scholarly journals Disseminated BCG Infection after intravesical BCG Immunotherapy of Bladder Cancer

QJM ◽  
2021 ◽  
Author(s):  
S Ramalingam ◽  
K Gunasekaran ◽  
H Arora ◽  
M Muruganandam ◽  
S Nagaraju ◽  
...  
1993 ◽  
Vol 150 (3) ◽  
pp. 1018-1023 ◽  
Author(s):  
Timothy L. Ratliff ◽  
Julie K. Ritchey ◽  
Jerry J.J. Yuan ◽  
Gerald L. Andriole ◽  
William J. Catalona

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Yuqing Liu ◽  
Jian Lu ◽  
Yi Huang ◽  
Lulin Ma

Because of its proven efficacy, intravesical Bacillus Calmette-Guérin (BCG) immunotherapy is an important treatment for nonmuscle invasive bladder cancer at high risk of recurrence or progression. However, approximately 8% of patients have to stop BCG instillation as a result of its complications. Complications induced by BCG therapy can have a variety of clinical manifestations. These adverse reactions may occur in conjunction with BCG instillation or may not develop until months or years after BCG cessation. An essential step in the management complications arising from BCG is early establishment of diagnosis, particularly for distant, disseminated, and obscure infections. Therefore we reviewed the literature on the potential complications after intravesical BCG immunotherapy for bladder cancer and provide an overview on the incidence, diagnosis, and treatment modality of genitourinary and systemic BCG-induced complications.


Author(s):  
Artur Chmiel ◽  
Joanna Wierzbicka-Chmiel ◽  
Krzysztof Wierzbicki ◽  
Tadeusz Dzielski ◽  
Jolanta Gil

2011 ◽  
Vol 22 (3) ◽  
pp. 104-106 ◽  
Author(s):  
Vitaly Golub ◽  
Prashant Malhotra ◽  
Shital Patel

Bacille Calmette-Guérin (BCG) immunotherapy is widely used for the treatment of superficial bladder cancer. The authors believe that the present report is one of the first to document cerebral BCG tuberculoma in a 73-year-old immunocompetent man, three years after intra-vesical BCG immunotherapy. His workup revealed no identifiable extracranial source. He responded well to treatment with rifampin, ethambutol and moxifloxacin.Patients undergoing intravesical BCG therapy should be closely monitored for the development of this complication. Prolonged antitubercular therapy, possibly including moxifloxacin, appears to be beneficial in the treatment of central nervous system tuberculous infections.


Radiographics ◽  
2019 ◽  
Vol 39 (1) ◽  
pp. 80-94 ◽  
Author(s):  
Daniel B. Green ◽  
Akira Kawashima ◽  
Christine O. Menias ◽  
Takashi Tanaka ◽  
Gil Redelman-Sidi ◽  
...  

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