scholarly journals Expeditionary Immersion Circulating Heating Device: A Promising Technique for Treating Frostbite Injuries and Warming Intravenous Fluids in a Forward Deployed Cold Weather Environment

2020 ◽  
Vol 185 (11-12) ◽  
pp. e2039-e2043
Author(s):  
Eric M Vinceslio ◽  
Zane Fayos ◽  
Aaron Bernadette ◽  
Jan-Michael Van Gent

Abstract Introduction Cold weather injuries require prompt warm water immersion therapy, which proves to be a difficult task in the cold austere environment. Current guidelines recommend 104 °F water immersion, but producing and maintaining large volumes of warm water is challenging in sub-freezing temperatures. We describe a novel process of utilizing a sous vide immersion circulator to maintain warm fluids for immersion therapy and efficient fluid rewarming in a cold forward-deployed setting for the treatment of cold weather injuries in an effort to bridge the gap between current medical guidelines and practices. Materials and Methods Large water cans were warmed to 104 °F with the immersion circulator. A thermometer was inserted into a 1-inch steak, frozen to 30 °F, and placed in a basin with only the warmed water while the internal temperature was monitored until physiologic temperature was achieved. The time to this endpoint was recorded. A 1-L bag of normal saline and a 450-mL bag of whole blood were also separately warmed by the same technique. The temperature of the normal saline was monitored at 0-, 5-, 7-, 8-, 9-, and 10 -minute intervals. The process was similarly repeated, measuring the whole blood temperature at 0-, 5-, 7-, and 10-minute intervals. Results Ambient internal tent temperatures averaged 54 °F; outdoor temperatures were consistently sub-freezing. The 5-gallon cans of water at ambient temperature heated to 104 °F in 15 minutes. The water temperature remained constant for 3 weeks with the circulator running. The frozen steak started at 30 °F and reached 98 °F in 52 minutes and 45 seconds. The bag of normal saline and whole blood, refrigerated to 39 °F, achieved temperatures of 102 °F and 94 °F respectively after 10 minutes. Conclusion A heating immersion circulator device is a lightweight, flameless, and inexpensive way to consistently heat large volumes of water for treatment of cold weather injuries, hypothermia, and whole blood rewarming in a cold austere environment.

Author(s):  
Manju Gari ◽  
Kumari Ranjeeta ◽  
Lakhan Majhee ◽  
Akhilesh Kumar ◽  
Sumit Kumar Mahato

Background: Pain is the most common reason patients seek medical care. Increased level of monoamines (serotonin and norepinephrine) in synaptic clefts lead to changes in pain threshold and induce antinociception. The study was carried out to evaluate antinociceptive effect of paroxetine in albino rats and to probe into its possible mechanism of action. The study was carried out to evaluate anti-nociceptive effect of paroxetine in albino rats.Methods: Male Albino rats of average weight 150-240gms were used. The drugs used were paroxetine 5mg/Kg, pethidine 5mg/kg (standard drug). Anti-nociceptive effect tested by using thermal method i.e. Tail flick response and Tail warm water immersion method.Results: In this study, Anti-nociceptive effect of respective drugs were measured by using two methods i.e. tail flick test and tail warm water immersion method at 0 min., 30 min., 60 min. and 90min.after administration of drugs. Reaction time started to increase from baseline at 0 min. and peak effect was seen at 60 min. then it started to decrease at 90 min. in almost all the groups except in control group.Conclusions: Paroxetine have significant analgesic effect in acute pain, which may be mediated via central and peripheral mechanisms. Efficacy of Paroxetine is almost equal to that of standard drug pethidine in acute pain management.


JAMA ◽  
1967 ◽  
Vol 200 (8) ◽  
pp. 716b-716
Keyword(s):  

1985 ◽  
Vol 248 (1) ◽  
pp. E51-E57
Author(s):  
B. Cianciaruso ◽  
S. Fukuda ◽  
M. R. Jones ◽  
J. D. Kopple

Previous studies are equivocal as to whether the dog kidney produces histidine. Because one possible source of renal histidine is carnosine (beta-alanyl-L-histidine), we investigated net renal production (release) or utilization (uptake) (Qmet) of histidine and carnosine in 19 female dogs after they were fed histidine-free (9 dogs) or histidine-containing diets (10 dogs). Diets were fed in short-(2-11 days) or long-term (52-57 days) studies. Dogs were infused with half-normal saline for 120 min followed by an infusion of half-normal saline containing carnosine, 50 mumol/min. Renal Qmet histidine, calculated from either plasma or whole blood values, was positive during infusion of half-normal saline. During carnosine infusion, Qmet histidine increased markedly, and there was net renal uptake of carnosine. The Qmet histidine and carnosine were not different in the dogs fed histidine-free vs. histidine-containing diets. Thus there is net renal release of histidine in female dogs that increases when carnosine is administered. Qmet histidine or carnosine do not change adaptively when dogs are fed histidine-free diets.


Water ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1499 ◽  
Author(s):  
Dongmei Yang ◽  
Zhen Ren ◽  
Zhiqun Guo ◽  
Zeyang Gao

When operated under large water immersion, surface piercing propellers are prone to be in heavy load conditions. To improve the hydrodynamic performance of the surface piercing propellers, engineers usually artificially ventilate the blades by equipping a vent pipe in front of the propeller disc. In this paper, the influence of artificial ventilation on the hydrodynamic performance of surface piercing propellers under full immersion conditions was investigated using the Computational Fluid Dynamics (CFD) method. The numerical results suggest that the effect of artificial ventilation on the pressure distribution on the blades decreases along the radial direction. And at low advancing speed, the thrust, torque as well as the efficiency of the propeller are smaller than those without ventilation. However, with the increase of the advancing speed, the efficiency of the propeller rapidly increases and can be greater than the without-ventilation case. The numerical results demonstrates the effectiveness of the artificial ventilation approach for improving the hydrodynamic performance of the surface piercing propellers for high speed planning crafts.


1997 ◽  
Vol 162 (9) ◽  
pp. 610-611 ◽  
Author(s):  
William Humphrey ◽  
Ronald Ellyson
Keyword(s):  

1998 ◽  
Vol 19 (6) ◽  
pp. 341-353 ◽  
Author(s):  
T. J. Walters ◽  
K. L. Ryan ◽  
J. C. Belcher ◽  
J. M. Doyle ◽  
M. R. Tehrany ◽  
...  

2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Bente Grüner Sveälv ◽  
Åsa Cider ◽  
Margareta Scharin Täng ◽  
Eva Angwald ◽  
Dimitris Kardassis ◽  
...  

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