Case 4.26

Author(s):  
Christine U. Lee ◽  
James F. Glockner

78-year-old man with a history of renal cell carcinoma Axial fat-suppressed FRFSE T2-weighted images (Figure 4.26.1) reveal multiple mildly hyperintense lesions in the pancreatic body and head. Arterial phase (Figure 4.26.2) and venous phase (Figure 4.26.3) postgadolinium 3D SPGR images also demonstrate multiple hypervascular pancreatic lesions. Notice also the absent left kidney (from a nephrectomy) and multiple solid enhancing lesions in the right kidney....

2010 ◽  
Vol 10 ◽  
pp. 590-602 ◽  
Author(s):  
Alessandro Sindoni ◽  
Massimo Rizzo ◽  
Giovanni Tuccari ◽  
Antonio Ieni ◽  
Valeria Barresi ◽  
...  

The thyroid gland is a rare site of clinically detectable tumor metastasis and kidneys are frequently the site of the parent malignancy. In the present review on thyroid metastases from renal cell carcinoma, cases were searched on PubMed by entering the strings: “renal carcinoma [or“hypernephroma”] AND thyroid metastasis/metastases”. Thus, we retrieved a total of 111 cases that were published between 1964 and 2007, a total that became 113 by adding two patients observed by us. The female to male ratio was 1.35:1. The primary renal cancer was almost always unilateral (90%) (with no significant side preference) and only rarely bilateral (9% in men, 4% in women), whereas bilaterality of thyroid metastases was relatively more frequent (28%). Thyroid metastasis from renal cancer was commonly single with a unique node that appears solid and hypoechoic at ultrasonography, approximately 9 years after nephrectomy. Concordance of lateralization was insignificantly greater for the right kidney/right thyroid lobe pattern (54%) than for the left kidney/left thyroid lobe pattern (40%), regardless of gender. Finally, survival was longer for women. Thyroid metastases, even if rare in the clinical practice, must be considered in the differential diagnosis of a thyroid nodule, particularly in patients who have a history of malignancies.


2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Abelardo Loya-Solis ◽  
Lucía Alemán-Meza ◽  
Luis Carlos Canales-Martínez ◽  
Rodolfo Franco-Márquez ◽  
Alim Adriana Rincón-Bahena ◽  
...  

Renal cell carcinoma is the most common malignancy of the kidney in adults. In children, however, it only accounts for an estimated 1.8 to 6.3% of all pediatric malignant renal tumors. Papillary renal cell carcinoma is the second most common type of renal cell carcinoma in children. We present the case of a 12-year-old boy with a 2-month history of abdominal pain, unexplained weight loss, and gross hematuria. Computed tomography revealed a horseshoe kidney and a well-defined mass of 4 cm arising from the lower pole of the right kidney. Microscopically the tumor was composed of papillae covered with cells with abundant eosinophilic cytoplasm and high-grade nuclei with prominent nucleoli. Immunohistochemistry was performed; EMA, Vimentin, and AMACR were strongly positive while CK7, CD10, RCC antigen, TFE3, HMB-45, and WT-1 were negative. Currently, 10 months after the surgical procedure, the patient remains clinically and radiologically disease-free.


Author(s):  
Sowjanya Gandla ◽  
Veena Ramaswamy ◽  
Vishal Rao

<p>We describe 3 rare cases of metastatic renal cell carcinoma in the head and neck region. Our first case was a 72 years old male presented with profuse bleeding from the left ear. On examination, proliferative, pink, friable mass was present in the left external auditory canal. On eliciting the detailed history, it was found that patient had renal cell carcinoma in the left kidney four years back and underwent left radical nephrectomy. Patient underwent left lateral temporal bone resection with cul-de-sac closure. Histopathological examination of the specimen showed metastatic renal cell carcinoma. Our second case was a 64 years old male presented with complaints of growth in the oral cavity of 1 month duration. On examination, 5×3 cms proliferative growth was present in the hard palate. Biopsy from the growth in the hard palate showed metastatic renal cell carcinoma. Patient gave history of renal cell carcinoma in the past for which he did not receive treatment. Our third case was a 45 years old male who presented to us with a diffuse swelling in the left temporal region of 2 months duration. On examination, 3×2 cms swelling was present in the left temporal region. Patient had history of renal cell carcinoma of left kidney and underwent left nephrectomy one year prior to the presentation of the left temporal swelling. Ultrasonography guided biopsy of the left temporal region showed metastatic renal cell carcinoma.</p>


