SYNERGISTIC REDUCTION IN LOW-DENSITY LIPOPROTEIN CHOLESTEROL WITH COMBINED HMG-COA REDUCTASE INHIBITOR AND AEROBIC EXERCISE THERAPY IN OBESE, HYPERCHOLESTEROLEMIC MALES

Medicine & Science in Sports & Exercise ◽

10.1097/00005768-200205001-00273 ◽

2002 ◽

Vol 34 (5) ◽

pp. S50

Author(s):

K P. Honeal ◽

I W. Waters ◽

J S. Hallam ◽

J Fullenwider ◽

C McIntosh ◽

...

Keyword(s):

Aerobic Exercise ◽

Exercise Therapy ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Hmg Coa Reductase Inhibitor ◽

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The Relationship Between Apolipoprotein B-100 and Low-Density Lipoprotein Cholesterol after Treatment with an HMG CoA Reductase Inhibitor

American Journal of Clinical Pathology ◽

10.1093/ajcp/92.4.479 ◽

1989 ◽

Vol 92 (4) ◽

pp. 479-483 ◽

Author(s):

Stanley S. Levinson ◽

Roger D. Blevins ◽

Michael P. Smith ◽

Melvin Rubinfire ◽

James J. Maciejko

Keyword(s):

Apolipoprotein B ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Hmg Coa Reductase Inhibitor ◽

Coa Reductase ◽

The Relationship

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Effects of NK-104, a new hydroxymethylglutaryl-coenzyme reductase inhibitor, on low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia

The American Journal of Cardiology ◽

10.1016/s0002-9149(99)00656-6 ◽

2000 ◽

Vol 85 (2) ◽

pp. 178-183 ◽

Author(s):

Kouji Kajinami ◽

Junji Koizumi ◽

Kosei Ueda ◽

Susumu Miyamoto ◽

Tadayoshi Takegoshi ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Heterozygous Familial Hypercholesterolemia

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Ezetimibe Reduces Low-Density Lipoprotein Cholesterol (LDL-C) in Renal Transplant Patients Resistant to HMG-CoA Reductase Inhibitors

American Journal of Therapeutics ◽

10.1097/01.mjt.0000209693.83065.a6 ◽

2007 ◽

Vol 14 (5) ◽

pp. 438-441 ◽

Author(s):

Peale Chuang ◽

Anthony J Langone

Keyword(s):

Renal Transplant ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Transplant Patients ◽

Reductase Inhibitors ◽

Hmg Coa Reductase Inhibitors ◽

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Effects of HMG CoA reductase inhibitor on cholesterol absorption in obesity: Implications for the regulation of very-low-density lipoprotein B-100 metabolism

Atherosclerosis Supplements ◽

10.1016/s1567-5688(02)80779-6 ◽

2002 ◽

Vol 3 (2) ◽

pp. 235

Keyword(s):

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Cholesterol Absorption ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Lowering Low Density Lipoprotein Cholesterol with Simvastatin, a Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor, Does Not Affect Luteal Function in Premenopausal Women

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.87.7.8635 ◽

2002 ◽

Vol 87 (7) ◽

pp. 3155-3161 ◽

Author(s):

Diane Plotkin ◽

Sam Miller ◽

Steven Nakajima ◽

Edward Peskin ◽

Ronald Burkman ◽

...

Keyword(s):

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Premenopausal Women ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Luteal Function ◽

Coenzyme A Reductase

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HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with type-2 diabetes

Life Sciences ◽

10.1016/s0024-3205(02)02038-6 ◽

2002 ◽

Vol 71 (20) ◽

pp. 2403-2412 ◽

Author(s):

Hirohito Sone ◽

Akimitsu Takahashi ◽

Hitoshi Shimano ◽

Shun Ishibashi ◽

Gen Yoshino ◽

...

Keyword(s):

Type 2 Diabetes ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitor, on oxidative modification of human low-density lipoprotein in vitro

Biochemical Pharmacology ◽

10.1016/s0006-2952(98)00341-4 ◽

1999 ◽

Vol 57 (6) ◽

pp. 697-703 ◽

Author(s):

Kuniharu Suzumura ◽

Mikiko Yasuhara ◽

Keiko Tanaka ◽

Toshikazu Suzuki

Keyword(s):

Protective Effect ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Oxidative Modification ◽

Low Density ◽

Hmg Coa Reductase Inhibitor ◽

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Effects of fluvastatin (XU 62-320), an HMG-CoA reductase inhibitor, on the distribution and composition of low density lipoprotein subspecies in humans

Atherosclerosis ◽

10.1016/0021-9150(91)90017-w ◽

1991 ◽

Vol 87 (2-3) ◽

pp. 147-157 ◽

Author(s):

Jiana Yuan ◽

Michael Y. Tsai ◽

Janet Hegland ◽

Donald B. Hunninghake

Keyword(s):

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

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Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy

Atherosclerosis ◽

10.1016/0021-9150(94)05439-p ◽

1995 ◽

Vol 113 (2) ◽

pp. 157-166 ◽

Author(s):

Jose M. Ordovas ◽

Jose Lopez-Miranda ◽

Francisco Perez-Jimenez ◽

Carmen Rodriguez ◽

Jong-Soon Park ◽

...

Keyword(s):

Apolipoprotein E ◽

Reductase Inhibitor ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Inhibitor Therapy ◽

Low Density ◽

Hmg Coa Reductase ◽

Hmg Coa Reductase Inhibitor ◽

Lipoprotein Response ◽

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▾ Pravastatin (lipostat) – another statin for lowering cholesterol

Drug and Therapeutics Bulletin ◽

10.1136/dtb.29.12.47 ◽

1991 ◽

Vol 29 (12) ◽

pp. 47-48

Keyword(s):

Cholesterol Synthesis ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Low Density Lipoprotein Cholesterol ◽

Hmg Coa Reductase ◽

Similar Drug ◽

Coa Reductase ◽

Last year we reviewed simvastatin,1 which lowers total and low-density-lipoprotein cholesterol (LDL-C) in plasma by competitively inhibiting the rate-limiting enzyme in cholesterol synthesis, HMG CoA reductase, in the liver. Pravastatin (Lipostat – Bristol-Myers Squibb) is a similar drug.

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