients with MV. Seven patients (63.3%) did not show an eH2 peak. The other 4 showed a median time of 130 min (78.7–278.7 min) from lactulose intake to a 10 ppm eH2 peak. Children with an eH2 peak had intestinal movements earlier [6.5 (1.5–38.5) versus 44 (24–72) hours p=0.545]. Conclusion. Although the designed adaption is useful for collecting breath samples, lactulose-eH2 test may not be useful for measuring GCTT in critically ill children.


2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Nebras Ebrahim Hasan ◽  
Manal Hasan Zainaldeen ◽  
Fatima Abdulameer Almadhoob ◽  
Manaf Ali Yusuf ◽  
Salim Fredericks

Lactose intolerance is associated with the inability to digest significant amounts of lactose. Several conditions have symptoms that overlap with those of lactose intolerance. Thus, it is commonly misdiagnosed. There are established investigation procedures that aid diagnosis which include the lactose challenge and the hydrogen breath tests. However, differential diagnosis remains challenging. We aimed at identifying gaps in knowledge regarding lactose intolerance among medical practitioners using a survey consisting of 15 questions. It was completed by 98 doctors. Most questions were answered correctly by more than half of the participants. There was no significant difference in the frequency of correct answers between the different medical specialists or age of participating doctors. Crucially, one question relating to the hydrogen breath test was answered incorrectly by 85% of the participants. This highlights acceptable knowledge of general issues, but not the diagnostic aspects, of lactose intolerance among doctors.


Author(s):  
C. W. Mehard ◽  
W. L. Epstein

The underlying cause of a disease may not he readily apparent but may have a long history in development. We report one such case which was diagnosed with the aid of the analytical electron microscope.The patient, a 48 yr. old white female, developed a tender nodule on the sole of her foot in December, 1981. Subsequently additional lesions developed on the same foot resulting in deep pain and tenderness. Superficial lesions also extended up to the knee on both legs. No abnormalities were revealed in blood tests or chest X-rays.


2004 ◽  
Vol 118 (10) ◽  
pp. 796-798 ◽  
Author(s):  
M. Daniel ◽  
A.R. Banerjee

Objectives: Pre-admission clinics are traditionally run jointly by nurses and doctors. Within an adult ENT pre-admission clinic, we wished to assess what doctors added tonurses’ pre-clerking, to determine whether doctors were actually needed in the clinic.Methods: Prospective study,looking at how often doctors, seeing patients after ward-based nurses, changed or added to clerking or tests as organized by nurses.Results: Out of 184 patients, doctors changed or added to nurses’ clerking or planned investigations in 47 patients (26 per cent), making 64 different changes. The commonest reasonsfor changes were ordering blood tests (22 changes), chest X-rays (eight), cancelling due to hypertension (seven), altering drug history (five) and requesting electrocardiograms (five changes).Conclusion: Most changes made by doctors could be eliminated by designing a pre-admission clinic protocol that could easily be used by nurses. We recommend that all ENT departments consider implementing nurse-led pre-admission clinics.


2008 ◽  
Vol 54 (8) ◽  
pp. 1730-1735 ◽  
Author(s):  
Arne R. J. Schneider ◽  
Stefanie Klueber ◽  
Hans-Georg Posselt ◽  
Benjamin Funk ◽  
Lydia Murzynski ◽  
...  

2004 ◽  
Vol 144 (6) ◽  
pp. 313-318 ◽  
Author(s):  
Michele Di Stefano ◽  
Antonio Missanelli ◽  
Emanuela Miceli ◽  
Alessandra Strocchi ◽  
Gino Roberto Corazza

2012 ◽  
Vol 57 (5) ◽  
pp. 1330-1335 ◽  
Author(s):  
Ana María Madrid ◽  
Glauben Landskron ◽  
Gabriela Klapp ◽  
Alvaro Reyes ◽  
Carolina Pizarro ◽  
...  

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