INVESTIGATING THE IMPACT OF PRE-AMPUTATION OCCUPATIONAL STATUS ON THE REHABILITATION AND QUALITY OF LIFE OF UPPER LIMB AMPUTEES EXPERIENCING PHANTOM LIMB PAIN

2006 ◽  
Vol 85 (3) ◽  
pp. 249
Author(s):  
David Berbrayer
Keyword(s):  
Quality Of Life ◽  
Upper Limb ◽  
Occupational Status ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain ◽  
The Impact

Factors related to phantom limb pain and its effect on quality of life

2021 ◽  
pp. 1-5
Author(s):  
Cemile S. Polat ◽  
Hatice E. Konak ◽  
Elif U. Altas ◽  
Meltem G. Akıncı ◽  
Sule S. Onat
Keyword(s):  
Quality Of Life ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain

scholarly journals Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e021039 ◽  
Author(s):  
Eva Lendaro ◽  
Liselotte Hermansson ◽  
Helena Burger ◽  
Corry K Van der Sluis ◽  
Brian E McGuire ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Controlled Clinical Trial ◽  
Motor Execution ◽  
Limb Pain ◽  
Double Blind ◽  
Randomised Controlled Clinical Trial ◽  
Randomised Controlled

IntroductionPhantom limb pain (PLP) is a chronic condition that can greatly diminish quality of life. Control over the phantom limb and exercise of such control have been hypothesised to reverse maladaptive brain changes correlated to PLP. Preliminary investigations have shown that decoding motor volition using myoelectric pattern recognition, while providing real-time feedback via virtual and augmented reality (VR-AR), facilitates phantom motor execution (PME) and reduces PLP. Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysisSixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. Subjects allocated to either treatment receive 15 interventions and are exposed to the same VR-AR environments using the same device. The only difference between interventions is whether phantom movements are actually performed (PME) or just imagined (PMI). Complete evaluations are conducted at baseline and at intervention completion, as well as 1, 3 and 6 months later using an intention-to-treat (ITT) approach. Changes in PLP measured using the Pain Rating Index between the first and last session are the primary measure of efficacy. Secondary outcomes include: frequency, duration, quality of pain, intrusion of pain in activities of daily living and sleep, disability associated to pain, pain self-efficacy, frequency of depressed mood, presence of catastrophising thinking, health-related quality of life and clinically significant change as patient’s own impression. Follow-up interviews are conducted up to 6 months after the treatment.Ethics and disseminationThe study is performed in agreement with the Declaration of Helsinki and under approval by the governing ethical committees of each participating clinic. The results will be published according to the Consolidated Standards of Reporting Trials guidelines in a peer-reviewed journal.Trial registration numberNCT03112928; Pre-results.

scholarly journals Anxiety, depression and quality of life in individuals with phantom limb pain

2015 ◽  
Vol 23 (2) ◽  
pp. 107-110 ◽  
Author(s):  
Mariana Theozzo Padovani ◽  
Marielza Regina Ismael Martins ◽  
Alexandre Venâncio ◽  
José Eduardo Nogueira Forni
Keyword(s):  
Quality Of Life ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain ◽  
Anxiety Depression

scholarly journals Brain and spinal stimulation therapies for phantom limb pain: a systematic review

2018 ◽  
Vol 22 (62) ◽  
pp. 1-94 ◽  
Author(s):  
Mark Corbett ◽  
Emily South ◽  
Melissa Harden ◽  
Sam Eldabe ◽  
Erlick Pereira ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Randomised Trial ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain ◽  
Short Term ◽  
Comparative Group ◽  
Epidemiology Studies

