scholarly journals Effect of Route of Inoculation on Humoral Immune Response of White Leghorn Chickens Selected for High or Low Antibody Response to Sheep Red Blood Cells

2001 ◽  
Vol 80 (8) ◽  
pp. 1073-1078 ◽  
Author(s):  
K. Boa-Amponsem ◽  
S.E.H. Price ◽  
E.A. Dunnington ◽  
P.B. Siegel
Keyword(s):  
Immune Response ◽  
Antibody Response ◽  
Red Blood Cells ◽  
Humoral Immune Response ◽  
Blood Cells ◽  
White Leghorn ◽  
Humoral Immune ◽  
Sheep Red Blood Cells

scholarly journals Investigation of the immune status of mice during and following selective decontamination of the digestive tract

1989 ◽  
Vol 103 (2) ◽  
pp. 323-332 ◽  
Author(s):  
A. B. J. Speekenbrink ◽  
S. R. Alcock ◽  
D. M. V. Parrott
Keyword(s):  
Immune Response ◽  
Antibody Response ◽  
Red Blood Cells ◽  
Digestive Tract ◽  
Blood Cells ◽  
Cellular Response ◽  
Intensive Therapy ◽  
Selective Decontamination ◽  
Protein Antigens ◽  
Sheep Red Blood Cells

SUMMARYSelective decontamination of the digestive tract (SDD) employs oral antibiotics to eliminate aerobic Gram-negative bacilli while retaining the anaerobic flora. A combination of SDD and parenteral cefotaxime has recently been reported to strikingly reduce the incidence of infection in patients treated in an intensive therapy unit. The present study describes the effects of SDB and of cefotaxime on the immune response of mice to protein antigens. The in vivo cellular response to ovalbumin and sheep red blood cells was unchanged. However, SDD appeared to decrease the in vitro mitogenic response of spleen cells to phytohaemagglutinin, and cefotaxime similarly affected the response to Concanavalin A. The antibody response to sheep red blood cells was increased in the period after discontinuation of SDD. The antibody response was otherwise not affected. These results indicate that SDD is unlikely to have adverse effects on the immune response to protein antigens.

B.C.L. and Immune Response in Mice

1986 ◽  
Vol 14 (01n02) ◽  
pp. 33-36
Author(s):  
G.M. Sein ◽  
M. Phil
Keyword(s):  
Immune Response ◽  
Herbal Medicine ◽  
Red Blood Cells ◽  
Concanavalin A ◽  
Humoral Immune Response ◽  
Blood Cells ◽  
Parent Compound ◽  
Lymphocyte Transformation ◽  
Immunological Response ◽  
Humoral Immune

The effects of Korean herbal medicine (B.C.L.) on some parametrs of immunological response were studied in mice, B.C.L. pretreatment given either intraperitoneally subcutaneously in a dose of 0.75 mg/mouse did not significantly inhibit lymphocyte transformation induced by concanavalin A. However, B.C.L. pretreatment in a dose of 2.25 mg/mouse was found to reduce significantly both the plaque-forming cells to sheep red blood cells immunisation as well as total splee cell population. Thus, B.C.L. pretreatment with a higher does (2.25 mg/mouse) can selectively depress the humoral immune response. It is unclear, however, whether this action is mediated by the parent compound or its metabolities.

Sign in / Sign up

Export Citation Format

Share Document