A structural role of histidine 15 in human glutathione transferase M1-1, an amino acid residue conserved in class Mu enzymes

1992 ◽  
Vol 5 (6) ◽  
pp. 551-557 ◽  
Author(s):  
Mikael Widersten ◽  
Bengt Mannervik
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue ◽  
Glutathione Transferase ◽  
Structural Role

scholarly journals The Unusual Role of Pro in Cu(II) Binding by His2-Cyclopentapeptide

2021 ◽  
Vol 22 (12) ◽  
pp. 6628
Author(s):  
Aleksandra Pieniężna ◽  
Aleksandra Kotynia ◽  
Justyna Brasuń
Keyword(s):  
Amino Acid ◽  
Potentiometric Titration ◽  
Amino Acid Residue ◽  
Strong Impact ◽  
Mononuclear Complexes ◽  
Study Results ◽  
Metal Ratio ◽  
Ph Range ◽  
L1 And L2

In this paper, we present findings from studying the interaction of copper(II) ions with the His2-cyclopentapeptide and the role of proline used for the purpose of potentiometric titration and UV-Vis, CD and EPR spectroscopic measurements. Experiments of two homodetic peptides differing by one amino acid residue were conducted for a ligand to metal ratio of 1:1 in the pH range 2.5–11.0. The presented studies reveal that peptides form only mononuclear complexes, and the CuH2L complex appears in the system first (for both L1 and L2). Study results show that the presence of Pro influences the structure of formed complexes and their stabilities and has a strong impact on the efficiency of copper(II) coordination.

Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants

2007 ◽  
Vol 1774 (8) ◽  
pp. 1029-1035 ◽  
Author(s):  
Hiroko Shibata ◽  
Haruhiko Kamada ◽  
Kyoko Kobayashi-Nishibata ◽  
Yasuo Yoshioka ◽  
Toshihide Nishibata ◽  
...  
Keyword(s):  
Amino Acid ◽  
Tumor Necrosis Factor ◽  
Receptor Binding ◽  
Amino Acid Residue ◽  
Tumor Necrosis ◽  
Binding Capacity ◽  
Necrosis Factor

Role of Amino Acid Residue 187 of Poliovirus Polypeptide 2C in Determining the Guanidine Trait

Intervirology ◽  
1992 ◽  
Vol 33 (3) ◽  
pp. 165-172 ◽  
Author(s):  
Robert F. Baltera Jr. ◽  
Daniel R. Tershak
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue

Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding

FEBS Journal ◽  
2005 ◽  
Vol 272 (15) ◽  
pp. 3960-3966 ◽  
Author(s):  
Zhengding Su ◽  
Jiun-Ming Wu ◽  
Huey-Jen Fang ◽  
Tian-Yow Tsong ◽  
Hueih-Min Chen
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue ◽  
Aromatic Amino Acid ◽  
Local Stability ◽  
Staphylococcal Nuclease ◽  
Aromatic Amino Acid Residue

scholarly journals The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model

2015 ◽  
Vol 11 (7) ◽  
pp. e1005033 ◽  
Author(s):  
Chikako Kataoka ◽  
Tadaki Suzuki ◽  
Osamu Kotani ◽  
Naoko Iwata-Yoshikawa ◽  
Noriyo Nagata ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue ◽  
Cynomolgus Monkey ◽  
Enterovirus 71 ◽  
Viral Fitness ◽  
Monkey Model
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