Epidemiology of Major Amputations in a Burn Unit: A High Morbidity and High Mortality Injury

2001 ◽  
Vol 22 ◽  
pp. S113
Author(s):  
J. L. Hunt ◽  
G. F. Purdue
Keyword(s):  
High Mortality ◽  
High Morbidity ◽  
Burn Unit

scholarly journals A naturally acquired infection of laboratory mice with Klebsiella Capsule type 6

1976 ◽  
Vol 10 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Helen D. Schneemilch
Keyword(s):  
Klebsiella Pneumoniae ◽  
Nude Mice ◽  
High Mortality ◽  
Laboratory Animals ◽  
High Morbidity ◽  
Laboratory Mice ◽  
Capsule Type ◽  
Experimental Inoculation

An epizootic causing high morbidity and high mortality in Swiss White and Nude mice over a period of 3 weeks was caused by Klebsiella pneumoniae Capsule type 6, which is considered to be nonpathogenic for mice. Experimental inoculation of this organism into laboratory animals caused death within 36 hours, further substantiating its virulence.

scholarly journals How to initiate eHealth in congenital heart disease patients?

2020 ◽  
Vol 1 (1) ◽  
pp. 83-86
Author(s):  
Mark J Schuuring ◽  
Dirkjan Kauw
Keyword(s):  
Health Care ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Mortality Rate ◽  
High Mortality ◽  
Congenital Heart ◽  
High Morbidity ◽  
Vulnerable Patients ◽  
Number Of Patients

Abstract Patients with congenital heart disease (CHD) are a vulnerable subgroup of cardiac patients. These patients have a high morbidity and high mortality rate. As the number of patients with CHD keeps growing, while also getting older, new tools for the care and follow-up of these vulnerable patients are warranted. eHealth has an enormous potential to revolutionize health care, and particularly for CHD patients, by expanding care beyond hospital walls and even moving some of the provided care to the comfort of home. As new eHealth tools continue to grow in number, such as invasive eHealth tools, health care delivered through eHealth continues to evolve. This teaching series summarizes current insights and discusses challenges yet to be overcome. Importantly, none of them are insurmountable. This all lays ground for a promising future for eHealth in the care of patients with CHD.

scholarly journals Electrical injuries in adult patients – 3 years overview

2021 ◽  
Vol 16 (3) ◽  
pp. 387-393
Author(s):  
Andreea GROSU-BULARDA ◽  
◽  
Mihaela-Cristina ANDREI ◽  
Adrian FRUNZĂ ◽  
Florin-Vlad HODEA ◽  
...  
Keyword(s):  
Multidisciplinary Treatment ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Clear Understanding ◽  
Electric Injuries ◽  
Burn Unit ◽  
Injured Patients ◽  
Optimal Therapeutic Strategy ◽  
Electrical Injuries

Electrocutions are a particular type of trauma, usually affecting young active people, leading to high morbidity and mortality rates in extensive injured patients. Those patients require complex, multidisciplinary treatment in specialized burn centers. We conducted a three-year retrospective study in the Burn Unit of the Clinical Emergency Hospital Bucharest, Romania, aiming to identify different factors that characterize electrical injuries, with the goal to improve our clinical practice, in order to decrease overall complications, the morbidity and mortality rates and obtain an optimal functional prognosis for those severely injured patients. Patient-related and injury-related parameters were analyzed, and particularities observed in our burn unit were noted. A clear understanding of the physiopathology of those injuries and their complications is essential for providing an optimal therapeutic strategy. Rapid initiation of systemic supportive measures, accurate diagnostic and an adequate surgical treatment, correctly conducted, are essential for improving the vital and functional prognostic of patients who suffer electric injuries.

scholarly journals Austrian Syndrome: a report of an exceptionally rare and deadly syndrome

2020 ◽  
Vol 53 (4) ◽  
pp. 468-471
Author(s):  
Gustavo Nobre de Jesus ◽  
Tânia Carvalho ◽  
Alexandre Caldeira ◽  
Susana M. Fernandes
Keyword(s):  
Respiratory Failure ◽  
High Mortality ◽  
Cardiac Involvement ◽  
Medical Condition ◽  
Pneumococcal Infection ◽  
Neurological Complications ◽  
High Morbidity ◽  
Transesophageal Echocardiogram ◽  
Pneumococcal Bacteremia ◽  
Very High

