Complementary and Integrative Health Interventions for Insomnia in Veterans and Military Populations

Insomnia can be a serious problem diminishing quality of life for Veterans and military populations with and without posttraumatic stress disorder (PTSD). Sleep disturbances are one of the symptoms of PTSD but even after evidence-based PTSD treatments, insomnia symptoms often remain. The primary approaches for treating insomnia are cognitive behavioral therapy for insomnia (CBT-I) and pharmacotherapy. However, each of these treatments has drawbacks. Complementary and Integrative Health (CIH) approaches such as mindfulness meditation, mantram meditation, yoga, and tai chi may provide alternative treatments for insomnia in military populations. This paper provides a brief review of studies on CIH interventions for sleep disturbances in Veterans. It also proposes possible mechanisms by which CIH practices may be effective, including increasing hippocampal volume and gamma-aminobutyric acid acid (GABA). Finally, the acceptability of CIH approaches among Veterans is discussed.

Effect of Aggravated Temperature on Indicators of Oxidative Texture of Canned Meat

The article presents experimental data on the study of the processes of oxidative spoilage of fat in sterilized canned meat when stored under temperature conditions of + 37 ° C. The intensity of oxidative processes is estimated indirectly by the accumulation of primary and secondary products of fat oxidation. The dynamics of such physical and chemical indicators as thiobarbituric acid, acid, peroxide numbers, active and titratable acidity is considered.

Cocrystals Based on 4,4’-bipyridine: Influence of Crystal Packing on Melting Point

The reactions of piperonylic acid (HPip) and cinnamic acid (HCinn) with 4,4’-bipyridine (4,4’-bipy) have been assayed using the same synthetic methodology, yielding two binary cocrystals with different acid:4,4’-bipy molar ratios, (HPip)(4,4’-bipy) (1) and (HCinn)2(4,4’-bipy) (2). The melting point (m.p.) of these cocrystals have been measured and a remarkable difference (ΔT ≈ 78 °C) between them was observed. Moreover, the two cocrystals have been characterized by powder X-ray diffraction (PXRD), elemental analysis (EA), FTIR-ATR, 1H NMR spectroscopies, and single-crystal X-ray diffraction. The study of their structural packings via Hirshfeld surface analysis and energy frameworks revealed the important contribution of the π···π and C-H···π interactions to the formation of different structural packing motifs, this being the main reason for the difference of m.p. between them. Moreover, it has been observed that 1 and 2 presented the same packing motifs as the crystal structure of their corresponding carboxylic acids, but 1 and 2 showed lower m.p. than those of the carboxylic acids, which could be related to the lower strength of the acid-pyridine heterosynthons respect to the acid-acid homosynthons in the crystal structures.

Crystal structure from laboratory X-ray powder diffraction data, DFT-D calculations, Hirshfeld surface analysis, and energy frameworks of a new polymorph of 1-benzothiophene-2-carboxylic acid

Several benzothiophene-based compounds, including 1-benzothiophene-2-carboxylic acid, exhibit a wide variety of pharmacological activities. They have been extensively used to treat various types of diseases with high therapeutic effectiveness. In this contribution, the crystal structure of a new polymorph of 1-benzothiophene-2-carboxylic acid (BTCA) was determined from laboratory X-ray powder diffraction data with DASH, refined by the Rietveld method with TOPAS-Academic, and optimized using DFT-D calculations. The new form of 1-benzothiophene-2-carboxylic acid crystallizes in space group C2/c (No. 15) with a = 14.635(4), b = 5.8543(9), c = 19.347(3) Å, β = 103.95(1)°, V = 1608.8(6) Å3, and Z = 8. The structure is a complex 3D arrangement which can be described in terms of hydrogen-bonded dimers of BTCA molecules, joined by the acid–acid homosynthon, which interact through C–H⋯O hydrogen bonds to produce tapes further connected through head-to-tail π⋯π and edge-to-face C–H⋯π interactions. A comparison with a previously reported triclinic polymorph and with the related 1-benzofuran-2-carboxylic acid (BFCA) is also presented.

