This chapter outlines the first four stages in the process of designing and delivering arts in health interventions. Using business models from industry, management, and health care, it provides a step-by-step guide to conceptualizing and planning effective arts in health interventions that meet a real need within health care. It shows how to scope national and local opportunities, identify specific challenges that the arts could address, select appropriate target groups, understand the needs of patients, public, and staff, undertake consultations, identify relevant research, develop initial ideas, plan for a pilot, and model the impact that the intervention could have. These steps will provide the foundation for a creative and novel intervention with the potential to have real impact and sustainability.