Ablation of optineurin impairs metabotropic glutamate receptor 5 signaling in mouse hippocampus

Karim Ibrahim; Caitlyn McLaren; Khaled Abd‐Elrahman; Stephen Ferguson

doi:10.1096/fasebj.2021.35.s1.03809

Ablation of optineurin impairs metabotropic glutamate receptor 5 signaling in mouse hippocampus

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.03809 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Karim Ibrahim ◽

Caitlyn McLaren ◽

Khaled Abd‐Elrahman ◽

Stephen Ferguson

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Mouse Hippocampus

Selective induction of metabotropic glutamate receptor 1– and metabotropic glutamate receptor 5–dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus

Neuroscience ◽

10.1016/j.neuroscience.2007.09.071 ◽

2008 ◽

Vol 151 (1) ◽

pp. 28-42 ◽

Cited By ~ 22

Author(s):

M. Le Vasseur ◽

I. Ran ◽

J.-C. Lacaille

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Long Term Potentiation ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Term Potentiation ◽

Mouse Hippocampus ◽

Metabotropic Glutamate Receptor 1

The Effects of MPEP, a Selective Metabotropic Glutamate Receptor 5 Antagonist, on Conditioned Taste Aversion in Rats

PsycEXTRA Dataset ◽

10.1037/e413812005-369 ◽

2002 ◽

Author(s):

Todd R. Schachtman ◽

Carla Bills ◽

Rodica Ghinescu ◽

Kevin Murch ◽

Agnes Simonyi

Keyword(s):

Taste Aversion ◽

Glutamate Receptor ◽

Conditioned Taste Aversion ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate

Faculty Opinions recommendation of Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718499023.793498248 ◽

2014 ◽

Author(s):

Roland Seifert

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Transmembrane Domain ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Class C

Faculty Opinions recommendation of Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732704940.793543297 ◽

2018 ◽

Author(s):

Dario Doller

Keyword(s):

G Protein ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Allosteric Modulators ◽

G Protein Coupled Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

X Ray ◽

Metabotropic Glutamate ◽

G Protein Coupled

Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine

Neuroscience Letters ◽

10.1016/j.neulet.2020.135552 ◽

2021 ◽

Vol 743 ◽

pp. 135552

Author(s):

Yingying Niu ◽

Xiaoxu Zeng ◽

Guangcheng Qin ◽

Dunke Zhang ◽

Jiying Zhou ◽

...

Keyword(s):

Chronic Migraine ◽

Glutamate Receptor ◽

Rat Model ◽

Central Sensitization ◽

Metabotropic Glutamate Receptor ◽

Mtor Pathway ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate

Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory

Neuroscience ◽

10.1016/j.neuroscience.2006.06.043 ◽

2006 ◽

Vol 142 (3) ◽

pp. 691-702 ◽

Cited By ~ 67

Author(s):

D. Balschun ◽

W. Zuschratter ◽

W. Wetzel

Keyword(s):

Spatial Memory ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate

Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes

Neuroscience ◽

10.1016/j.neuroscience.2011.12.044 ◽

2012 ◽

Vol 205 ◽

pp. 29-38 ◽

Cited By ~ 26

Author(s):

J.V. Berger ◽

A.O. Dumont ◽

M.C. Focant ◽

M. Vergouts ◽

A. Sternotte ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Metabotropic Glutamate Receptor 3 ◽

Inflammatory Stimuli

Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus

Neuroscience ◽

10.1016/j.neuroscience.2010.06.023 ◽

2010 ◽

Vol 169 (4) ◽

pp. 1567-1574 ◽

Cited By ~ 25

Author(s):

A.H. Iyo ◽

A.M. Feyissa ◽

A. Chandran ◽

M.C. Austin ◽

S. Regunathan ◽

...

Keyword(s):

Protein Expression ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Rat Hippocampus ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate

Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats

Neuropharmacology ◽

10.1016/j.neuropharm.2011.08.028 ◽

2011 ◽

Vol 61 (8) ◽

pp. 1399-1405 ◽

Cited By ~ 28

Author(s):

Manoranjan S. D’Souza ◽

Athina Markou

Keyword(s):

Nucleus Accumbens ◽

Ventral Tegmental Area ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Nucleus Accumbens Shell ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Reinforcing Effects ◽

Ventral Tegmental

Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1107304108 ◽

2011 ◽

Vol 108 (37) ◽

pp. 15219-15224 ◽

Cited By ~ 54

Author(s):

K. Y. Choi ◽

K. Chang ◽

J. M. Pickel ◽

J. D. Badger ◽

K. W. Roche

Keyword(s):

Transgenic Mice ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate