Urticaria

2018 ◽  
Author(s):  
Sarah Wakelin
Keyword(s):  
Chronic Urticaria ◽  
Chemical Substance ◽  
Abrupt Onset ◽  
Similar Process ◽  
Contact Urticaria ◽  
Acute Urticaria ◽  
Dermal Tissue ◽  
Physical Urticaria ◽  
Mucous Membranes

Urticaria is an inflammatory complaint characterized by short-lived skin swellings termed ‘wheals’ or ‘hives’. It can be divided into acute urticaria, where the disease has an abrupt onset, and chronic urticaria, where wheals have occurred on a regular basis for over 6 weeks. Physical urticaria is a subgroup of chronic urticaria where an underlying external/physical trigger can be identified, while contact urticaria arises from contact with a chemical substance on the skin or mucous membranes. Angiooedema represents a similar process affecting the deeper dermal tissue and has a predilection for the skin around the eyes and mouth. It may occur in association with urticaria or as an isolated complaint.

Diagnostic features of chronic urticaria

2016 ◽  
Vol 19 (5) ◽  
pp. 290-295
Author(s):  
N. G Kochergin ◽  
P. V Kolkhir ◽  
Olga A. Kosoukhova
Keyword(s):  
Chronic Urticaria ◽  
Eosinophil Cationic Protein ◽  
Autologous Serum ◽  
Diagnostic Features ◽  
Cationic Protein ◽  
Complement Components ◽  
Autologous Serum Skin Test ◽  
Acute Urticaria ◽  
Physical Urticaria ◽  
Working Age

Urticaria is etiologically heterogeneous disease, where the main clinical sign is a wheal. For the duration of the disease course secrete acute and chronic urticaria. If urticaria elements in the skin of the patient are observedfrom several hours to 6 weeks, it is classified as acute urticaria, cutaneous if the process continues for more than 6 weeks, it is a chronic urticaria. The aim of our work was the optimization of diagnosis of chronic urticaria on the basis of the study of clinical and allergological and immunological characteristics of the testing results. The study involved 60 patients between the ages of 18 to 73 years with confirmed clinical diagnosis of chronic urticaria. The study was conducted in the clinic of skin and venereal diseases ofI.M. Sechenov First Medical State Medical University. Conducted clinical and anamnestic examination: medical history, assessment of complaints, determining the severity of urticaria (UAS7), quality of life (CU-Q2oL, DLQI), control of the symptoms of urticaria (UCT); laboratory tests: clinical blood test, C-reactive protein, thyroid hormones and antibodies to thyroid structures, tests to exclude physical urticaria, autologous serum skin test, D-dimer, rheumatoid factor, eosinophil-cationic protein, the total of IgE, antinuclear antibodies , C3 / C4 complement components, protein fractions, coagulation, urinalysis, general analysis offeces, feces on eggs of worms and protozoa. The study was conducted within 1 month and included diagnostic consultation period and 5 consultations every 7 days. Identified specific clinical and laboratory features that can be assigned to the diagnostic criteria for autoimmune form of chronic urticaria, which will continue to pick up these patients rational treatment. The high prevalence of urticaria, a variety offorms of the disease, the presence ofpathology predominantly in patients of working age, often ineffective diagnostic actions cause the urgency of the problem and the need for further study of this disease.

scholarly journals Careful Attention To The History Of Chronic Urticaria Is One Of The Important Factors Of Productive Therapy

2021 ◽  
Vol 03 (02) ◽  
pp. 55-58
Author(s):  
Akhmedov Shavkat Kurbonalievich ◽  
◽  
Ashirov Zohijon Fayozjonovich ◽  
Oripov Rustam Anvarovich ◽  
Siddikov Olim Abdullaevich ◽  
...  
Keyword(s):  
Chronic Urticaria ◽  
External Factors ◽  
Internal Organs ◽  
Acute Urticaria ◽  
Mucous Membranes ◽  
History Of ◽  
Undigested Food ◽  
Exogenous Factors ◽  
Insect Bites ◽  
System 1

