scholarly journals Chronic hypoxia (10% O 2 ) alters cardiovascular regulation and gene expression in Snapping turtle embryos ( Chelydra serpentina )

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
John Eme ◽  
Turk Rhen ◽  
Kevin B Tate ◽  
Kathryn Gruchalla ◽  
Zachary F Kohl ◽  
...  
Keyword(s):  
Gene Expression ◽  
Chronic Hypoxia ◽  
Cardiovascular Regulation ◽  
Chelydra Serpentina ◽  
Snapping Turtle

scholarly journals Phenotypic plasticity in the common snapping turtle (Chelydra serpentina): long-term physiological effects of chronic hypoxia during embryonic development

2016 ◽  
Vol 310 (2) ◽  
pp. R176-R184 ◽  
Author(s):  
Oliver H. Wearing ◽  
John Eme ◽  
Turk Rhen ◽  
Dane A. Crossley
Keyword(s):  
Chronic Hypoxia ◽  
Common Garden ◽  
Physiological Effects ◽  
Chelydra Serpentina ◽  
Long Term Effects ◽  
Snapping Turtle ◽  
Snapping Turtles ◽  
The Common ◽  
Hypoxic Incubation

Studies of embryonic and hatchling reptiles have revealed marked plasticity in morphology, metabolism, and cardiovascular function following chronic hypoxic incubation. However, the long-term effects of chronic hypoxia have not yet been investigated in these animals. The aim of this study was to determine growth and postprandial O2 consumption (V̇o2), heart rate ( fH), and mean arterial pressure ( Pm, in kPa) of common snapping turtles ( Chelydra serpentina) that were incubated as embryos in chronic hypoxia (10% O2, H10) or normoxia (21% O2, N21). We hypothesized that hypoxic development would modify posthatching body mass, metabolic rate, and cardiovascular physiology in juvenile snapping turtles. Yearling H10 turtles were significantly smaller than yearling N21 turtles, both of which were raised posthatching in normoxic, common garden conditions. Measurement of postprandial cardiovascular parameters and O2 consumption were conducted in size-matched three-year-old H10 and N21 turtles. Both before and 12 h after feeding, H10 turtles had a significantly lower fH compared with N21 turtles. In addition, V̇o2 was significantly elevated in H10 animals compared with N21 animals 12 h after feeding, and peak postprandial V̇o2 occurred earlier in H10 animals. Pm of three-year-old turtles was not affected by feeding or hypoxic embryonic incubation. Our findings demonstrate that physiological impacts of developmental hypoxia on embryonic reptiles continue into juvenile life.

scholarly journals Chronic Perinatal Hypoxia Delays Cardiac Maturation in a Mouse Model for Cyanotic Congenital Heart Disease

2020 ◽  
Author(s):  
Jennifer Romanowicz ◽  
Zaenab Dhari ◽  
Devon Guerrelli ◽  
Colm Mulvany ◽  
Marissa Reilly ◽  
...  
Keyword(s):  
Gene Expression ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Chronic Hypoxia ◽  
Cardiac Development ◽  
Contractile Function ◽  
Adverse Outcomes ◽  
Perinatal Hypoxia ◽  
Postnatal Environment

AbstractBackgroundCompared to acyanotic congenital heart disease (CHD), cyanotic CHD has an increased risk of lifelong mortality and morbidity. These adverse outcomes may be attributed to delayed cardiomyocyte maturation, since the transition from a hypoxic fetal milieu to oxygen rich postnatal environment is disrupted. We established a rodent model to replicate hypoxic myocardial conditions spanning perinatal development, and tested the hypothesis that chronic hypoxia impairs cardiac development.MethodsMouse dams were housed in hypoxia beginning at embryonic day 16. Pups stayed in hypoxia until postnatal day (P)8 when cardiac development is nearly complete. Global gene expression was quantified at P8 and at P30, after recovering in normoxia. Phenotypic testing included electrocardiogram, echocardiogram, and ex-vivo electrophysiology study.ResultsHypoxic animals were 48% smaller than controls. Gene expression was grossly altered by hypoxia at P8 (1427 genes affected), but normalized after recovery (P30). Electrocardiograms revealed bradycardia and slowed conduction velocity in hypoxic animals at P8, which resolved after recovery (P30). Notable differences that persisted after recovery (P30) included a 65% prolongation in ventricular effective refractory period, sinus node dysfunction, and a 24% reduction in contractile function in animals exposed to hypoxia.ConclusionsWe investigated the impact of chronic hypoxia on the developing heart. Perinatal hypoxia was associated with changes in gene expression and cardiac function. Persistent changes to the electrophysiologic substrate and contractile function warrant further investigation, and may contribute to adverse outcomes observed in the cyanotic CHD population.

