Role of Impairment of Blood Supply of the Femoral Head in the Pathogenesis of Idiopathic Osteonecrosis

1992 ◽  
Vol &NA; (277) ◽  
pp. 22???30 ◽  
Author(s):  
TAKASHI ATSUMI ◽  
YOSHIKATSU KUROKI
Keyword(s):  
Femoral Head ◽  
Blood Supply

scholarly journals ROLE OF PANCHTIKTA KSHIRA BASTI IN MANAGEMENT OF AVASCULAR NECROSIS: A CASE STUDY

2021 ◽  
Vol 12 (01) ◽  
Author(s):  
Dr Pankaj Sharma ◽  
Dr Pankaj Sharma
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Blood Supply ◽  
Musculoskeletal Disorder ◽  
Bone Cells ◽  
Modern Medicine ◽  
Surgical Operation ◽  
Bone Necrosis

Avascular necrosis additionally referred to as osteo-necrosis or Ischemic bone necrosis is a condition that occurs when there is a loss of blood supply of bone. An interruption in the blood supply causes bone cells to die. AVN of femoral head is that the commonest sort of necrosis affecting the bone. In Ayurveda, It correlated with asthimajjagata vaat (musculoskeletal disorder). An effort has been made within the present study to gauge the efficacy of panchtikta kshir basti in conservative management of femoral head necrosis of the bone. In Modern medicine, no any unique remedy as opposed to surgical operation is available.

scholarly journals Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head

2017 ◽  
Vol 46 (6) ◽  
pp. 2141-2148 ◽  
Author(s):  
Qiankun Zhang ◽  
Jin L v ◽  
Lie Jin
Keyword(s):  
Endothelial Cell ◽  
Femoral Head ◽  
Blood Supply ◽  
Fat Embolism ◽  
Aetiological Factor ◽  
Traditional Theory ◽  
Coagulation Disorders ◽  
Cell Dysfunction ◽  
Common Causes

The two major theories of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) are apoptosis and ischaemia. The traditional theory implicates ischaemia as the main aetiological factor because the final common pathway of ONFH is interruption of blood supply to the bone. The most common causes of interruption of blood supply include fat embolism and coagulation disorders. GCs can directly or indirectly lead to coagulation disorders, producing a hypercoagulable state, followed by poor blood flow, ischaemia, and eventually ONFH. This review summarizes the existing knowledge on coagulation disorders in the context of GC-induced ONFH, including hypofibrinolysis and thrombophilia, endothelial cell dysfunction and damage, endothelial cell apoptosis, lipid metabolism, platelet activation, and the effect of anticoagulant treatment.

scholarly journals Serotonin and the renal blood supply: Role of prostaglandins and the 5HT-2 receptor

1986 ◽  
Vol 30 (3) ◽  
pp. 304-310 ◽  
Author(s):  
Joseph L. Blackshear ◽  
Cesare Orlandi ◽  
Norman K. Hollenberg
Keyword(s):  
Blood Supply

THE ETIOLOGY OF KIENBÖCK'S DISEASE — A HISTOPATHOLOGICAL STUDY

Hand Surgery ◽  
1998 ◽  
Vol 03 (01) ◽  
pp. 63-69 ◽  
Author(s):  
H.-G. Simank ◽  
M. Schiltenwolf ◽  
W. Krempien
Keyword(s):  
Femoral Head ◽  
Blood Supply ◽  
Primary Lesion ◽  
Histopathological Study ◽  
Arterial Blood Supply ◽  
Lunate Bone ◽  
Kienböck’S Disease ◽  
Kienböck's Disease ◽  
Arterial Blood ◽  
Kienbock’S Disease

The etiology of the necrosis of the lunate bone is still unclear. In today's theories, the necrosis is explained by impairment of the arterial bone circulation or fracture following mechanical overloading. In this study, six specimen in different stages of the disease were investigated histologically. In all the specimens, focal necrosis was detected, but also signs of regeneration, i.e. immature bone formation. No signs of fracture were seen in all stages of the disease. These findings are not compatible with sudden interruption of arterial blood supply or fracture of the lunate bone as a primary lesion. Comparable histological patterns are known in the necrosis of the femoral head. The etiological model of necrosis of the femoral head is well investigated and postulates primary marrow hypertension, induced by impairment of the venous drainage. Our results are contradictory to the etiological theories of fracture or breakdown of the arterial blood supply as a primary lesion in Kienböck's disease, and support the assumption that the model of intraosseous hypertension is transferable to the necrosis of the lunate bone.

scholarly journals Mechanisms Involved in Apice Closure of Pulpless Teeth – Literature Review

2021 ◽  
Vol 15 (1) ◽  
pp. 127-136
Author(s):  
Alexandrino Pereira dos Santos Neto ◽  
Sandra Maria Alves Sayão Maia ◽  
Jair Carneiro Leão ◽  
Iliana Lins Quidute ◽  
Carolina dos Santos Guimarães ◽  
...  
Keyword(s):  
Stem Cells ◽  
Literature Review ◽  
Blood Supply ◽  
Root Formation ◽  
Adequate Blood Supply ◽  
Revascularization Therapy ◽  
Oral Stem Cells ◽  
Pulp Revascularization ◽  
Professional Intervention

Background: Unfinished root formation has always offered challenges in endodontics due to technical difficulties and weakened teeth resistance during the lifetime of an individual. Pulp revascularization therapy appeared as a solution for apical closure and root maturation. The existence of oral stem cells involved in the process associated with traditional resident cells requires adequate blood supply given by induced controlled injury deliberately accomplished into the periapical zone. Objective: The aim of this work was to research, through literature review, the main mechanisms involved in the process of apical closure through the technique of pulp revascularization. Conclusion: Apice closure in pulpless teeth seems to happen as a result of professional intervention and biological activity. The success rate depends on the role of traditional local immune cells and stem cells associated with adequate blood supply to finish root formation.

scholarly journals Role of Ayurveda in the conservative management of avascular necrosis of the femoral head: A case study

2016 ◽  
Vol 35 (3) ◽  
pp. 173
Author(s):  
Ashutosh Chaturvedi ◽  
MAshvini Kumar ◽  
BA Lohith ◽  
BS Praveen ◽  
C Swathi
Keyword(s):  
Femoral Head ◽  
Avascular Necrosis ◽  
Conservative Management
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