Background Although many treatments exist for phantom limb pain (PLP), the evidence supporting them is limited and there are no guidelines for PLP management. Brain and spinal cord neurostimulation therapies are targeted at patients with chronic PLP but have yet to be systematically reviewed. Objective To determine which types of brain and spinal stimulation therapy appear to be the best for treating chronic PLP. Design Systematic reviews of effectiveness and epidemiology studies, and a survey of NHS practice. Population All patients with PLP. Interventions Invasive interventions – deep brain stimulation (DBS), motor cortex stimulation (MCS), spinal cord stimulation (SCS) and dorsal root ganglion (DRG) stimulation. Non-invasive interventions – repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). Main outcome measures Phantom limb pain and quality of life. Data sources Twelve databases (including MEDLINE and EMBASE) and clinical trial registries were searched in May 2017, with no date limits applied. Review methods Two reviewers screened titles and abstracts and full texts. Data extraction and quality assessments were undertaken by one reviewer and checked by another. A questionnaire was distributed to clinicians via established e-mail lists of two relevant clinical societies. All results were presented narratively with accompanying tables. Results Seven randomised controlled trials (RCTs), 30 non-comparative group studies, 18 case reports and 21 epidemiology studies were included. Results from a good-quality RCT suggested short-term benefits of rTMS in reducing PLP, but not in reducing anxiety or depression. Small randomised trials of tDCS suggested the possibility of modest, short-term reductions in PLP. No RCTs of invasive therapies were identified. Results from small, non-comparative group studies suggested that, although many patients benefited from short-term pain reduction, far fewer maintained their benefits. Most studies had important methodological or reporting limitations and few studies reported quality-of-life data. The evidence on prognostic factors for the development of chronic PLP from the longitudinal studies also had important limitations. The results from these studies suggested that pre-amputation pain and early PLP intensity are good predictors of chronic PLP. Results from the cross-sectional studies suggested that the proportion of patients with severe chronic PLP is between around 30% and 40% of the chronic PLP population, and that around one-quarter of chronic PLP patients find their PLP to be either moderately or severely limiting or bothersome. There were 37 responses to the questionnaire distributed to clinicians. SCS and DRG stimulation are frequently used in the NHS but the prevalence of use of DBS and MCS was low. Most responders considered SCS and DRG stimulation to be at least sometimes effective. Neurosurgeons had mixed views on DBS, but most considered MCS to rarely be effective. Most clinicians thought that a randomised trial design could be successfully used to study neurostimulation therapies. Limitation There was a lack of robust research studies. Conclusions Currently available studies of the efficacy, effectiveness and safety of neurostimulation treatments do not provide robust, reliable results. Therefore, it is uncertain which treatments are best for chronic PLP. Future work Randomised crossover trials, randomised N-of-1 trials and prospective registry trials are viable study designs for future research. Study registration The study is registered as PROSPERO CRD42017065387. Funding The National Institute for Health Research Health Technology Assessment programme.

scholarly journals Veidrodžio terapijos reikšmė motorinei bei sensorinei funkcijai, skausminiam sindromui bei asocijuotos galvos smegenų žievės reorganizacijai po persirgto insulto

2017 ◽  
Vol 26 (6) ◽  
pp. 189-194
Author(s):  
Monika Žilionytė ◽  
Jurgita Savickaitė ◽  
Andrius Kederys ◽  
Lina Varžaitytė
Keyword(s):  
Visual Feedback ◽  
Upper Limb ◽  
Mirror Neurons ◽  
Recovery Of Function ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Mirror Therapy ◽  
Limb Pain ◽  
Mirror Visual Feedback ◽  
Mirror Movement

Tyrimo tikslas – apžvelgti patikimais įrodymais pagrįstą literatūrą apie veidrodinės terapijos (VT) efektyvumą pacientams, persirgusiems galvos smegenų insultu. Tyrimo medžiaga ir metodai. Atliekant sisteminę apžvalgą, mokslinių straipsnių paieška vykdyta duomenų bazėse: PubMed, BioMedCentral, Tylor&Francis, CohraneLibrary, ScienceDirect. Mokslinių straipsnių paieška atlikta pagal kiekvienai duomenų bazei pritaikytą specialią paieškos strategiją. Paieškai buvo panaudoti šie raktažodžiai: „mirror therapy“, „rehabilitation“, „stroke“, „upper limb“, „recovery of function“, „mirror movement“, „phantom limb pain „, „mirror visual feedback“, „mirror neurons system“. Į sisteminę apžvalgą įtraukti anglų kalba 2008–2016 metais publikuoti atsitiktinių imčių kontroliuojami arba kontroliuojami prieš ir po tyrimai, kuriuose buvo vertinama VT įtaka paralyžiuotos galūnės motorinei ir sensorinei funkcijai, skausmo intensyvumui bei asocijuotos galvos smegenų žievės reorganizacijai. Tyrimo rezultatai. Į sisteminę apžvalgą įtraukta 11 tyrimų. Tyrimuose buvo suformuotos dvi grupės: tiriamųjų, kuriems buvo taikyta standartinė bei VT, ir kontrolinė grupė, kuriai buvo taikoma tik standartinė terapija. Daugelyje tyrimų VT taikyta vieną mėnesį. Rezultatai buvo vertinami prieš taikytą terapiją ir po jos. Apžvelgus visus šiuos 11 straipsnių stebime, kad tose tiriamųjų grupėse, kuriose naudojama VT, ženkliai pagerėja pacientų paralyžiuotos galūnės motorinė funkcija, padidėja vikrumas, sumažėja skausmas. Išvados. VT didina smegenų aktyvumą ipsilateralinėje motorinėje žievėje, somatosensorinėje zonoje, skatina asocijuotos žievės reorganizaciją, taip pat ji padeda pasiekti geresnių rezultatų pacientams, patyrusiems nedominuojančio pusrutulio insultą, sumažina persirgus insultu atsiradusį skausmą bei padidina po insulto sumažėjusį galūnių vikrumą. VT yra veiksminga ne tik gydant ūmiu ir poūmiu insultu, tačiau ir lėtiniu galvos smegenų insultu sergančius pacientus.

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