scholarly journals New size record for Snapping Turtle (Chelydra serpentina) in southern Quebec, Canada

2019 ◽  
Vol 132 (4) ◽  
pp. 378-381
Author(s):  
Patrick Galois ◽  
Ève-Lyne Grenier ◽  
Martin Ouellet
Keyword(s):  
Population Structure ◽  
Adult Male ◽  
General Condition ◽  
Carapace Length ◽  
Maximum Size ◽  
Chelydra Serpentina ◽  
Snapping Turtle ◽  
Good General Condition ◽  
Turtle Population ◽  
Local Habitat

We report a new size record for a Snapping Turtle (Chelydra serpentina) in Quebec, Canada. We captured an adult male in good general condition in the Rivière du Sud in the southern Montérégie region. Its straight midline carapace length was 43.2 cm (maximum carapace length 45.1 cm), and it weighed 19.8 kg. This record contributes to our understanding of the maximum size of this species at the northeastern part of its range. More intensive effort will be necessary to document the Snapping Turtle population structure in Quebec to allow for sound comparisons with other populations, as well as a better understanding of the effects of elevation, latitude, and local habitat on Snapping Turtle growth and size.

scholarly journals Snapping Turtle—Tortue serpentine—turtle mi’ kjikj (snapping; Chelydra serpentina), added to the herpetofauna of Cape Breton Island, Nova Scotia, Canada

2018 ◽  
Vol 132 (1) ◽  
pp. 4-7
Author(s):  
John Gilhen ◽  
Terry Power
Keyword(s):  
Nova Scotia ◽  
Natural History ◽  
Natural Resources ◽  
Chelydra Serpentina ◽  
Cape Breton Island ◽  
Snapping Turtle ◽  
The Public ◽  
Cape Breton

Snapping Turtle (Chelydra serpentina) is native to mainland Nova Scotia, but its status on Cape Breton Island has been uncertain. Although it was recorded from Cape Breton Island as early as 1953, until 1984, it was known from only three widely scattered locations. Since that time, additional reports received from the public by Nova Scotia Department of Natural Resources and the Nova Scotia Museum of Natural History suggest that the species is native to Cape Breton Island. Thus, we are adding Snapping Turtle to the native herpetofauna of Cape Breton Island, Nova Scotia.

scholarly journals Effects of chronic hypoxia on renal renin gene expression in rats

2000 ◽  
Vol 15 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Frank Schweda ◽  
Friedrich C. Blumberg ◽  
Annette Schweda ◽  
Martin Kammerl ◽  
Stephan R. Holmer ◽  
...  
Keyword(s):  
Gene Expression ◽  
Chronic Hypoxia ◽  
Renin Gene

Fine Structure of the Corpus Luteum of the Snapping Turtle, Chelydra serpentina

Copeia ◽  
1978 ◽  
Vol 1978 (4) ◽  
pp. 622 ◽  
Author(s):  
Rodney V. Cyrus ◽  
I. Y. Mahmoud ◽  
John Klicka
Keyword(s):  
Fine Structure ◽  
Corpus Luteum ◽  
Chelydra Serpentina ◽  
Snapping Turtle

Conservation Genetics of the Common Snapping Turtle (Chelydra serpentina)

1996 ◽  
Vol 10 (2) ◽  
pp. 397-405 ◽  
Author(s):  
Christopher A. Phillips ◽  
Walter W. Dimmick ◽  
John L. Carr
Keyword(s):  
Conservation Genetics ◽  
Chelydra Serpentina ◽  
Snapping Turtle ◽  
The Common
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