Renal Excretion of Calcium and Phosphorus in Premature Infants With Incipient Late Metabolic Acidosis

2001 ◽  
Vol 33 (5) ◽  
pp. 565-569 ◽  
Author(s):  
H. Kalhoff ◽  
L. Diekmann ◽  
S. Rudloff ◽  
F. Manz
Keyword(s):  
Metabolic Acidosis ◽  
Premature Infants ◽  
Renal Excretion ◽  
Calcium And Phosphorus ◽  
Incipient Late Metabolic Acidosis

The response of the kidney of the freshwater rainbow trout to true metabolic acidosis

1980 ◽  
Vol 84 (1) ◽  
pp. 227-244 ◽  
Author(s):  
K. A. Kobayashi ◽  
C. M. Wood
Keyword(s):  
Lactic Acid ◽  
Metabolic Acidosis ◽  
Blood Lactate ◽  
Renal Excretion ◽  
Total Acid ◽  
Time Courses ◽  
Lactate Levels ◽  
Urinary Acid ◽  
Proton Load ◽  
Lactate Excretion

Infusion of lactic acid into the bloodstream of trout produced a short-lived depression of blood pH and a long-lasting elevation of blood lactate. The lactate injected was distributed in a volume of 198 ml/kg. Renal excretion of lactate anion and total acid increased by approximately equal amounts during the period of high blood lactate levels, but total renal loss over 72 h accounted for only 2% of the lactate load and 6% of the proton load. Comparable differences in the time courses of blood lactate and pH changes occurred when lactacidosis was induced endogenously by normocapnic hypoxia. The immediate response of the kidney was similar to that with lactic acid infusion, but there was a long-lasting (12–72 + h) elevation of urinary acid efflux that was not associated with lactate excretion. Following hypoxia, renal excretion over 72 h accounted for 1% of the estimated lactate load and 12–25% of the proton load. A renal lactate threshold of 4–10 muequiv/ml prevents significant urinary lactate excretion. The response of the trout kidney to true metabolic acidosis is similar to that of the mammalian kidney.

Late Metabolic Acidosis in Premature Infants.

1965 ◽  
Vol 54 (6) ◽  
pp. 531-540 ◽  
Author(s):  
Poul RANLØV ◽  
Ole SIGGAARD-ANDERSEN
Keyword(s):  
Metabolic Acidosis ◽  
Premature Infants

Renal excretion of hydrogen ions: A defense against acidosis in premature infants

1961 ◽  
Vol 59 (6) ◽  
pp. 848-860 ◽  
Author(s):  
Mitchell I. Rubin ◽  
Philip L. Calcagno ◽  
Barbara L. Ruben
Keyword(s):  
Premature Infants ◽  
Renal Excretion ◽  
Hydrogen Ions

Calcium and phosphorus studies in Negro premature infants

1951 ◽  
Vol 39 (6) ◽  
pp. 677-679 ◽  
Author(s):  
Morris Gleich ◽  
Saul Smoller ◽  
Beatrice E. Scott
Keyword(s):  
Premature Infants ◽  
Calcium And Phosphorus

Effect of metabolic acidosis in intestinal absorption of calcium and phosphorus

1980 ◽  
Vol 239 (6) ◽  
pp. G480-G484 ◽  
Author(s):  
U. Gafter ◽  
J. A. Kraut ◽  
D. B. Lee ◽  
V. Silis ◽  
M. W. Walling ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Acidosis ◽  
Plasma Level ◽  
Intestinal Absorption ◽  
Metabolic Balance ◽  
Vitamin D Metabolism ◽  
Calcium And Phosphorus ◽  
Control Plasma ◽  
P Absorption

To investigate the effect of metabolic acidosis on intestinal calcium (Ca) and phosphorus (P) absorption and vitamin D metabolism, metabolic balance studies and in vitro gut sac uptake of 45Ca and [32P]phosphate were performed in rats maintained on low-Ca and moderately low-P diet and fed NH4Cl for 3 or 9 days and pair-fed controls. Plasma 1,25(OH)2D concentration was measured in the rats fed NH4Cl for 9 days and their controls. Net Ca and P absorption was 87–92% in the acidotic rats and did not differ from control. Moreover, gut sac uptakes of 45Ca and [32P]phosphate were not different from control. Plasma 1,25(OH)2D was higher in the ammonium chloride-fed rats than in controls (213 +/- 44 vs. 110 +/- 12 pg/ml), and serum P was lower in the acidotic animals (4.6 +/- 0.7 vs. 7.6 +/- 0.3 mg/dl). These data indicate that metabolic acidosis does not depress the augmented intestinal absorption of calcium and phosphorus noted during their dietary deprivation nor reduce the plasma level of 1,25(OH)2D.

Zinc in Formulas

PEDIATRICS ◽  
1984 ◽  
Vol 73 (3) ◽  
pp. 412-413
Author(s):  
K. MICHAEL HAMBIDGE
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Clinical Research ◽  
Premature Infants ◽  
Very Low Birth Weight ◽  
Research Center ◽  
Clinical Research Center ◽  
Zinc Concentrations ◽  
Calcium And Phosphorus ◽  
Zinc Balance

To the Editor.— Bhatia and Fomon1 have demonstrated that the quantities of calcium and phosphorus delivered to formula-fed infants may bear little relationship to the label claims. They also warned that, although their report was restricted to these two nutrients, other formula components may also be involved in discrepancies between what is present in the bottle and what is delivered to the infant. Confirmation of this prediction is provided by recent éxperience with measurements of zinc concentrations in Similac Special Care (Ross Laboratories, Columbus, OH) during the course of zinc balance studies on very low-birth-weight premature infants in our neonatal Clinical Research Center.

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