Austrian Syndrome is the rare combination of a triad of endocarditis, meningitis, and pneumonia in the context of pneumococcal infection. Due to the involvement of several anatomical sites, the Austrian syndrome has a high mortality. Importantly, endocarditis is usually not considered during pneumococcal infection. We present a case of Austrian syndrome in a previously healthy 67-year-old woman. She featured with mental state alteration, respiratory failure, and shock, and was diagnosed with ceftriaxone-sensitive pneumococcal bacteremia, meningitis, and pneumonia. A transesophageal echocardiogram revealed vegetation of the mitral valve. Despite an improvement in her medical condition, she remained in a coma and died due to neurological complications. Even though the major cause of mortality in Austrian syndrome is cardiac involvement, meningitis is also linked with high morbidity and eventually death. We emphasize the relevance of an early diagnosis of the triad in order to decrease the very high mortality associated with this syndrome.

scholarly journals Clinical and epizootiological study of a leptospirosis outbreak due to Leptospira canicola in a feedlot : case report

1997 ◽  
Vol 68 (3) ◽  
Author(s):  
I. Yeruham ◽  
M. Bernstein ◽  
S. Perl ◽  
S. Irlin ◽  
A. Cohen ◽  
...  
Keyword(s):  
Case Report ◽  
High Mortality ◽  
Clinical Presentation ◽  
Clinical Disease ◽  
Diagnosis And Treatment ◽  
High Morbidity ◽  
Subclinical Infection ◽  
Serological Evidence ◽  
Feedlot Calves

This report describes the epizootiology, clinical presentation, diagnosis and treatment of an outbreak of leptospirosis caused by Leptospira canicola in feedlot calves. The infection appeared to be of high morbidity with a cumulative clinical incidence of 15.6 %, cumulative subclinical incidence of 39 % and high mortality (8.3 %). Clinical disease was diagnosed in 4-8-month-old calves, while subclinical infection occurred in 9-12-month-old calves. Subclinical infection was based on serological evidence only. The zoonotic aspects of the infection are emphasised.

scholarly journals Animal Models of Streptococcus pneumoniae Disease

2008 ◽  
Vol 21 (4) ◽  
pp. 666-685 ◽  
Author(s):  
Damiana Chiavolini ◽  
Gianni Pozzi ◽  
Susanna Ricci
Keyword(s):  
Streptococcus Pneumoniae ◽  
Animal Models ◽  
Otitis Media ◽  
High Mortality ◽  
Research Effort ◽  
Risk Groups ◽  
In Vivo Studies ◽  
High Morbidity ◽  
Pneumococcal Infections

SUMMARY Streptococcus pneumoniae is a colonizer of human nasopharynx, but it is also an important pathogen responsible for high morbidity, high mortality, numerous disabilities, and high health costs throughout the world. Major diseases caused by S. pneumoniae are otitis media, pneumonia, sepsis, and meningitis. Despite the availability of antibiotics and vaccines, pneumococcal infections still have high mortality rates, especially in risk groups. For this reason, there is an exceptionally extensive research effort worldwide to better understand the diseases caused by the pneumococcus, with the aim of developing improved therapeutics and vaccines. Animal experimentation is an essential tool to study the pathogenesis of infectious diseases and test novel drugs and vaccines. This article reviews both historical and innovative laboratory pneumococcal animal models that have vastly added to knowledge of (i) mechanisms of infection, pathogenesis, and immunity; (ii) efficacies of antimicrobials; and (iii) screening of vaccine candidates. A comprehensive description of the techniques applied to induce disease is provided, the advantages and limitations of mouse, rat, and rabbit models used to mimic pneumonia, sepsis, and meningitis are discussed, and a section on otitis media models is also included. The choice of appropriate animal models for in vivo studies is a key element for improved understanding of pneumococcal disease.

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