2014 ◽  
Vol 11 (1) ◽  
pp. 94-95 ◽  
Author(s):  
S SM Aslam ◽  
H Sridhar ◽  
MY Rao

The synchronous occurrence of primary renal cell carcinoma with gastric cancer is very rare. We report a case of 41 year old male who presented on 05/07/2011 to M S Ramaiah hospital, Bangalore with history of fever, pain abdomen and malena. Ultrasound abdomen and pelvis showed large heterogenous mass arising from the upper pole of left kidney. Computed tomography of the abdomen showed left renal cell carcinoma. Renal biopsy showed features consistent with renal cell carcinoma – clear cell type. Oesophagogastroduodenoscopy revealed gastric polypoidal growth. Gastric biopsy from the growth revealed poorly differentiated adenocarcinoma of stomach. We report this case to highlight a rare occurrence of synchronous malignancy of stomach and kidney. DOI: http://dx.doi.org/10.3126/kumj.v11i1.11053 Kathmandu University Medical Journal Vol.11(1) 2013: 94-95


2014 ◽  
Vol 8 (3-4) ◽  
pp. 188 ◽  
Author(s):  
Lenka Bauerová ◽  
Pavel Dundr ◽  
Daniela Fischerová ◽  
Michal Pešl ◽  
Michal Zikán ◽  
...  

We report on a 61-year-old woman with a history of right-sided nephrectomy for clear cell renal cell carcinoma (RCC) occurring 21 years ago; she currently presented with a bilateral ovarian tumour. Histologically, the tumour of both ovaries was clear cell carcinoma. Immunohistochemically, the tumour cells were positive for vimentin, RCC marker, epithelial membrane antigen, cytokeratin AE1/3 and CD10. Cytokeratin 7, CA125, HMWCK, estrogen and progesterone receptors were all negative. Based on the morphologyand immunophenotype of the tumour, we established a diagnosis of late metastasis of RCC in the ovaries. A postoperative abdominal computed tomography scan, however, revealed a tumour mass solely in the left kidney, which had not been visible in the preoperative ultrasound. The patient underwent nephron-sparing surgery and a biopsy showed the tumour to be clear cell RCC. Metastasis of RCC to the ovaries is rare, and to the best of our knowledge, only 24 cases have been reported to date. However, due to the different treatments and prognosis, the distinction between a primary ovarian tumour and metastasis of RCC is important.


2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
X. Vandemergel

A case of solitary intrathyroid metastasis is described in a 60-year-old male patient. He had a history of renal cell carcinoma classified as T1b resected 23 years earlier. A mass was palpable in the right thyroid lobe. Ultrasound showed a hypoechoic polylobular nodule with intense vascularisation in the right lobe. Fine needle aspiration cytology was normal, but thyroidectomy was performed due to mass enlargement, the ultrasound pattern, and the oncological history. Histological examination revealed the presence of an intrathyroid metastasis of renal cell carcinoma. The bone scan and thoracoabdominal CT scan were normal. Postoperative care was uneventful.


