Fluid Dynamic Characterization of Operating Conditions for Continuous Flow Blood Pumps

ASAIO Journal ◽  
1999 ◽  
Vol 45 (5) ◽  
pp. 442-449 ◽  
Author(s):  
ZHONGJUN J. WU ◽  
JAMES F. ANTAKI ◽  
GREG W. BURGREEN ◽  
KENNETH C. BUTLER ◽  
DOUGLAS C. THOMAS ◽  
...  
2019 ◽  
Vol 144 ◽  
pp. 247-257 ◽  
Author(s):  
Haiyun Ma ◽  
Nan Jin ◽  
Peng Zhang ◽  
Yufei Zhou ◽  
Yuchao Zhao ◽  
...  

AIChE Journal ◽  
2017 ◽  
Vol 63 (9) ◽  
pp. 4177-4187 ◽  
Author(s):  
Douglas T. J. Marsh ◽  
Gary J. Lye ◽  
Martina Micheletti ◽  
Akinlolu O. O. Odeleye ◽  
Andrea Ducci ◽  
...  

2021 ◽  
Vol 1977 (1) ◽  
pp. 012007
Author(s):  
Paolo Candeloro ◽  
Ranieri Emanuele Nargi ◽  
Edoardo Grande ◽  
Daniele Ragni ◽  
Tiziano Pagliaroli

2014 ◽  
Vol 58 (04) ◽  
pp. 216-224 ◽  
Author(s):  
Esben Orlowitz ◽  
Anders Brandt

The dynamic characteristics of ship structures are becoming more important as the flexibility of modern ships increases, for example, to predict reliable design life. This requires an accurate dynamic model of the structure, which, because of complex vibration environment and complex boundary conditions, can only be validated by measurements. In the present paper the use of operational modal analysis (OMA) for dynamic characterization of a ship structure based on experimental data, from a full-scale measurement of a 210-m long Ro-Lo ship during sea trial, is presented. The measurements contain three different data sets obtained under different operating conditions of the ship: 10 knots cruising speed, 18 knots cruising speed, and at anchor. Natural frequencies, modal damping ratios, and mode shapes have been successfully estimated for the first 10 global modes. Damping ratios for the current ship were found within the range 0.9%–1.9% and natural frequencies were found to range from 0.8 to 4.1 Hz for the first 10 global modes of the ship at design speed (18 knots). The three different operating conditions showed, in addition, a speed dependency of the natural frequencies and damping ratios. The natural frequencies were found to be lower for the 18-knots condition compared with the two other conditions, most significantly for the vertical bending modes. Also, for the vertical bending modes, the damping ratios increased by 28%–288% when the speed increased from 10 to 18 knots. Other modes were not found to have the same strong speed dependency.


2017 ◽  
Vol 10 (5) ◽  
pp. 2275-2287
Author(s):  
Stefania Falfari ◽  
Gian Marco Bianchi ◽  
Giacomo Micci ◽  
Augusto Della Torre ◽  
Gianluca Montenegro ◽  
...  

Author(s):  
Christopher Blum ◽  
Sascha Groß-Hardt ◽  
Ulrich Steinseifer ◽  
Michael Neidlin

Abstract Purpose Thrombosis ranks among the major complications in blood-carrying medical devices and a better understanding to influence the design related contribution to thrombosis is desirable. Over the past years many computational models of thrombosis have been developed. However, numerically cheap models able to predict localized thrombus risk in complex geometries are still lacking. The aim of the study was to develop and test a computationally efficient model for thrombus risk prediction in rotary blood pumps. Methods We used a two-stage approach to calculate thrombus risk. The first stage involves the computation of velocity and pressure fields by computational fluid dynamic simulations. At the second stage, platelet activation by mechanical and chemical stimuli was determined through species transport with an Eulerian approach. The model was compared with existing clinical data on thrombus deposition within the HeartMate II. Furthermore, an operating point and model parameter sensitivity analysis was performed. Results Our model shows good correlation (R2 > 0.93) with clinical data and identifies the bearing and outlet stator region of the HeartMate II as the location most prone to thrombus formation. The calculation of thrombus risk requires an additional 10–20 core hours of computation time. Conclusion The concentration of activated platelets can be used as a surrogate and computationally low-cost marker to determine potential risk regions of thrombus deposition in a blood pump. Relative comparisons of thrombus risk are possible even considering the intrinsic uncertainty in model parameters and operating conditions.


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