Urticaria is an allergic disease characterized by the appearance of blisters on the skin and mucous membranes. The disease can be caused by external factors (temperature, mechanical, chemical) or internal (diseases of internal organs, disorders of the nervous system). [1, 2]. Allergies can be caused by toxins, bacteria, and undigested food. In the diagnosis of the disease, anamnestic data, dermography and various skin allergological tests are used. There are acute (up to 6 weeks) and chronic (more than 6 weeks) urticaria. The latter is characterized by daily or frequent symptoms (blistering, itching, angioedema for 6 weeks or more [3, 4]. During life, 0.5-1% of the entire population of people suffers from chronic urticaria. At the same time, if acute urticaria is usually associated with the action of exogenous factors and allergens (food, medicines, insect bites, etc).

scholarly journals Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria

1996 ◽  
Vol 5 (2) ◽  
pp. 113-115 ◽  
Author(s):  
G. Di Lorenzo ◽  
P. Mansueto ◽  
M. Melluso ◽  
G. Candore ◽  
D. Cigna ◽  
...  
Keyword(s):  
Chronic Urticaria ◽  
Eosinophil Cationic Protein ◽  
Chronic Idiopathic Urticaria ◽  
Blood Eosinophil ◽  
Cationic Protein ◽  
Acute Urticaria ◽  
Asymptomatic Patients ◽  
The Moment ◽  
Blood Eosinophils ◽  
Eosinophil Counts

We have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. The ECP levels and eosinophil counts were measured in the peripheral blood of 15 patients with acute urticaria, 25 with chronic idiopathic urticaria and 10 normal healthy subjects. Blood eosinophil counts and serum ECP levels increased in all patients with acute urticaria. Concerning patients affected by chronic urticaria, taking into account the recrudescence of the disease at the moment of taking the blood sample, only symptomatic patients showed increased eosinophil blood values whereas serum ECP levels were increased both in symptomatic and asymptomatic patients. Furthermore, serum ECP levels in chronic urticaria did not correlate with the peripheral eosinophil counts, as they did in acute urticaria. The results of the present study indicate that eosinophils may play a role in the inflammatory mechanisms in patients with acute and chronic urticaria showing a positive correlation between serum ECP levels and disease activity.

Cobalt-Induced Contact Urticaria Presenting as Chronic Urticaria Due to Intramuscular Vitamin B12 Injections

Dermatitis ◽  
2016 ◽  
Vol 27 (5) ◽  
pp. 313-314
Author(s):  
Jordan Huber ◽  
Jason Ezra Hawkes ◽  
Douglas L. Powell
Keyword(s):  
Vitamin B12 ◽  
Chronic Urticaria ◽  
Contact Urticaria

scholarly journals Autologous Serum Skin Test for Initial Identification of Auto- Antibodies in Chronic Urticaria

2018 ◽  
Vol 19 (2) ◽  
pp. 100-103
Author(s):  
Mohammad Nura Alam ◽  
Mohammad Ali ◽  
Mohammad Moniruzzaman Khan ◽  
Keya Tarafder ◽  
Goutam Kumar Acherjya ◽  
...  
Keyword(s):  
Skin Test ◽  
Chronic Urticaria ◽  
Cost Effective ◽  
Autologous Serum ◽  
P Value ◽  
Effective Measure ◽  
Autologous Serum Skin Test ◽  
Physical Urticaria ◽  
Retrospective Data Analysis ◽  
Initial Identification

Background: Autologous serum skin test (ASST) is easy to perform, cost effective measure for initial identification of auto-antibody in patients suffering from chronic urticaria which may occur due to autoimmune trigger by spontaneously developed auto-antibodies against FcμRI receptor of skin mast cells.Objective: This review is designed to see the positivity of ASST in patients suffering from chronic urticaria.Materials & Methods: This a retrospective data analysis conducted from the records of patients suffered from at least two episodes of urticaria or more in a week for 6 weeks and who did ASST aged more than 10 years between July 2015 to June 2017. These subjects were not pregnant or lactating mother, did not had urticarial vasculitis, predominant co-existing physical urticaria and had negative Hepatitis B antigen and anti-nuclear antibody reports.Results: Total 53 were included in this study of them 33 were female. Mean age was 32 years with a standard deviation (SD) of 11 years. Among study patients 16 (30.2% of total) had a positive ASST result. No age or sex difference was observed in positive ASST cases. In positive cases significant (p-value:<0.001) mean induration difference of 2.75mm with a SD of 1.00 mm observed than induration produced by negative control.Conclusion: ASST is easy and effective tool for initial identification of auto-reactive urticaria.J MEDICINE JUL 2018; 19 (2) : 100-103

