scholarly journals An Evaluation of Estrogenic Activity of Parabens Using Uterine Calbindin-D9k Gene in an Immature Rat Model

2009 ◽  
Vol 112 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Thuy T. B. Vo ◽  
Eui-Bae Jeung
Keyword(s):  
Rat Model ◽  
Estrogenic Activity ◽  
Immature Rat ◽  
Calbindin D9k

Distribution of and steroid hormone effects on calbindin-D9k in the immature rat brain

2019 ◽  
Author(s):  
Seon Mi Park ◽  
Seon Young Park ◽  
Dinh Nam Tran ◽  
Eui-Bae Jeung
Keyword(s):  
Rat Brain ◽  
Steroid Hormone ◽  
Immature Rat ◽  
Calbindin D9k ◽  
Hormone Effects

Distribution of and steroid hormone effects on calbindin-D9k in the immature rat brain

2019 ◽  
Vol 152 ◽  
pp. 225-235
Author(s):  
Seon Young Park ◽  
Yeong-Min Yoo ◽  
Eui-Man Jung ◽  
Eui-Bae Jeung
Keyword(s):  
Rat Brain ◽  
Steroid Hormone ◽  
Immature Rat ◽  
Calbindin D9k ◽  
Hormone Effects

Diosgenin does not express estrogenic activity: a uterotrophic assay

2014 ◽  
Vol 92 (4) ◽  
pp. 292-298 ◽  
Author(s):  
Ivana Medigović ◽  
Nataša Ristić ◽  
Jasmina Živanović ◽  
Branka Šošić-Jurjević ◽  
Branko Filipović ◽  
...  
Keyword(s):  
Estrogen Receptor Alpha ◽  
Estrogenic Activity ◽  
Female Rats ◽  
Control Group ◽  
Immunohistochemical Expression ◽  
Vehicle Control Group ◽  
Immature Rat ◽  
Intact Control ◽  
Uterotrophic Assay ◽  
Wet Weight

This study assessed the effects of diosgenin on estrogenic activity using a uterotrophic assay. Immature female rats received diosgenin orally at doses of 200, 100, or 20 mg/kg body mass; and 17α ethynylestradiol at doses of 1 or 0.3 μg/kg, daily, for 3 consecutive days from day 19 to day 21. Controls were distributed among 2 groups: an intact control group and a vehicle control group. Animals were sacrificed 24 h after the last application of diosgenin, estradiol, or vehicle (22nd day of life). Uterine wet weight, stereological and histomorphometrical changes, immunohistochemical expression of estrogen receptor alpha (ERα), progesterone receptor (PR), and the expression of lactoferrin (LF) were examined. Diosgenin did not affect the uterine wet weight, epithelium height, volume densities of endometrium, endometrial epithelia, number of endometrial glands, or histological appearance of vaginal epithelia. ERα, PR, and LF immunostaining intensity were not altered in the animals that received diosgenin. High-potency reference ER agonist 17α-ethynylestradiol induced a significant increase in all of the measured parameters, and as expected, decreased ERα immunostaining intensity. Based on these data, it can be concluded that diosgenin, at doses of 20–200 mg/kg, did not act as an estrogen agonist in the immature rat uterotrophic assay.

scholarly journals Insights into the role of iron in immature rat model of hypoxic-ischemic brain injury

2016 ◽  
Vol 12 (3) ◽  
pp. 1723-1731
Author(s):  
Zi-Wei Wang ◽  
Li-Jun Yang ◽  
Ying-Xue Ding ◽  
Yan-Zhong Chang ◽  
Hong Cui
Keyword(s):  
Brain Injury ◽  
Rat Model ◽  
Ischemic Brain Injury ◽  
Immature Rat ◽  
Ischemic Brain ◽  
Hypoxic Ischemic Brain Injury

An Evaluation of Estrogenic Activity of Parabens Using Uterine Calbindin-D9k Gene in Rat Models.

2009 ◽  
Vol 81 (Suppl_1) ◽  
pp. 253-253
Author(s):  
Thuy T.B. Vo ◽  
Eui-Bae Jeung
Keyword(s):  
Estrogenic Activity ◽  
Rat Models ◽  
Calbindin D9k

scholarly journals Ginkgo biloba extract (EGb761) did not express estrogenic activity in an immature rat uterotrophic assay

2018 ◽  
Vol 33 (3) ◽  
pp. e2018016
Author(s):  
Byeonghak Moon ◽  
Wonchan Kim ◽  
Cho Hee Park ◽  
Seung Min Oh
Keyword(s):  
Ginkgo Biloba ◽  
Estrogenic Activity ◽  
Ginkgo Biloba Extract ◽  
Immature Rat ◽  
Uterotrophic Assay

scholarly journals Cerebral Glucose Metabolism in an Immature Rat Model of Pediatric Traumatic Brain Injury

2013 ◽  
Vol 30 (24) ◽  
pp. 2066-2072 ◽  
Author(s):  
Courtney L. Robertson ◽  
Manda Saraswati ◽  
Susanna Scafidi ◽  
Gary Fiskum ◽  
Paula Casey ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Glucose Metabolism ◽  
Rat Model ◽  
Cerebral Glucose Metabolism ◽  
Pediatric Traumatic Brain Injury ◽  
Immature Rat
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