scholarly journals COVID-19 Delta Variants – Current Status and Implications as of August 2021

2021 ◽  
Author(s):  
Flora Yu ◽  
Terence Lok-Ting Lau ◽  
Manson Fok ◽  
Johnson Yiu-Nam Lau ◽  
Kang Zhang
Keyword(s):  
Public Health ◽  
Viral Load ◽  
Amino Acid ◽  
Current Understanding ◽  
Current Status ◽  
Clinical Implications ◽  
Amino Acid Substitutions ◽  
Health Implications ◽  
The Public ◽  
Health Authorities

Abstract The SARS-CoV-2 Delta variant has evolved as the dominant strain of the current pandemic. Studies have shown that this variant has increased infectivity/viral load, and reduced neutralization by the host antibodies from convalescent patients/vaccinees. Clinically, Delta variant infection have been observed/documented in convalescent patients/vaccinees, although with less incidence of severe diseases, but can serve as reservoir to spread the infection to the unvaccinated. The current understanding (as of August 18, 2021) on the virologic aspect (including the amino acid substitutions), clinical implications, and the public health implications will be discussed in this review, and recommendations to health authorities will be provided.

Understanding the Public Health Implications of Prisoner Reentry in California: Summary

2009 ◽  
Author(s):  
Lois M. Davis ◽  
Nancy Nicosia ◽  
Adrian Overton ◽  
Lisa Miyashiro ◽  
Kathryn Pitkin Derose ◽  
...  
Keyword(s):  
Public Health ◽  
Prisoner Reentry ◽  
Health Implications ◽  
The Public

scholarly journals The public health implications of urban dogs.

1975 ◽  
Vol 65 (12) ◽  
pp. 1315-1318 ◽  
Author(s):  
A M Beck
Keyword(s):  
Public Health ◽  
Health Implications ◽  
The Public

scholarly journals Prototypical Recombinant Multi-Protease-Inhibitor-Resistant Infectious Molecular Clones of Human Immunodeficiency Virus Type 1

2013 ◽  
Vol 57 (9) ◽  
pp. 4290-4299 ◽  
Author(s):  
Vici Varghese ◽  
Yumi Mitsuya ◽  
W. Jeffrey Fessel ◽  
Tommy F. Liu ◽  
George L. Melikian ◽  
...  
Keyword(s):  
Amino Acid ◽  
Protease Inhibitor ◽  
Cross Resistance ◽  
Amino Acid Substitutions ◽  
Phenotypic Properties ◽  
The Public ◽  
Immunodeficiency Virus ◽  
The Many ◽  
High Level ◽  
Infectious Molecular Clones

ABSTRACTThe many genetic manifestations of HIV-1 protease inhibitor (PI) resistance present challenges to research into the mechanisms of PI resistance and the assessment of new PIs. To address these challenges, we created a panel of recombinant multi-PI-resistant infectious molecular clones designed to represent the spectrum of clinically relevant multi-PI-resistant viruses. To assess the representativeness of this panel, we examined the sequences of the panel's viruses in the context of a correlation network of PI resistance amino acid substitutions in sequences from more than 10,000 patients. The panel of recombinant infectious molecular clones comprised 29 of 41 study-defined PI resistance amino acid substitutions and 23 of the 27 tightest amino acid substitution clusters. Based on their phenotypic properties, the clones were classified into four groups with increasing cross-resistance to the PIs most commonly used for salvage therapy: lopinavir (LPV), tipranavir (TPV), and darunavir (DRV). The panel of recombinant infectious molecular clones has been made available without restriction through the NIH AIDS Research and Reference Reagent Program. The public availability of the panel makes it possible to compare the inhibitory activities of different PIs with one another. The diversity of the panel and the high-level PI resistance of its clones suggest that investigational PIs active against the clones in this panel will retain antiviral activity against most if not all clinically relevant PI-resistant viruses.

scholarly journals The public health implications of farming cattle in areas with high background concentrations of vanadium

2005 ◽  
Vol 72 (3-4) ◽  
pp. 281-290 ◽  
Author(s):  
B. Gummow ◽  
C.J. Botha ◽  
J.P.T.M. Noordhuizen ◽  
J.A.P. Heesterbeek
Keyword(s):  
Public Health ◽  
Background Concentrations ◽  
High Background ◽  
Health Implications ◽  
The Public

The Public Health Police

2017 ◽  
Author(s):  
Trevor Hoppe
Keyword(s):  
Public Health ◽  
Hiv Positive ◽  
Local Health ◽  
Health Departments ◽  
Adherence To Treatment ◽  
The Public ◽  
Treatment Regimens ◽  
Health Authorities ◽  
Public Health Authorities ◽  
Local Health Authorities

As the HIV epidemic wore on in the 2000s, public health authorities became enamored with the idea of “ending AIDS.” That is, if they could just get HIV-positive people to take their pills and stop infecting other people. Health departments began to track HIV-positive clients more closely, aiming to control their behavior and ensure their adherence to treatment regimens. This chapter explores how local health authorities ensure that HIV-positive clients behave in a manner officials deem responsible—and how they catch and punish those who do not. While the state maintains that the work of local health officials is done solely in the interests of promoting public health, their efforts to control HIV-positive clients reveal that they are also engaged in policing and law enforcement.

Establishing connection among all through blood donation: Current status and public health implications

2017 ◽  
Vol 10 (5) ◽  
pp. 1357 ◽  
Author(s):  
SaurabhR Shrivastava ◽  
PrateekS Shrivastava ◽  
Jegadeesh Ramasamy
Keyword(s):  
Public Health ◽  
Blood Donation ◽  
Current Status ◽  
Health Implications

What are the public health implications of subclinical depressive symptoms?

1994 ◽  
Vol 65 (4) ◽  
pp. 323-337 ◽  
Author(s):  
Ewald Horwath ◽  
Jim Johnson ◽  
Gerald L. Klerman ◽  
Myrna M. Weissman
Keyword(s):  
Public Health ◽  
Depressive Symptoms ◽  
Health Implications ◽  
The Public

scholarly journals Rational trust in resilient health systems

2019 ◽  
Vol 34 (7) ◽  
pp. 553-557 ◽  
Author(s):  
Sonja Kristine Kittelsen ◽  
Vincent Charles Keating
Keyword(s):  
Public Health ◽  
Health System ◽  
Health Systems ◽  
The Public ◽  
Public Health Emergencies ◽  
Health Authorities ◽  
Cast Doubt ◽  
Public Health Authorities ◽  
System Resilience ◽  
Relevant Component

AbstractThe 2014–15 Ebola epidemic in West Africa highlighted the significance of trust between the public and public health authorities in the mitigation of health crises. Since the end of the epidemic, there has been a focus amongst scholars and practitioners on building resilient health systems, which many see as an important precondition for successfully combatting future outbreaks. While trust has been acknowledged as a relevant component of health system resilience, we argue for a more sustained theoretical engagement with underlying models of trust in the literature. This article takes a first step in showing the importance of theoretical engagement by focusing on the appeal to rational models of trust in particular in the health system resilience literature, and how currently unconsidered assumptions in this model cast doubt on the effectiveness of strategies to generate trust, and therein resilience, during acute public health emergencies.

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