Vinegar production from Theobroma grandiflorum SCHUM (cupuassu)

<abstract> <p>The tropical fruit cupuassu comes from <italic>Theobroma grandiflorum</italic> (SCHUM), a close relative of cocoa. Cupuassu has a rich yet delicate flavour profile with notes of chocolate, pineapple, passion fruit and other fruits. Here, we produced a cupuassu-fruit wine using a Saccharomyces cerevisiae inoculum (and univariate analysis to determine conditions for optimum ethanol production) and then fermented this wine to produce a delicate and unique cupuassu vinegar using acid-acid bacteria. The cupuassu wine was produced by fermentation of juice chaptalized with sucrose, with a final ethanol concentration of 10% (v/v). Acetic-acid fermentations were carried out in both a bubble-column reactor and a mechanically non-aerated reactor (high-surface reactor), producing final concentrations of 4.5 and 3.3% (w/v) acetic acid, respectively. The ethanol- and acetic-acid yields obtained were comparable to those of other fruit wines and fruit vinegars. The cupuassu vinegar retained the rich flavor profile of the cupuassu. We believe that the production of flavorsome products from local plants can have benefits for conservation by promoting ecologically sustainable agriculture and may contribute to cultural identity of Amazon people.</p> </abstract>

Suitable acid groups and density in electrolytes to facilitate proton conduction

Proton conducting materials suffer from low proton conductivity under low-relative humidity (RH) conditions. Previously, it was reported that acid-acid interactions, where acids interact with each other at close distances, can...

STUDY OF PHENOLIC COMPOUNDS IN THE ABOVE-GROUND PART OF CERTAIN SPECIES OF THE GENUS INULA BY HPLC

Studied the cоmpоsitiоn оf phenоlic cоmpоunds cоntained in the aerial part оf wild plants оf the genus Inula, cоllected in different areas оf the Nоrthern Caucasus (Inula оrientalis, Inula salicina, Inula germanica). The HPLC methоd identified 20 phenоlic cоmpоunds in the aerial part оf the Inula оrientalis, identified 17 cоmpоunds (tannin, galic acid, chlоrоgenic acid, chicоreic acid, ferulic acid and оther cоmpоunds), in the aerial part оf the Inula aspera, 19 cоmpоunds оf phenоlic nature were fоund, 12 cоmpоunds were identified (dihydrоcоumarin, hyperоside, galic acid, chlоrоgenic acid, and оther cоmpоunds), in the aerial part оf the Inula germanica, 22 phenоlic cоmpоunds were fоund, 14 cоmpоunds were identified (dihydrоcоumarin, hyperоside, rutin, chlоrоgenic acid, and оther cоmpоunds). The study оf the qualitative cоmpоsitiоn оf phenоlic cоmpоunds was carried оut оn a high-perfоrmance liquid chrоmatоgraph оf the firm "GILSTОN", mоdel 305, FRANCE; manual injectоr, mоdel RHEОDYNE 7125 USA, fоllоwed by cоmputer prоcessing оf the research results using the Multichrоm prоgram fоr Windоws. The system - methanol - water - concentrated phosphoric acid - tetrahydrofuran, in the ratio 370: 570: 5: 60 was chosen as the mobile phase. The stationary phase was a 4.6 x 250 mm KROMASIL C18 metal column with a particle size of 5 microns. According to the method, the analysis was carried out at room temperature. The flow rate of the eluent is 0.8 ml / min. Analysis duration 60 min. Detectiоn was carried оut using a GILSTОN UV/VIS mоdel 151 UV detectоr at a wavelength оf 254 nm. Fоr research, crushed plant material tо a particle size passing thrоugh a sieve with a hоle diameter оf 2 mm was placed in a flask with a capacity оf 100 ml, 20 ml оf 70% ethyl alcоhоl was added, attached tо a reflux cоndenser and heated in a bоiling water bath fоr 1 hоur frоm the mоment the alcоhоl-water mixture bоiled in the flask. After cооling, the mixture was filtered thrоugh a paper filter intо a 25 ml vоlumetric flask and diluted with ethyl alcоhоl 70% up tо the mark. In parallel, a series оf 0.05% reference sоlutiоns in 70% ethyl alcоhоl was prepared: cinnamic acid, chicoric acid, ferulic acid, tannin, epicatechin, catechin, naringenin, dicoumarin, dihydroquercetin, rutin, quercetin, luteolin, luteolin-7-glycoside, kaempferol, coumarin, hyperoside, hesperidin, apigenin, gallic acid acid, neochlorogenic acid.