scholarly journals Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis

2015 ◽  
Vol 149 (2) ◽  
pp. 396-410 ◽  
Author(s):  
Banrida Wahlang ◽  
Russell A. Prough ◽  
K. Cameron Falkner ◽  
Josiah E. Hardesty ◽  
Ming Song ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Nuclear Receptor ◽  
Polychlorinated Biphenyl ◽  
Alcoholic Steatohepatitis ◽  
Receptor Interactions ◽  
Regulate Energy Metabolism

Analysis of Chromatin–Nuclear Receptor Interactions by Laser-Chromatin Immunoprecipitation

2014 ◽  
pp. 25-34 ◽  
Author(s):  
Rosaria Benedetti ◽  
Mariarosaria Conte ◽  
Vincenzo Carafa ◽  
Bartolomeo Della Ventura ◽  
Carlo Altucci ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Chromatin Immunoprecipitation ◽  
Receptor Interactions

scholarly journals Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

2016 ◽  
Vol 5 (4) ◽  
pp. 283-295 ◽  
Author(s):  
Torsten Schröder ◽  
David Kucharczyk ◽  
Florian Bär ◽  
René Pagel ◽  
Stefanie Derer ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Gene Polymorphisms ◽  
Mitochondrial Gene ◽  
Cellular Energy ◽  
Cellular Energy Metabolism ◽  
Alcoholic Steatohepatitis

scholarly journals MDM2 ubiquitin-ligase down-regulate energy metabolism of cancer cells

2019 ◽  
Vol 35 (3) ◽  
pp. 233-233
Author(s):  
O. Shuvalov ◽  
A. Petukhov ◽  
O. Fedorova ◽  
A. Daks ◽  
E. Baidyuk ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Cancer Cells ◽  
Ubiquitin Ligase ◽  
Regulate Energy Metabolism

Integrative transcriptomics and metabolomics explore the mechanism of kaempferol on improving nonalcoholic steatohepatitis

2020 ◽  
Vol 11 (11) ◽  
pp. 10058-10069
Author(s):  
Yifei Lu ◽  
Mingmei Shao ◽  
Hongjiao Xiang ◽  
Peiyong Zheng ◽  
Tao Wu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Metabolism ◽  
Energy Metabolism ◽  
Nonalcoholic Steatohepatitis ◽  
Alcoholic Steatohepatitis ◽  
Integration Analysis

By integration analysis of transcriptomics and metabolomics, Kaempferol was found to improve non-alcoholic steatohepatitis in mice probably through regulating energy metabolism, lipid metabolism, oxidative stress and inflammation-related pathways.

scholarly journals Challenges Predicting Ligand-Receptor Interactions of Promiscuous Proteins: The Nuclear Receptor PXR

2009 ◽  
Vol 5 (12) ◽  
pp. e1000594 ◽  
Author(s):  
Sean Ekins ◽  
Sandhya Kortagere ◽  
Manisha Iyer ◽  
Erica J. Reschly ◽  
Markus A. Lill ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Receptor Interactions

Neurotransmitters Regulate Energy Metabolism in Astrocytes: Implications for the Metabolic Trafficking between Neural Cells

1993 ◽  
Vol 15 (3-5) ◽  
pp. 306-312 ◽  
Author(s):  
Pierre J. Magistretti ◽  
Olivier Sorg ◽  
Naichen Yu ◽  
Jean-Luc Martin ◽  
Luc Pellerin
Keyword(s):  
Energy Metabolism ◽  
Neural Cells ◽  
Regulate Energy Metabolism

scholarly journals Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

The Lancet ◽  
2015 ◽  
Vol 385 (9972) ◽  
pp. 956-965 ◽  
Author(s):  
Brent A Neuschwander-Tetri ◽  
Rohit Loomba ◽  
Arun J Sanyal ◽  
Joel E Lavine ◽  
Mark L Van Natta ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Controlled Trial ◽  
Obeticholic Acid ◽  
Receptor Ligand ◽  
Alcoholic Steatohepatitis

Adaptive regulation of glucose transport, glycolysis and respiration for cell proliferation

2015 ◽  
Vol 6 (5-6) ◽  
pp. 423-430 ◽  
Author(s):  
Yusuke Toyoda ◽  
Shigeaki Saitoh
Keyword(s):  
Cell Proliferation ◽  
Energy Metabolism ◽  
Glucose Transport ◽  
Neurodegenerative Disorders ◽  
Human Diseases ◽  
Molecular Regulation ◽  
Adaptive Regulation ◽  
Metabolism Regulation ◽  
Recent Advances ◽  
Regulate Energy Metabolism

AbstractThe cell must utilise nutrients to generate energy as a means of sustaining its life. As the environment is not necessarily abundant in nutrients and oxygen, the cell must be able to regulate energy metabolism to adapt to changes in extracellular and intracellular conditions. Recently, several key regulators of energy metabolism have been reported. This review describes the recent advances in molecular regulation of energy metabolism, focusing mainly on glycolysis and its shunt pathways. Human diseases, such as cancer and neurodegenerative disorders, are also discussed in relation to failure of energy metabolism regulation.

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