Anatomy, physiology, and pathology of body fat

2021 ◽  
pp. 1465-1472
Author(s):  
Isabel Teo ◽  
Mark Soldin

Subcutaneous body fat is a distinct anatomical entity with unique physiology, metabolism, and disease. The main roles of fat are energy storage, hormone production, and insulation. Free fatty acids and glycerol can be assembled into triglycerides, and conversely triglycerides can undergo lipolysis. Insulin is the key hormone that controls this fine balance. Pregnancy is associated with increased truncal body fat and breast ptosis. Cellulite is the padded appearance of fat and there is currently no single proven treatment. Lipomas are the most common soft tissue tumour and can be treated with excision or liposuction. Lipodystrophies are disorders characterized by the selective loss of body fat and lipofilling is a useful treatment modality. Panniculitis is the inflammation of subcutaneous fat and treatment involves dealing with the precipitating cause. The plastic surgeon should be familiar with the anatomy, physiology, and pathology of fat in order to treat this wide array of adipose-related conditions.

2017 ◽  
Vol 31 (3) ◽  
pp. 204-215 ◽  
Author(s):  
Kethesparan Paramesparan ◽  
Amit Shah ◽  
Winston J. Rennie

2012 ◽  
Vol 56 (1) ◽  
pp. 96-99
Author(s):  
Yuranga Dilan Weerakkody ◽  
Michael Dray ◽  
Clinton Pinto ◽  
Michael Rosenfeldt ◽  
Michael Flint

2020 ◽  
Vol 44 (3) ◽  
pp. 189-191
Author(s):  
N. Babu Prasath ◽  
J Selvaraj ◽  
M Sasikala ◽  
S. Senthilkumar

2021 ◽  
Vol 14 (1) ◽  
pp. e236661
Author(s):  
Ruchika Kumari ◽  
Cherring Tandup ◽  
Ambuj Agarwal ◽  
Anish Chowdhury

Angiofibroma is a benign soft tissue tumour presenting as a gradually progressive swelling in the vulvovaginal area in women and in the inguinoscrotal region in men. Being a rare tumour, there are only a few case reports in the literature, and among them, presentation as perineal herniation is very rare. En bloc resection of angiofibroma either via laparoscopic or open approach is the choice of treatment to avoid recurrence. Detailed pathological examination and immunohistochemistry workup are imperative to distinguish it from various mesenchymal tumours. Perineal hernia is itself rare and may occur spontaneously or following abdominoperineal resection, sacrectomy or pelvic exenteration. Surgical repair via open transabdominal and transperineal approaches has been described. Here, we report a case of a young woman who presented with spontaneous reducible perineal hernia with a soft tissue tumour as its content, which on histopathological investigation was found to be an angiofibroma.


2012 ◽  
Vol 5 (1) ◽  
pp. 2101791285670486
Author(s):  
Marcel-Philipp Henrichs ◽  
Arne Streitbürger ◽  
Georg Gosheger ◽  
Carsten Surke ◽  
Christian Dierkes ◽  
...  

2021 ◽  
Author(s):  
Nuno Oliveira ◽  
Sofia Carvalho ◽  
Paulo Cunha ◽  
Joni Nunes ◽  
Pedro Varanda ◽  
...  

Abstract PurposeTo describe a very rare case of Synovial Sarcoma affecting cervical spine vertebra.SS is a rare malignant and aggressive soft tissue tumour arising from mesenchymal cells. Primary bone origin SS is a much rarer entity that affects more commonly long bones. Ideal therapeutic strategy is yet to be defined due to very small number of cases reported so far.Case reportA 55-year-old male, construction worker, with no other relevant medical history presented with a progressive tetraparesis after recurring several times during a 4-week period to assistant physician and emergency department complaining about bilateral shoulder pain. Image studies revealed an osteolytic lesion centred on C4 vertebra with intracanalar and intraforaminal extension, causing neurologic compression. Patient was submitted to urgent surgical decompression intervention. C3 and C4 corpectomy and excisional biopsy followed by stabilization with C2-C5 arthrodesis.OutcomesNeurological deficits did not improve after surgery. Histopathological and immunohistochemical analysis revealed phenotypical characteristics of a biphasic Synovial Sarcoma. Patient died 4 weeks after surgery due to a respiratory tract infection.DiscussionSS is a malignant rare and aggressive soft tissue tumour that usually affects young adults. Very few cases of primary bone SS affecting the spine are described in literature. Imaging studies may suggest the diagnosis of synovial sarcoma but definitive diagnosis can only be confirmed by histological and immunohistochemical analysis.The rarity of these lesions demands high clinical suspicion for the diagnosis and due to the low number of cases reported ideal therapeutic strategy is yet to be defined.


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