scholarly journals PCR amplification of tandemly repeated DNA: analysis of intra- and interchromosomal sequence variation and homologous unequal crossing-over in human alpha satellite DNA

1992 ◽  
Vol 20 (22) ◽  
pp. 6033-6042 ◽  
Author(s):  
Peter E. Warburton ◽  
Huntington F. Willard
2020 ◽  
Vol 53 (02) ◽  
pp. 08-11
Author(s):  
Aytakin Hasanova

Heterochromatin of centromeric chromosome regions contains late replicating, largely repetitive DNA. It is suggested that heterochromatin participates in chromosome pairing, crossing-over and in chromosome disjunction control (1,3). Centromeric heterochromatin, a variety of heterochromatin, is a tightly packed form of DNA.Centromeric heterochromatin is a constituent in the formation ofactive centromeres in most higher-order organisms; the domain exists on both mitotic and interphase chromosomes. (4,5,6,8) Centromeric heterochromatin is usually formed on alpha satellite DNA in humans; however, there have been cases where centric heterochromatin and centromeres have formed on originally euchromatin domains lacking alpha satellite DNA; this usually happens as a result of a chromosome breakage event and the formed centromere is called a neocentromere.


Genomics ◽  
1991 ◽  
Vol 11 (2) ◽  
pp. 324-333 ◽  
Author(s):  
Peter E. Warburton ◽  
Gillian M. Greig ◽  
Thomas Haaf ◽  
Huntington F. Willard

1991 ◽  
Vol 33 (1) ◽  
pp. 42-48 ◽  
Author(s):  
B. Marçais ◽  
J. P. Charlieu ◽  
B. Allain ◽  
E. Brun ◽  
M. Bellis ◽  
...  

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