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Massimo Ralli ◽  
Giancarlo Altissimi ◽  
Rosaria Turchetta ◽  
Mario Rigante

Metastases in the paranasal sinuses are rare; renal cell carcinoma is the most common cancer that metastasizes to this region. We present the case of a patient with a 4-month history of a rapidly growing mass of the nasal pyramid following a nasal trauma, associated with spontaneous epistaxis and multiple episodes of hematuria. Cranial CT scan and MRI showed an ethmoid mass extending to the choanal region, the right orbit, and the right frontal sinus with an initial intracranial extension. Patient underwent surgery with a trans-sinusal frontal approach using a bicoronal incision combined with an anterior midfacial degloving; histological exam was compatible with a metastasis of clear cell renal cell carcinoma. Following histological findings, a total body CT scan showed a solitary 6 cm mass in the upper posterior pole of the left kidney identified as the primary tumor. Although rare, metastatic renal cell carcinoma should always be suspected in patients with nasal or paranasal masses, especially if associated with symptoms suggestive of a systemic involvement such as hematuria. A correct early-stage diagnosis of metastatic RCC can considerably improve survival rate in these patients; preoperative differential diagnosis with contrast-enhanced imaging is fundamental for the correct treatment and follow-up strategy.


2014 ◽  
Vol 13 (3) ◽  
pp. 80-83
Author(s):  
Mohammad Ismail Hossain ◽  
Imtiaz Ahmed ◽  
Pradip Bhattacharjee ◽  
M Sahab Uddin Ahamad ◽  
Zillur Rahman

A 50 years old non-smoker female with the history of right flank pain and hematuria surgically treated with right sided radical nephrectomy. Macroscopically it showed a large growth located at the lower pole of the right kidney. Histologically the tumor was composed of exuberant sarcomatous elements predominantly malignant fibrous histiocytoma like pattern and  diagnosed as sarcomatoid renal cell carcinoma. There was no scope for immunohistological analysis of that tumor in our setup. It is important to recognize the sarcomatoid component in the renal tumors because of its aggressive behavior and adverse prognosis. We report herein a case of sarcomatoid renal cell carcinoma histomorphogically.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i3.21039


2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Irzi Mohamed ◽  
Mhanna Tarik ◽  
Aynaou Mohammed ◽  
Wassim Alaoui ◽  
Ouraghi Abdelghani ◽  
...  

Abstract Renal hydatid cyst is a rare disease comprising of about 2–3% of all locations. We present a case of renal hydatid disease in a 48-year-old female patient who presented with a history of left flank pain without fever or hematuria. Ultrasonography and computed tomography showed a 3-cm cystic lesion Bosniak IV occupying the mid-zone of the left kidney diagnosed as renal malignancy. Laparoscopic partial nephrectomy was performed, but the histopathological examination of the lesion revealed hydatid cysts. Isolated renal hydatid cyst is very rare, especially in developed countries and can be misdiagnosed as a renal cell carcinoma pre-operatively.


Author(s):  
Giri Pranav ◽  
Vasugi Arumugam ◽  
Susruthan Murali ◽  
Praveen Paul ◽  
K Natarajan

Oncocytoma is a rare epithelial tumour composed of oncocytes which are epithelial cells with excessive amount of mitochondria. The tumour is most often benign, and diagnosis can be made on the basis of histopathological examination. Here, the authors present a 64-year-old female patient, with complaints of abdominal discomfort and flank pain, along with history of loss of weight and appetite for one month. Radiology showed a left renal mass of measuring 9×7×4.5 cm involving the upper and middle pole suggestive of malignancy. Following which radical nephrectomy was done. Examination of gross specimen showed a fairly circumscribed brownish lesion in the upper and middle pole of left kidney measuring 8.8×7×4.5 cm with a central scar. There was no evidence of hilar and perirenal fat invasion. Histology showed sheets of large polygonal eosinophilic cells with centrally placed nucleus. The differentials were eosinophilic variant of clear cell renal cell carcinoma, chromophobe renal cell carcinoma and oncocytoma. A panel of Immunohistochemical (IHC) markers was performed for further categorisation and the lesional cells were positive for CD 117 and negative for CD 7 and CD 10. This ruled out the differentials and confirmed oncocytoma, thus ruling out the necessity for chemotherapy.


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