Biomarkers in acute heart failure

2016 ◽  
Author(s):  
Rajiv Choudhary ◽  
Kevin Shah ◽  
Alan Maisel
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Natriuretic Peptides ◽  
Health Care Systems ◽  
Medical Problem ◽  
National Health Care ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Acute Dyspnoea ◽  
Care Systems ◽  
Neutrophil Gelatinase

Acute heart failure continues to be a worldwide medical problem, associated with frequent readmissions, high mortality, and a profound economic impact on national health care systems. In the past decade, biomarkers have shifted the way in which acute heart failure is managed by the cardiologist. The search for the ideal biomarker to aid in the diagnosis, prognosis, and treatment of acute heart failure is ongoing. The natriuretic peptides have proved extremely useful in determining whether acute dyspnoea has a cardiac aetiology. In addition, recent trials have demonstrated the use of natriuretic peptides in inpatient and outpatient prognosis, as well as in titrating medications in outpatients with chronic heart failure to prevent acute heart failure hospitalizations. Other emerging acute heart failure biomarkers include mid-regional pro-adrenomedullin, mid-regional proatrial natriuretic peptide, troponin, ST2, and neutrophil gelatinase-associated lipocalin.

Biomarkers in acute heart failure

2015 ◽  
Author(s):  
Rajiv Choudhary ◽  
Kevin Shah ◽  
Alan Maisel
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Natriuretic Peptides ◽  
Health Care Systems ◽  
Medical Problem ◽  
National Health Care ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Acute Dyspnoea ◽  
Care Systems ◽  
Neutrophil Gelatinase

Acute heart failure continues to be a worldwide medical problem, associated with frequent readmissions, high mortality, and a profound economic impact on national health care systems. In the past decade, biomarkers have shifted the way in which acute heart failure is managed by the cardiologist. The search for the ideal biomarker to aid in the diagnosis, prognosis, and treatment of acute heart failure is ongoing. The natriuretic peptides have proved extremely useful in determining whether acute dyspnoea has a cardiac aetiology. In addition, recent trials have demonstrated the use of natriuretic peptides in inpatient and outpatient prognosis, as well as in titrating medications in outpatients with chronic heart failure to prevent acute heart failure hospitalizations. Other emerging acute heart failure biomarkers include mid-regional pro-adrenomedullin, mid-regional proatrial natriuretic peptide, troponin, ST2, and neutrophil gelatinase-associated lipocalin.

Biomarkers in acute heart failure

2018 ◽  
Author(s):  
Rajiv Choudhary ◽  
Kevin Shah ◽  
Alan Maisel
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Health Care Systems ◽  
Medical Problem ◽  
National Health Care ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Acute Dyspnoea ◽  
Care Systems ◽  
Neutrophil Gelatinase ◽  
The Ideal

Acute heart failure continues to be a worldwide medical problem, associated with frequent readmissions, high mortality, and a profound economic impact on national health care systems. In the past decade, biomarkers have shifted the way in which acute heart failure is managed by the cardiologist. The search for the ideal biomarker to aid in the diagnosis, prognosis, and treatment of acute heart failure is ongoing. The natriureticfc peptides have proved extremely useful in determining whether acute dyspnoea has a cardiac aetiology. In addition, recent trials have demonstrated the use of natriuretic peptides in inpatient and outpatient prognosis, as well as in titrating medications in outpatients with chronic heart failure to prevent acute heart failure hospitalizations. Other emerging acute heart failure biomarkers include mid-regional pro-adrenomedullin, mid-regional proatrial natriuretic peptide, troponin, ST2, and neutrophil gelatinase-associated lipocalin.

Biomarkers in acute heart failure

2017 ◽  
Author(s):  
Rajiv Choudhary ◽  
Kevin Shah ◽  
Alan Maisel
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Health Care Systems ◽  
Medical Problem ◽  
National Health Care ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Acute Dyspnoea ◽  
Care Systems ◽  
Neutrophil Gelatinase ◽  
The Ideal

Acute heart failure continues to be a worldwide medical problem, associated with frequent readmissions, high mortality, and a profound economic impact on national health care systems. In the past decade, biomarkers have shifted the way in which acute heart failure is managed by the cardiologist. The search for the ideal biomarker to aid in the diagnosis, prognosis, and treatment of acute heart failure is ongoing. The natriureticfc peptides have proved extremely useful in determining whether acute dyspnoea has a cardiac aetiology. In addition, recent trials have demonstrated the use of natriuretic peptides in inpatient and outpatient prognosis, as well as in titrating medications in outpatients with chronic heart failure to prevent acute heart failure hospitalizations. Other emerging acute heart failure biomarkers include mid-regional pro-adrenomedullin, mid-regional proatrial natriuretic peptide, troponin, ST2, and neutrophil gelatinase-associated lipocalin.

Biomarkers in acute heart failure

2021 ◽  
pp. 409-424
Author(s):  
Rajiv Choudhary ◽  
Nicholas Wettersten ◽  
Kevin Shah ◽  
Alan Maisel
Keyword(s):  
Heart Failure ◽  
Health Care ◽  
Acute Heart Failure ◽  
Health Care Systems ◽  
High Sensitivity ◽  
Medical Problem ◽  
National Health Care ◽  
Acute Dyspnoea ◽  
Galectin 3 ◽  
Care Systems

Acute heart failure continues to be a worldwide medical problem, associated with frequent readmissions, high mortality, and a profound economic impact on national health care systems. Biomarkers have shifted the way in which acute heart failure is managed by the cardiologist. The search for the ideal biomarker to aid in the diagnosis, prognosis, and treatment of acute heart failure is ongoing. The natriuretic peptides have come close to an ideal biomarker and prove extremely useful in determining whether acute dyspnoea has a cardiac aetiology. Furthermore, they are useful for prognosis and may have a role in guiding management of heart failure. Additionally, high-sensitivity troponin, sST2, and galectin-3 are increasingly used with mounting clinical evidence for utility. Other emerging acute heart failure biomarkers include mid-regional pro-adrenomedullin, bio-adrenomedulin, mid-regional proatrial natriuretic peptide, and procalcitonin.

scholarly journals Prognostic value of neutrophil gelatinase-associated lipocalin in acute heart failure

2013 ◽  
Vol 165 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Margarida Alvelos ◽  
Patrícia Lourenço ◽  
Carla Dias ◽  
Marta Amorim ◽  
Joana Rema ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Prognostic Value ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Neutrophil Gelatinase

scholarly journals Biomarkers in Acute Decompensated Heart Failure

2015 ◽  
Vol 7 ◽  
pp. CMT.S18476
Author(s):  
Andrew N. Rosenbaum ◽  
Wayne L. Miller
Keyword(s):  
Heart Failure ◽  
Natriuretic Peptides ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Cardiac Troponin T ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Galectin 3 ◽  
Neutrophil Gelatinase

Acute decompensated heart failure (ADHF) is a prominent condition whose frequency is increasing, especially in the context of an aging population. The ability to discern the cause of undifferentiated dyspnea in acute presentations is an increasing struggle. In this review, we seek to explore the various biomarkers that have been studied for the diagnosis of ADHF and their respective clinical utilities as the most recent data would suggest. Natriuretic peptides, galectin-3, soluble ST2, adrenomedullin, cardiac troponin-T, neutrophil gelatinase-associated lipocalin, and copeptin are reviewed. Of these biomarkers, natriuretic peptides are the most thoroughly evaluated and show the most promise for diagnosis or exclusion of acute heart failure, though other biomarkers can add significant utility in the form of prognostication.

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