TMS: neurodevelopment and perinatal insults

2012 ◽  
Author(s):  
Marjorie A. Garvey
Keyword(s):  
Motor Function ◽  
Brain Structures ◽  
Neural Substrates ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Future Studies ◽  
Neural Substrate ◽  
The Central Nervous System ◽  
Nervous Development ◽  
Motor Abnormalities

Neural substrate for changes in neuromotor skills of typically developing children involves the complex and organized maturation of underlying brain structures. This article gives an overview of the changes that occur in motor function, as children get older and those aspects of central nervous development which may form the neural substrates of motor function development. It describes those TMS evoked parameters, related to the motor system, that have been studied in both typically developing children and in those who have suffered perinatal insults to the central nervous system. TMS has its limitations and is especially useful when used in combination with other neurophysiological modalities. The focus for future studies should be on correlating TMS evoked parameters with behavioural measures in typically developing children and explanation of the neural substrates of the motor abnormalities in children with perinatal insults and developmental disabilities.

scholarly journals Tools and Techniques Used With Robotic Devices to Quantify Upper-Limb Function in Typically Developing Children: A Systematic Review

2020 ◽  
Vol 9 ◽  
pp. 117957272097901
Author(s):  
Stephan CD Dobri ◽  
Hana M Ready ◽  
Theresa Claire Davies
Keyword(s):  
Systematic Review ◽  
Outcome Measures ◽  
Motor Function ◽  
Upper Limb ◽  
Rate Of Change ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Upper Limb Function ◽  
Robotic Devices ◽  
Tools And Techniques

Background: Robotic devices have been used to quantify function, identify impairment, and rehabilitate motor function extensively in adults, but less-so in younger populations. The ability to perform motor actions improves as children grow. It is important to quantify this rate of change of the neurotypical population before attempting to identify impairment and target rehabilitation techniques. Objectives: For a population of typically developing children, this systematic review identifies and analyzes tools and techniques used with robotic devices to quantify upper-limb motor function. Since most of the papers also used robotic devices to compare function of neurotypical to pathological populations, a secondary objective was introduced to relate clinical outcome measures to identified robotic tools and techniques. Methods: Five databases were searched between February 2019 and August 2020, and 226 articles were found, 19 of which are included in the review. Results: Robotic devices, tasks, outcome measures, and clinical assessments were not consistent among studies from different settings but were consistent within laboratory groups. Fifteen of the 19 articles evaluated both typically developing and pathological populations. Conclusion: To optimize universally comparable outcomes in future work, it is recommended that a standard set of tasks and measures is used to assess upper-limb motor function. Standardized tasks and measures will facilitate effective rehabilitation.

scholarly journals Theory of Mind Abilities and Social Competence in Preschool Children

2019 ◽  
Vol 09 (01) ◽  
pp. 09-11
Author(s):  
Shrunga Manchanapura Shivalingaiah ◽  
Fathimath Ramseena ◽  
Nafeesath Shareen
Keyword(s):  
Theory Of Mind ◽  
Social Life ◽  
True Belief ◽  
False Belief ◽  
Clinical Population ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Future Studies ◽  
Objective Theory ◽  
Mixed Responses

Abstract Background and Objective Theory of mind (ToM) is the ability that can be attributed to mental status beliefs, intents, emotions, proficiency, etc., to oneself and to others, and the understanding that others also have intentions, conceptions, desires, and perspectives that are different from one’s own. Daily social life depends on the ability to evaluate the behavior of other people on the basis of their mental state such as their beliefs, intentions, compassions, and goals. This study was conducted to explore the ToM abilities in preschoolers. Methods A total of 36 preschoolers participated in the study. Two stories were narrated to the children, the classic Sally-Anne Task and the Smarty’s Task. In both the tasks, the responses of the children were scored as either true belief or false belief. Results The results of the present study revealed mixed responses among the preschoolers. It was found that 3- to 4-year-old children had more false beliefs for both the tasks when compared with 4- to 5-year-old. Conclusion This study highlights the importance of ToM abilities in typically growing children and other clinical population. It can be concluded that the ToM abilities were improved in typically developing children. Future studies are required to explore the higher levels of embedding of ToM, and also to incorporate it in the clinical population.

scholarly journals Robot-Assisted Therapy Influence on Kinematic and EMG Activity in the Upper Limb for Children with Cerebral Palsy

2020 ◽  
Author(s):  
Sana Raouafi ◽  
Maxime Raison ◽  
Sofiane Achiche
Keyword(s):  
Cerebral Palsy ◽  
Motor Function ◽  
Upper Limb ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Robot Assisted ◽  
Function Index ◽  
Children With Cerebral Palsy ◽  
Before And After ◽  
Inertial Measurements

