One year real world prospective follow-up study of a major depressive episode of patients treated with paroxetine and pindolol or paroxetine for 6 weeks

1998 ◽  
Vol 13 (4) ◽  
pp. 169-174 ◽  
Author(s):  
M. B. Tome ◽  
M. T. Isaac
PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e30719 ◽  
Author(s):  
Marianna Virtanen ◽  
Stephen A. Stansfeld ◽  
Rebecca Fuhrer ◽  
Jane E. Ferrie ◽  
Mika Kivimäki

2021 ◽  
pp. 102917
Author(s):  
Kotaro Hatta ◽  
Shigemasa Katayama ◽  
Takuya Ishizuka ◽  
Yasuhiko Sudo ◽  
Mitsuru Nakamura ◽  
...  

2020 ◽  
Vol 3 (3) ◽  
pp. 389-395
Author(s):  
SB Yilleng ◽  
DD Dapap

Amputation may be used to treat a diseased limb or improve its function, and it is considered the last, albeit valuable option when limb salvage is impossible. The decision to amputate a limb is an emotional process for the patient and the patient's family. The result is often loss of economic power of the individual and his/her independence when not sufficiently rehabilitated back into the society. The aim of the study was to determine early psychological outcome of major limb amputation. This was a prospective study, where 54 consenting patients admitted via either the accident and emergency unit or general outpatient clinic of a tertiary hospital for major limb amputation that met the inclusion criteria were recruited into the study consecutively over a period of one year. They were assessed for depression with Mini International Neuropsychiatric Interview (MINI) Instrument, while Rehabilitation outcome was graded using functional independence measure. Intensive counseling with psycho education was commence before amputation and continues after amputation by counselors. Physiotherapy, occupational therapy, coping skills and other life skill training commence after amputation to 3 months of follow up. Only 1 (1.9%) of the respondents was diagnosed with major depressive episode out of the 54 that completed the study. Some of the remaining 53 (98.1%) had few symptoms of depression but did not fulfilled the diagnostic criteria for major depressive episode according to M.I.N.I. The rehabilitation of all the patients were good with a mean functional measure score of 117.59 (sd=3.328) and a P-value of 0.00 at discharge and even after follow up. Our findings show that early and proper rehabilitation of amputees seem to reduce their psychological symptoms. Tendency to get depressed following amputation is more common in the younger age group, female gender and in amputations as a result of trauma while rehabilitation seems better in same and vice versa.


2011 ◽  
Vol 73 (02) ◽  
pp. 185-191 ◽  
Author(s):  
Antonio Ciudad ◽  
Enrique Álvarez ◽  
Miquel Roca ◽  
Enrique Baca ◽  
Luis Caballero ◽  
...  

1999 ◽  
Vol 29 (6) ◽  
pp. 1323-1333 ◽  
Author(s):  
CHRISTINE KUEHNER ◽  
IRIS WEBER

Background. The response styles theory suggests that rumination in response to depressed mood exacerbates and prolongs depression, while distraction ameliorates and shortens it. Gender differences in response styles are said to contribute to the observed gender differences in the prevalence of unipolar depression. While empirical support for the theory has been found from a variety of non-clinical studies, its generalizability to clinically depressed patient populations remains unclear.Methods. A cohort of 52 unipolar depressed in-patients was assessed with the Response Styles Questionnaire during in-patient stay (T1) and 4 weeks after discharge (T2). The patients were followed up 4 months after discharge (T3). Clinical assessment included the SCAN-PSE-10.Results. Moderate and statistically significant retest-stabilities for rumination and distraction were found, comparable for patients with stable and changing depression status from T1 to T2. A cross-sectional diagnosis of a major depressive episode was associated with rumination, while gender was not. Post-discharge baseline rumination (T2), adjusted for concurrent depression, predicted follow-up levels of depression (T3), and, in patients who were non-remitted at post-discharge baseline, it predicted presence of a major depressive episode at follow-up (T3). Results on distraction were more ambiguous.Conclusions. Our results suggest that rumination is likely to have a deteriorating impact on the course of clinical episodes of depression in unipolar depressed patients. Larger longitudinal patient studies are needed to validate these findings.


2014 ◽  
Vol 13 (3) ◽  
pp. 801-807 ◽  
Author(s):  
Johan Sebti ◽  
Françoise Desseigne ◽  
Pierre Saltel

AbstractObjective:Since the description by Yaskin in 1931, it has been observed that pancreatic cancer and depression are two clinical entities that share a high affinity. This observation relies on the higher incidence of depressive syndromes associated with pancreatic cancer than in any other type of digestive tumor, and on the possible occurrence of depressive symptoms several months before the diagnosis of cancer. We present here a series of cases whose screening returned positive for depression-related diagnoses in the months prior to revelation of the cancer.Method:We employed a structured psychiatric interview based on DSM–IV criteria (SCID–I). The diagnoses considered were major depressive episode, minor depressive episode, and subsyndromal depression. All subjects were free of psychiatric history.Results:Some 15 patients were initially included: 10 presented compatible criteria for a past depressive episode, 2 presented a major depressive episode, 4 met the diagnosis of minor depression, and 4 evidenced subsyndromal depression over the one-year period prior to cancer diagnosis.Significance of results:This series of cases is consistent with previous work on the subject that suggested an increased vulnerability to depressive events in the premorbid phase of pancreatic cancer. If the possibility of depressive syndromes constituting the early stages of neoplastic disease is a common idea, it is still impossible to determine the natural history of these two disorders and therefore their causal linkage.


1989 ◽  
Vol 4 (5) ◽  
pp. 315-323 ◽  
Author(s):  
H.U. Wittchen ◽  
C.A. Essau

SummaryThe comorbidity of anxiety disorders and depression, and its effect on course and outcome was examined by using data from the Munich Follow-up Study (MFS). The MFS is a prospective 7 year follow-up study in both a clinical sample of originally 291 former inpatients as well as a representative sample (N = 657) from the general population. Diagnoses were based on the Diagnostic Interview Schedule (DIS) not using the optional DSM-III exclusion rules. Based on earlier studies the temporal relationship of diagnoses was examined by using the age of onset and recency codings of the DIS, correcting for inaccuracies in patients’ judgement. The results showed: 1), Comorbidity seems to be a rather frequent and stable phenomenon in clinical and epidemiological samples. The comorbidity rates of the DIS/DSM-III diagnoses, amounted to about 50% in the epidemiological and 75% in the clinical sample. 2), The majority of the subjects with both disorders indicated an onset of anxiety disorders before that of a major depressive syndrome. None of the cases developed a major depressive episode prior to an anxiety disorder. 3), A less favorable course and outcome was generally found for subjects with both disorders (anxiety and depression), although the predictive value of the diagnostic grouping was meager. Clear differences were found for “pure” disorders (anxiety only, depression only) in the clinical and epidemiological sample. 4), Regardless of whether a depressive episode was present at the time of the follow-up investigation, the mixed group had the worst outcome of all other comparative groups.


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