scholarly journals A high protein diet maintains glucose production and enhances gluconeogenesis during exercise induced energy deficit

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Tracey J Smith ◽  
Matthew A Pikosky ◽  
Jean‐Marc Schwartz ◽  
Jennifer Rood ◽  
Carmen Castaneda‐Sceppa ◽  
...  
Keyword(s):  
High Protein Diet ◽  
Glucose Production ◽  
High Protein ◽  
Protein Diet ◽  
Energy Deficit ◽  
Exercise Induced

scholarly journals High protein diet maintains glucose production during exercise-induced energy deficit: a controlled trial

2011 ◽  
Vol 8 (1) ◽  
pp. 26 ◽  
Author(s):  
Tracey J Smith ◽  
Jean-Marc Schwarz ◽  
Scott J Montain ◽  
Jennifer Rood ◽  
Matthew A Pikosky ◽  
...  
Keyword(s):  
Controlled Trial ◽  
High Protein Diet ◽  
Glucose Production ◽  
High Protein ◽  
Protein Diet ◽  
Energy Deficit ◽  
Exercise Induced

scholarly journals A high protein diet preserves nitrogen balance during an exercise induced energy deficit

2006 ◽  
Vol 20 (5) ◽  
Author(s):  
Matthew A Pikosky ◽  
Tracey J Smith ◽  
Ann Grediagin ◽  
Christina Caruso ◽  
Holly L McClung ◽  
...  
Keyword(s):  
Nitrogen Balance ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Energy Deficit ◽  
Exercise Induced

A High Protein Diet Exacerbates the Adverse Effects of an Energy Deficit on Mood State

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S225
Author(s):  
Tracey J. Smith ◽  
Harris R. Lieberman ◽  
J. Phillip Karl ◽  
Susan McGraw ◽  
Matthew A. Pikosky ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Mood State ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Energy Deficit

scholarly journals Gluconeogenesis and protein-induced satiety

2011 ◽  
Vol 107 (4) ◽  
pp. 595-600 ◽  
Author(s):  
Margriet A. B. Veldhorst ◽  
Klaas R. Westerterp ◽  
Margriet S. Westerterp-Plantenga
Keyword(s):  
Human Subjects ◽  
Area Under The Curve ◽  
High Protein Diet ◽  
Glucose Production ◽  
Endogenous Glucose Production ◽  
High Protein ◽  
Protein Diet ◽  
Healthy Human ◽  
Glucose Homoeostasis ◽  
Normal Protein Diet

Increased gluconeogenesis (GNG) has been suggested to contribute to protein-induced satiety via modulation of glucose homoeostasis. The objective was to determine GNG and appetite in healthy human subjects after a high-proteinv.a normal-protein diet and to assess whether GNG contributes to protein-induced satiety. A total of twenty-two healthy subjects (ten men and twelve women: age 23 (sem1) years, BMI 22·1 (sem0·5) kg/m2) received an isoenergetic high-protein (30/0/70 % of energy from protein/carbohydrate/fat) or normal-protein diet (12/55/33 % of energy from protein/carbohydrate/fat) for 1·5 d in a randomised cross-over design. Appetite ratings were measured using visual analogue scales (VAS); endogenous glucose production and GNG were measured via infusion of [6,6-2H2]glucose and ingestion of2H2O. Moreover, fasting glucose and β-hydroxybutyrate concentrations were measured. Glycogen stores were lowered at the start with a glycogen-lowering exercise test. During the high-protein compared with the normal-protein diet, GNG was increased and appetite was suppressed (GNG: 148 (sem7)v.133 (sem6) g/24 h,P < 0·05; and 24 h area under the curve for hunger: 694 (sem46)v.1055 (sem52) mmVAS × 24 h,P < 0·001; fullness: 806 (sem59)v.668 (sem64) mm VAS × 24 h,P < 0·05; desire to eat: 762 (sem48)v.1004 (sem66) mm VAS × 24 h,P < 0·001). There was no correlation between appetite ratings and GNG. Glucose concentration was lower (4·09 (sem0·10)v.4·89 (sem0·06) mmol/l,P < 0·001) and β-hydroxybutyrate concentration was higher (1349 (sem139)v.234 (sem25) μmol/l,P < 0·001) after the high-protein compared with the normal-protein diet. In conclusion, after a high-protein diet, GNG was increased and appetite was lower compared with a normal-protein diet; however, these were unrelated to each other. An increased concentration of β-hydroxybutyrate may have contributed to appetite suppression on the high-protein diet.

scholarly journals A high protein diet upregulates whole‐body protein turnover during energy deficit

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Lee M. Margolis ◽  
Jay J. Cao ◽  
Edward R. Sauter ◽  
Leah D. Whigham ◽  
James P. McClung ◽  
...  
Keyword(s):  
Protein Turnover ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Energy Deficit ◽  
Whole Body ◽  
Body Protein

scholarly journals A high-protein diet increases faecal IgA concentrations in baby pigs

2008 ◽  
Vol 67 (OCE5) ◽  
Author(s):  
F. Vitari ◽  
A. Morise ◽  
M. Formal ◽  
C. Garcia ◽  
K. Mace ◽  
...  
Keyword(s):  
High Protein Diet ◽  
High Protein ◽  
Protein Diet

scholarly journals Measurement of the Intestinal pH in Mice under Various Conditions Reveals Alkalization Induced by Antibiotics

Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 180
Author(s):  
Kouki Shimizu ◽  
Issei Seiki ◽  
Yoshiyuki Goto ◽  
Takeshi Murata
Keyword(s):  
Antibiotic Treatment ◽  
High Protein Diet ◽  
Intestinal Bacteria ◽  
High Protein ◽  
Protein Diet ◽  
Germ Free ◽  
Treatment Regimens ◽  
Ph Values ◽  
Specific Pathogen ◽  
The Stability

The intestinal pH can greatly influence the stability and absorption of oral drugs. Therefore, knowledge of intestinal pH is necessary to understand the conditions for drug delivery. This has previously been measured in humans and rats. However, information on intestinal pH in mice is insufficient despite these animals being used often in preclinical testing. In this study, 72 female ICR mice housed in SPF (specific pathogen-free) conditions were separated into nine groups to determine the intestinal pH under conditions that might cause pH fluctuations, including high-protein diet, ageing, proton pump inhibitor (PPI) treatment, several antibiotic treatment regimens and germ-free mice. pH was measured in samples collected from the ileum, cecum and colon, and compared to control animals. An electrode, 3 mm in diameter, enabled accurate pH measurements with a small amount of gastrointestinal content. Consequently, the pH values in the cecum and colon were increased by high-protein diet, and the pH in the ileum was decreased by PPI. Drastic alkalization was induced by antibiotics, especially in the cecum and colon. The alkalized pH values in germ-free mice suggested that the reduction in the intestinal bacteria caused by antibiotics led to alkalization. Alkalization of the intestinal pH caused by antibiotic treatment was verified in mice. We need further investigations in clinical settings to check whether the same phenomena occur in patients.

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