Aim: To develop an index for quantitative assessment of the upper limb motor function in children with cerebral palsy before and after robot-assisted therapy. Method: An upper limb motor function index was developed using kinematic, surface electromyography and three-axis inertial measurements unit data collected from 15 children with cerebral palsy (CP) and 15 typically developed children. Children with CP underwent 18 robot-assisted therapy sessions with the REAplan device. All children were evaluated, using kinematic data from the REAplan, electromyography and three-axis inertial measurements unit readings from its accelerometer. A principal component analysis was conducted to produce an evaluation index, which is able to detect the deviation from the upper limb motor function of typically developing children group. Children with CP were evaluated twice before and after the intervention with Box and Blocks test and Finger-To-Nose test. The discriminative and concurrent validity of the upper limb motor function index were investigated. Results: The upper limb motor function index was higher in children with CP post therapy (p<0.001). Finger-To-Nose test values improved after robot-assisted therapy (p<0.03). A weak but positive correlation was observed between upper limb motor function index and clinical tests (r=0.012, p=0.95 and r=0.13, p= 0.54 for Box and Blocks test and Finger-To-Nose test respectively). Interpretation: The upper limb motor function index successfully differentiated between the typically developing children and children with CP and was effective in assessing the improvement of the upper limb motor function after robot-assisted therapy. The upper limb motor function index could be extended to assess and monitor rehabilitation therapies of other populations, such as those with stroke and Parkinson’s disease.

scholarly journals Using Technology to Identify Children With Autism Through Motor Abnormalities

2021 ◽  
Vol 12 ◽  
Author(s):  
Roberta Simeoli ◽  
Nicola Milano ◽  
Angelo Rega ◽  
Davide Marocco
Keyword(s):  
Cognitive Task ◽  
Neurodevelopmental Disorder ◽  
Children With Autism ◽  
Typically Developing ◽  
Autistic Children ◽  
Typically Developing Children ◽  
Motor Patterns ◽  
Starting Point ◽  
Tablet Device ◽  
Motor Abnormalities

Autism is a neurodevelopmental disorder typically assessed and diagnosed through observational analysis of behavior. Assessment exclusively based on behavioral observation sessions requires a lot of time for the diagnosis. In recent years, there is a growing need to make assessment processes more motivating and capable to provide objective measures of the disorder. New evidence showed that motor abnormalities may underpin the disorder and provide a computational marker to enhance assessment and diagnostic processes. Thus, a measure of motor patterns could provide a means to assess young children with autism and a new starting point for rehabilitation treatments. In this study, we propose to use a software tool that through a smart tablet device and touch screen sensor technologies could be able to capture detailed information about children’s motor patterns. We compared movement trajectories of autistic children and typically developing children, with the aim to identify autism motor signatures analyzing their coordinates of movements. We used a smart tablet device to record coordinates of dragging movements carried out by 60 children (30 autistic children and 30 typically developing children) during a cognitive task. Machine learning analysis of children’s motor patterns identified autism with 93% accuracy, demonstrating that autism can be computationally identified. The analysis of the features that most affect the prediction reveals and describes the differences between the groups, confirming that motor abnormalities are a core feature of autism.

A multimethod approach to assessing motor skills in boys and girls with autism spectrum disorder

Autism ◽  
2021 ◽  
pp. 136236132199563
Author(s):  
Alessandro Crippa ◽  
Francesco Craig ◽  
Silvia Busti Ceccarelli ◽  
Maddalena Mauri ◽  
Silvia Grazioli ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Adaptive Functioning ◽  
Developmental Coordination Disorder ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Multimethod Approach ◽  
Motor Abnormalities

Motor abnormalities are highly prevalent in children with autism spectrum disorder and are strongly predictive of adaptive functioning. Despite the documented sex bias in the prevalence of the disorder, the impact of sex differences on motor abnormalities has been overlooked. The goal of this study was to investigate differences in the motor profile of boys and girls with autism spectrum disorder aged 3–11 years using a multimethod approach. Ninety-eight children with autism spectrum disorder and 98 typically developing children were assessed using the Movement Assessment Battery for Children 2, the Developmental Coordination Disorder Questionnaire, and the kinematic analysis of a reach-to-drop task. Results from principal components analysis on reach-to-drop-dependent measures indicated four components, accounting for kinematic parameters of the motor task. Irrespective of sex, children with autism spectrum disorder showed worse scores on Movement Assessment Battery for Children 2 and Developmental Coordination Disorder Questionnaire subscales than typically developing children. Interestingly, a diagnosis-by-sex interaction was found on a kinematic feature measured in the last part of the movement, with girls with autism spectrum disorder presenting altered motor anticipation. Although preliminary, these findings suggested that sex-related nuances in motor functioning of children with autism spectrum disorder could be insufficiently captured by existing motor measures. Lay abstract Motor peculiarities are often reported in children with autism spectrum disorder and may predict subsequent adaptive functioning and quality of life. Although the sex bias in the prevalence of the disorder is well documented, little is known about differences in motor profile in males and females with autism spectrum disorder. Our goal was to study differences in motor functioning of boys and girls with autism spectrum disorder aged 3–11 years compared with typically developing children. Their motor performances were evaluated using a multimethod approach, including standardized motor tests, caregiver reports, and a detailed motion capture analysis of a simple reach-to-drop movement. We found that, irrespective of sex, children with autism spectrum disorder had worse scores than typically developing children on standardized tests and on caregiver reports. Interestingly, girls with autism spectrum disorder, but not boys, presented altered motor anticipation in reach-to-drop. Our findings emphasize the need for more sex-specific assessment of motor function in autism spectrum disorder.

Neural substrates of a schizotypal spectrum in typically-developing children: Further evidence of a normal-pathological continuum

2016 ◽  
Vol 315 ◽  
pp. 141-146 ◽  
Author(s):  
David W. Evans ◽  
Andrew M. Michael ◽  
Mirko Ularević ◽  
Laina G. Lusk ◽  
Julia M. Buirkle ◽  
...  
Keyword(s):  
Neural Substrates ◽  
Typically Developing ◽  
Typically Developing Children

Design of a Novel Mobility Interface for Infants on a Mobile Robot by Kicking

2010 ◽  
Vol 4 (3) ◽  
Author(s):  
Xi Chen ◽  
Sherry Liang ◽  
Stephen Dolph ◽  
Christina B. Ragonesi ◽  
James C. Galloway ◽  
...  
Keyword(s):  
Typically Developing ◽  
Social And Emotional Development ◽  
Independent Mobility ◽  
Typically Developing Children ◽  
Future Studies ◽  
Mobility Impairments ◽  
Social And Emotional ◽  
Current Medical Practice ◽  
Using Data

Many infants with special needs, such as with Down syndrome, cerebral palsy, and autism have delayed independent mobility due to weak musculature and/or poor coordination. Children with mobility impairments often do not use powered chairs until the age of five, as per current medical practice. Consequently, these children spend considerably less time moving independently around in their environment compared with typically developing children of the same age. Lack of independent mobility may result in delays in their cognitive, perceptual, social, and emotional development, which are well correlated with locomotion. This paper describes a novel mobility interface for the robot to explore the environment when infants are placed in a prone position. Infants can maneuver the robot through a drive interface that utilizes a camera to detect the motion of markers attached to their legs. We expect that infants will learn to drive the device by swinging their legs. Specifically, this paper demonstrates feasibility of this drive interface using data from two infants. Future studies will determine how infants can be trained to drive a robot purposefully and how such self-generated locomotion affects their long-term development.

Age Norms for Auditory-Perceptual Neurophonetic Parameters: A Prerequisite for the Assessment of Childhood Dysarthria

2020 ◽  
Vol 63 (4) ◽  
pp. 1071-1082
Author(s):  
Theresa Schölderle ◽  
Elisabet Haas ◽  
Wolfram Ziegler
Keyword(s):  
Assessment Tool ◽  
Developmental Trajectories ◽  
Voice Quality ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Age Norms ◽  
Elementary School Age ◽  
Speech Characteristics ◽  
Substantial Progress ◽  
Computer Based

Purpose The aim of this study was to collect auditory-perceptual data on established symptom categories of dysarthria from typically developing children between 3 and 9 years of age, for the purpose of creating age norms for dysarthria assessment. Method One hundred forty-four typically developing children (3;0–9;11 [years;months], 72 girls and 72 boys) participated. We used a computer-based game specifically designed for this study to elicit sentence repetitions and spontaneous speech samples. Speech recordings were analyzed using the auditory-perceptual criteria of the Bogenhausen Dysarthria Scales, a standardized German assessment tool for dysarthria in adults. The Bogenhausen Dysarthria Scales (scales and features) cover clinically relevant dimensions of speech and allow for an evaluation of well-established symptom categories of dysarthria. Results The typically developing children exhibited a number of speech characteristics overlapping with established symptom categories of dysarthria (e.g., breathy voice, frequent inspirations, reduced articulatory precision, decreased articulation rate). Substantial progress was observed between 3 and 9 years of age, but with different developmental trajectories across different dimensions. In several areas (e.g., respiration, voice quality), 9-year-olds still presented with salient developmental speech characteristics, while in other dimensions (e.g., prosodic modulation), features typically associated with dysarthria occurred only exceptionally, even in the 3-year-olds. Conclusions The acquisition of speech motor functions is a prolonged process not yet completed with 9 years. Various developmental influences (e.g., anatomic–physiological changes) shape children's speech specifically. Our findings are a first step toward establishing auditory-perceptual norms for dysarthria in children of kindergarten and elementary school age. Supplemental Material https://doi.org/10.23641/asha.12133380

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