Metabolic Reprogramming of the Retinal Pigment Epithelium Drives TGFβ2‐Induced Epithelial‐Mesenchymal Transition

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.03272 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Daisy Shu ◽

Erik Butcher ◽

Siwei Cai ◽

Ilakya Senthilkumar ◽

Scott Frank ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Metabolic Reprogramming ◽

Mesenchymal Transition

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Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium

Redox Biology ◽

10.1016/j.redox.2021.101921 ◽

2021 ◽

Vol 41 ◽

pp. 101921

Author(s):

Kohei Homma ◽

Eriko Toda ◽

Hideto Osada ◽

Norihiro Nagai ◽

Takumi Era ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Induced Pluripotent Stem Cells ◽

Pluripotent Stem Cells ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition ◽

Induced Pluripotent ◽

Metabolic Impairments

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MicroRNA-124 regulates transforming growth factorβ1-induced epithelial-mesenchymal transition in the retinal pigment epithelium by Down-regulating expression of the RhoG

Acta Ophthalmologica ◽

10.1111/j.1755-3768.2015.0289 ◽

2015 ◽

Vol 93 ◽

pp. n/a-n/a

Author(s):

J.H. Jun ◽

C.K. Joo

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition ◽

Microrna 124 ◽

Transforming Growth Factorβ1

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The Complex Interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch Signaling Pathways in the Regulation of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Cells

PLoS ONE ◽

10.1371/journal.pone.0096365 ◽

2014 ◽

Vol 9 (5) ◽

pp. e96365 ◽

Author(s):

Xiaoyun Chen ◽

Wei Xiao ◽

Wencong Wang ◽

Lixia Luo ◽

Shaobi Ye ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Notch Signaling ◽

Signaling Pathways ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Complex Interplay ◽

Mesenchymal Transition ◽

Retinal Pigment Epithelium Cells ◽

Epithelium Cells

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Autophagy regulates TGF-β2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells

Molecular Medicine Reports ◽

10.3892/mmr.2017.8360 ◽

2017 ◽

Author(s):

Jing Wu ◽

Xiaoyun Chen ◽

Xialin Liu ◽

Shan Huang ◽

Chang He ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition ◽

Human Retinal Pigment Epithelium ◽

Retinal Pigment Epithelium Cells ◽

Epithelium Cells

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Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells

Journal of Cellular and Molecular Medicine ◽

10.1111/jcmm.12212 ◽

2014 ◽

Vol 18 (4) ◽

pp. 646-655 ◽

Author(s):

Wei Xiao ◽

Xiaoyun Chen ◽

Xialin Liu ◽

Lixia Luo ◽

Shaobi Ye ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Histone Deacetylase Inhibitor ◽

Epithelial Mesenchymal Transition ◽

Trichostatin A ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition ◽

Deacetylase Inhibitor ◽

Retinal Pigment Epithelium Cells ◽

Epithelium Cells

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LYTAK1, a TAK1 inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells

Molecular Medicine Reports ◽

10.3892/mmr.2016.5275 ◽

2016 ◽

Vol 14 (1) ◽

pp. 145-150 ◽

Author(s):

ZHEN CHEN ◽

YAN MEI ◽

HUO LEI ◽

RUN TIAN ◽

NINGHUA NI ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition ◽

Retinal Pigment Epithelium Cells ◽

Epithelium Cells

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Epithelial–mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy

Histochemistry and Cell Biology ◽

10.1007/s00418-016-1461-4 ◽

2016 ◽

Vol 146 (6) ◽

pp. 769-780 ◽

Author(s):

Andreas Ohlmann ◽

Michael Scholz ◽

Marcus Koch ◽

Ernst R. Tamm

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition

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Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction

Frontiers in Cell and Developmental Biology ◽

10.3389/fcell.2020.00501 ◽

2020 ◽

Vol 8 ◽

Author(s):

Mi Zhou ◽

Jasmine S. Geathers ◽

Stephanie L. Grillo ◽

Sarah R. Weber ◽

Weiwei Wang ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition

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Blockade of Jagged/Notch Pathway Abrogates Transforming Growth Factor β2-Induced Epithelial-Mesenchymal Transition in Human Retinal Pigment Epithelium Cells

Current Molecular Medicine ◽

10.2174/1566524014666140331230411 ◽

2014 ◽

Vol 14 (4) ◽

pp. 523-534 ◽

Author(s):

X. Chen ◽

W. Xiao ◽

X. Liu ◽

M. Zeng ◽

L. Luo ◽

...

Keyword(s):

Growth Factor ◽

Retinal Pigment Epithelium ◽

Transforming Growth Factor ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Notch Pathway ◽

Mesenchymal Transition ◽

Retinal Pigment Epithelium Cells ◽

Epithelium Cells

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Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy

Scientific Reports ◽

10.1038/srep16386 ◽

2015 ◽

Vol 5 (1) ◽

Author(s):

Keijiro Ishikawa ◽

Shikun He ◽

Hiroto Terasaki ◽

Hossein Nazari ◽

Huiming Zhang ◽

...

Keyword(s):

Retinal Pigment Epithelium ◽

Proliferative Vitreoretinopathy ◽

Epithelial Mesenchymal Transition ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Mesenchymal Transition

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