scholarly journals Sphingolipid Ratios in Marine Mammal Skeletal Muscle Cell Membranes:Protection from Oxidative Stress?

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Kathryn Young ◽  
Stephen Trumble
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Muscle Cell ◽  
Marine Mammal ◽  
Skeletal Muscle Cell

Blueberry fruit polyphenolics suppress oxidative stress-induced skeletal muscle cell damagein vitro

2010 ◽  
Vol 54 (3) ◽  
pp. 353-363 ◽  
Author(s):  
Roger D. Hurst ◽  
Robyn W. Wells ◽  
Suzanne M. Hurst ◽  
Tony K. McGhie ◽  
Janine M. Cooney ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Muscle Cell ◽  
Skeletal Muscle Cell

Skeletal Muscle Cell Oxidative Stress as a Possible Therapeutic Target in a Denervation-Induced Experimental Sarcopenic Model

Spine ◽  
2019 ◽  
Vol 44 (8) ◽  
pp. E446-E455 ◽  
Author(s):  
Hideyuki Kinoshita ◽  
Sumihisa Orita ◽  
Kazuhide Inage ◽  
Kazuyo Yamauchi ◽  
Koki Abe ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Muscle Cell ◽  
Therapeutic Target ◽  
Skeletal Muscle Cell

scholarly journals Amla Enhances Mitochondrial Spare Respiratory Capacity by Increasing Mitochondrial Biogenesis and Antioxidant Systems in a Murine Skeletal Muscle Cell Line

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Hirotaka Yamamoto ◽  
Katsutaro Morino ◽  
Lemecha Mengistu ◽  
Taishi Ishibashi ◽  
Kohei Kiriyama ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Muscle Cell ◽  
Mitochondrial Biogenesis ◽  
Mitochondrial Function ◽  
Skeletal Muscle Cell ◽  
Antioxidant Systems ◽  
Respiratory Capacity ◽  
Age Related ◽  
Murine Skeletal Muscle

Amla is one of the most important plants in Indian traditional medicine and has been shown to improve various age-related disorders while decreasing oxidative stress. Mitochondrial dysfunction is a proposed cause of aging through elevated oxidative stress. In this study, we investigated the effects of Amla on mitochondrial function in C2C12 myotubes, a murine skeletal muscle cell model with abundant mitochondria. Based on cell flux analysis, treatment with an extract of Amla fruit enhanced mitochondrial spare respiratory capacity, which enables cells to overcome various stresses. To further explore the mechanisms underlying these effects on mitochondrial function, we analyzed mitochondrial biogenesis and antioxidant systems, both proposed regulators of mitochondrial spare respiratory capacity. We found that Amla treatment stimulated both systems accompanied by AMPK and Nrf2 activation. Furthermore, we found that Amla treatment exhibited cytoprotective effects and lowered reactive oxygen species (ROS) levels in cells subjected to t-BHP-induced oxidative stress. These effects were accompanied by increased oxygen consumption, suggesting that Amla protected cells against oxidative stress by using enhanced spare respiratory capacity to produce more energy. Thus we identified protective effects of Amla, involving activation of mitochondrial function, which potentially explain its various effects on age-related disorders.

scholarly journals Skeletal muscle cell oxidative stress as a possible therapeutic target in a sarcopenia

Bone Reports ◽  
2021 ◽  
Vol 14 ◽  
pp. 100954
Author(s):  
Hideyuki Kinoshita ◽  
Sumihisa Orita ◽  
Kazuhide Inage ◽  
Seiji Ohtori
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Muscle Cell ◽  
Therapeutic Target ◽  
Skeletal Muscle Cell

Skeletal muscle cell transplantation: models and methods

2019 ◽  
Vol 41 (4) ◽  
pp. 297-311 ◽  
Author(s):  
Amber L. Mueller ◽  
Robert J. Bloch
Keyword(s):  
Skeletal Muscle ◽  
Cell Transplantation ◽  
Muscle Cell ◽  
Skeletal Muscle Cell

THE MYOGRAM OF THE ISOLATED SKELETAL MUSCLE CELL

Science ◽  
1930 ◽  
Vol 72 (1853) ◽  
pp. 17-18 ◽  
Author(s):  
D. E. S. Brown ◽  
F. J. M. Sichel
Keyword(s):  
Skeletal Muscle ◽  
Muscle Cell ◽  
Skeletal Muscle Cell
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