Pulse pressure is the best predictor of future left ventricular mass and change in left ventricular mass: 10 years of follow-up

2001 ◽  
Vol 19 (11) ◽  
pp. 2047-2054 ◽  
Author(s):  
Jaana M. Jokiniitty ◽  
Silja K. Majahalme ◽  
Mika A. P. Kähönen ◽  
Martti T. Tuomisto ◽  
Väinö M. H. Turjanmaa
Keyword(s):  
Left Ventricular Mass ◽  
Pulse Pressure ◽  
Left Ventricular ◽  
Ventricular Mass

Pulse pressure in tests improves the prediction of left ventricular mass: 10 years of follow-up

2002 ◽  
Vol 22 (3) ◽  
pp. 161-168
Author(s):  
J. Jokiniitty ◽  
S. Majahalme ◽  
M. Kähönen ◽  
M. T. Tuomisto ◽  
V. Turjanmaa
Keyword(s):  
Left Ventricular Mass ◽  
Pulse Pressure ◽  
Left Ventricular ◽  
Ventricular Mass

scholarly journals Impact of Transcendental Meditation on Left Ventricular Mass in African American Adolescents

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Vernon A. Barnes ◽  
Gaston K. Kapuku ◽  
Frank A. Treiber
Keyword(s):  
African American ◽  
Left Ventricular Mass ◽  
Ventricular Remodeling ◽  
Transcendental Meditation ◽  
African American Adolescents ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Cardiovascular Morbidity And Mortality ◽  
Before And After

Background. An early sign of ventricular remodeling is increased left ventricular mass (LVM) which over time may lead to left ventricular hypertrophy, the strongest predictor of cardiovascular morbidity and mortality, other than advancing age.Methods. 62 (30 TM; 32 CTL) African American adolescents (age16.2±1.3years) with high normal systolic BP were randomly assigned to either 4-month Transcendental Meditation (TM) or health education control groups. The echocardiographic-derived measure of LVM index (LVMI = LVM/ht2.7) was measured before and after the 4-month TM study and at 4-month followup. 2D-guided M-mode echocardiography using a Hewlett Packard 5500 echosonograph was used to determine LVMI.Results. The TM group exhibited a greater decrease in LVMI at 4-month followup compared to the CTL group (−2.6 versus +0.3 gm/ht2.7,P<0.04). The TM group exhibited a lesser increase in BMI at 4-month follow-up compared to the CTL group (0.2±1.6versus1.1±1.4,P<0.03).Conclusion. These findings indicate that among a group of prehypertensive African American adolescents, 4 months of TM compared to heath education resulted in a significant decrease in LVMI, and these changes were maintained at 4-month follow-up.

Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism

2020 ◽  
Vol 105 (11) ◽  
Author(s):  
Chieh-Kai Chan ◽  
Wei-Shiung Yang ◽  
Yen-Hung Lin ◽  
Kuo-How Huang ◽  
Ching-Chu Lu ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Clinical Outcome ◽  
Left Ventricular Mass ◽  
Primary Aldosteronism ◽  
Clinical Success ◽  
Multivariate Logistic Regression Analysis ◽  
Left Ventricular ◽  
Secondary Outcome ◽  
Ventricular Mass

Abstract Context The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified. Objective We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy. Design and Patients We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index. Results We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV&lt;1600 cm/sec was significantly associated with complete cure of hypertension. In addition, higher preoperative baPWV was associated with renal function decline and less left ventricular mass regression after adrenalectomy in lateralized PA patients during the follow-up period. Conclusions Our study demonstrated that the preoperative severe arterial stiffness was associated with absent complete clinical success in lateralized PA patients after adrenalectomy, and this effect may contribute to cardiorenal injury, which at least partially explains kidney function deterioration and lessened regression of heart mass.

INDEPENDENT PREDICTORS OF LEFT VENTRICULAR MASS IN SUBJECTS WITH MILD TO MODERATE HYPERTENSION AFTER 6 YEARS OF FOLLOW-UP

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S101-S102
Author(s):  
P. Armario ◽  
T. Casanova ◽  
R. Hernandez-Delrey ◽  
M. Martin-Baranera ◽  
N. Andreu-Valls
Keyword(s):  
Left Ventricular Mass ◽  
Moderate Hypertension ◽  
Left Ventricular ◽  
Ventricular Mass

scholarly journals Left Ventricular Mass in Patients With Type 2 Diabetes Is Independently Associated With Central but not Peripheral Pulse Pressure

Diabetes Care ◽  
2005 ◽  
Vol 28 (4) ◽  
pp. 937-939 ◽  
Author(s):  
J. E. Sharman ◽  
Z. Y. Fang ◽  
B. Haluska ◽  
M. Stowasser ◽  
J. B. Prins ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Left Ventricular Mass ◽  
Pulse Pressure ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Peripheral Pulse

scholarly journals High vitamin K status is prospectively associated with decreased left ventricular mass in women: the Hoorn Study

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Joline W. J. Beulens ◽  
Elisa Dal Canto ◽  
Coen D. A. Stehouwer ◽  
Roger J. M. W. Rennenberg ◽  
Petra J. M. Elders ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Mass ◽  
Vitamin K ◽  
Left Ventricular ◽  
Volume Index ◽  
Left Ventricular Ejection ◽  
Cardiac Structure ◽  
High Vitamin ◽  
Ventricular Mass

Abstract Background Vitamin K is associated with reduced cardiovascular disease risk such as heart failure, possibly by carboxylation of matrix-gla protein (MGP), a potent inhibitor of vascular calcification. The relationship of vitamin K intake or status with cardiac structure and function is largely unknown. Therefore this study aims to investigate the prospective association of vitamin K status and intake with echocardiographic measures. Methods This study included 427 participants from the Hoorn Study, a population-based cohort. Vitamin K status was assessed at baseline by plasma desphospho-uncarboxylated MGP (dp-ucMGP) with higher concentrations reflecting lower vitamin K status. Vitamin K intake was assessed at baseline with a validated food-frequency questionnaire. Echocardiography was performed at baseline and after a mean follow-up time of 7.6, SD=±0.7 years. We used linear regression for the association of vitamin K status and intake with left ventricular ejection fraction (LVEF), left atrial volume index (LAVI) and left ventricular mass index (LVMI), adjusted for potential confounders. Results The mean age was 66.8, SD=±6.1 years (51% were male). A high vitamin K status was prospectively associated with decreased LVMI (change from baseline to follow-up: -5.0, 95% CI: -10.5;0.4 g/m2.7) for the highest quartile compared to the lowest in women (P-interaction sex=0.07). No association was found in men. Vitamin K status was not associated with LVEF or LAVI. Vitamin K intake was not associated with any of the echocardiographic measures. Conclusions This study showed a high vitamin K status being associated with decreased LVMI only in women, while intakes of vitamin K were not associated with any cardiac structure or function measures. These results extend previous findings for a role of vitamin K status to decrease heart failure risk.

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