scholarly journals Advances in Understanding and Managing Chronic Urticaria

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 177 ◽  
Author(s):  
Yasmin Moolani ◽  
Charles Lynde ◽  
Gordon Sussman
Keyword(s):  
Chronic Urticaria ◽  
Immunoglobulin E ◽  
Treatment Options ◽  
Treatment Algorithm ◽  
Fold Increase ◽  
Line Treatment ◽  
Physical Urticaria ◽  
Chronic Inducible Urticaria ◽  
Autoimmune Urticaria ◽  
Inducible Urticaria

There have been recent advances in the classification and management of chronic urticaria. The new term chronic spontaneous urticaria (CSU) has replaced chronic idiopathic urticaria and chronic autoimmune urticaria. In addition, chronic inducible urticaria (CINDU) has replaced physical urticaria and includes other forms of inducible urticaria, such as cholinergic and aquagenic urticaria. Furthermore, novel research has resulted in a new understanding with guidelines being revised in the past year by both the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA2LEN)/European Dermatology Forum (EDF)/World Allergy Organization (WAO). There are some differences in the recommendations, which will be discussed, but the core updates are common to both groups. The basic treatment for chronic urticaria involves second-generation non-sedating non-impairing H1 antihistamines as first-line treatment. This is followed by up to a 4-fold increase in the licensed dose of these H1 antihistamines. The major therapeutic advance in recent years has been in third-line treatment with omalizumab, a humanized monoclonal anti-immunoglobulin E (anti-IgE) antibody that prevents binding of IgE to the high-affinity IgE receptor. Several multicenter randomized controlled trials have shown safety and efficacy of omalizumab for CSU. There are also some small studies showing efficacy of omalizumab in CINDU. While there were previously many treatment options which were lacking in strong evidence, we are moving into an era where the treatment algorithm for chronic urticaria is simplified and contains more evidence-based, effective, and less toxic treatment options.

Clinical and Epidemiological Differences in Patients with Acute Urticaria and Chronic Urticaria

2016 ◽  
Vol 137 (2) ◽  
pp. AB58 ◽  
Author(s):  
Mehtap Haktanir Abul ◽  
Fazil Orhan ◽  
Zekiye Ilke Kilic Topcu ◽  
Taner Karakas ◽  
Ali Baki
Keyword(s):  
Chronic Urticaria ◽  
Acute Urticaria

The general characteristics of acute urticaria attacks and the factors predictive of progression to chronic urticaria

2013 ◽  
Vol 41 (4) ◽  
pp. 239-245 ◽  
Author(s):  
S. Comert ◽  
E. Celebioglu ◽  
G. Karakaya ◽  
A.F. Kalyoncu
Keyword(s):  
Chronic Urticaria ◽  
Acute Urticaria

scholarly journals REMISSION OF A CASE OF MULTIPLE HYMENOPTERA STINGS-ASSOCIATED CHRONIC URTICARIA DURING VENOM IMMUNOTHERPY

2021 ◽  
Author(s):  
Marco Dubini ◽  
Valerio Pravettoni ◽  
Federica Rivolta ◽  
Giulia Segatto ◽  
Riccardo Asero ◽  
...  
Keyword(s):  
Chronic Urticaria ◽  
Venom Immunotherapy ◽  
Acute Urticaria ◽  
Hymenoptera Sting ◽  
Wasp Stings

The role of Immunotherapy in Chronic Urticaria is unclear, except for isolated circumstances. Hymenoptera sting causes acute urticaria and no report of CU after Hymenoptera sting can be found in the literature. We describe a case of onset of CU after multiple wasp stings that remitted during venom immunotherapy.

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