scholarly journals Loss of chromosome 14 increases the radiosensitivity of CGL1 human hybrid cells but lowers their susceptibility to radiation-induced neoplastic transformation

Mutagenesis ◽  
2000 ◽  
Vol 15 (3) ◽  
pp. 187-193 ◽  
Author(s):  
M. S. Mendonca
Keyword(s):  
Neoplastic Transformation ◽  
Hybrid Cells ◽  
Chromosome 14 ◽  
Radiation Induced

Delayed Heritable Damage and Epigenetics in Radiation-Induced Neoplastic Transformation of Human Hybrid Cells

1993 ◽  
Vol 134 (2) ◽  
pp. 209 ◽  
Author(s):  
Marc S. Mendonca ◽  
Ronald J. Antoniono ◽  
J. Leslie Redpath
Keyword(s):  
Neoplastic Transformation ◽  
Hybrid Cells ◽  
Radiation Induced

A Radiation-Induced Acute Apoptosis Involving TP53 and BAX Precedes the Delayed Apoptosis and Neoplastic Transformation of CGL1 Human Hybrid Cells

2005 ◽  
Vol 163 (6) ◽  
pp. 614-622 ◽  
Author(s):  
Marc S. Mendonca ◽  
Brendan M. Mayhugh ◽  
Berry McDowell ◽  
Helen Chin-Sinex ◽  
Martin L. Smith ◽  
...  
Keyword(s):  
Neoplastic Transformation ◽  
Hybrid Cells ◽  
Radiation Induced

Neoplastic Transformation of Human Hybrid Cells by γ Radiation: A Quantitative Assay

1987 ◽  
Vol 110 (3) ◽  
pp. 468 ◽  
Author(s):  
J. L. Redpath ◽  
C. Sun ◽  
M. Colman ◽  
E. J. Stanbridge
Keyword(s):  
Neoplastic Transformation ◽  
Quantitative Assay ◽  
Hybrid Cells ◽  
Γ Radiation

Gene transfer by means of cell fusion I. Statistical mapping of the human X-chromosome by analysis of radiation-induced gene segregation

1977 ◽  
Vol 25 (1) ◽  
pp. 17-37
Author(s):  
S.J. Goss ◽  
H. Harris
Keyword(s):  
Gene Transfer ◽  
Genetic Mapping ◽  
Cell Fusion ◽  
X Chromosome ◽  
Human Cells ◽  
Hybrid Cells ◽  
Gene Segregation ◽  
Radiation Induced ◽  
Chromosome Exchanges ◽  
Lethal Doses

Hybrid cells were obtained by virus-induced fusion of hamster cells with irradiated human cells. The analysis of such hybrids permits a study of the effects of lethal doses of radiation on human cells and provides a method of sub-chromosomal genetic mapping that is independent of karyological analysis. Radiation-induced chromosome exchanges are shown to be extremely localized, and a map of 4 X-linked genes is presented.

Loss of Suppressor Loci on Chromosomes 11 and 14 May Be Required for Radiation-Induced Neoplastic Transformation of HeLa × Skin Fibroblast Human Cell Hybrids

1998 ◽  
Vol 149 (3) ◽  
pp. 246 ◽  
Author(s):  
Marc S. Mendonca ◽  
Kelly Howard ◽  
Clare L. Fasching ◽  
Daphne L. Farrington ◽  
Lael A. Desmond ◽  
...  
Keyword(s):  
Human Cell ◽  
Skin Fibroblast ◽  
Neoplastic Transformation ◽  
Cell Hybrids ◽  
Radiation Induced
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