EFFECTS OF CONTACT LENSES ON REFRACTIVE CORNEAL AND AXIAL LENGTH CHANGES IN YOUNG MYOPES

1969 ◽  
Vol 46 (12) ◽  
pp. 903-911 ◽  
Author(s):  
William R. Baldwin ◽  
Don West ◽  
Jerry Jolley ◽  
William Reid
Vision ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 7
Author(s):  
Craig Wilde ◽  
Mary Awad ◽  
Gavin Orr ◽  
Dharmalingam Kumudhan ◽  
Saker Saker ◽  
...  

To evaluate the incidence of symptomatic anisometropia and aniseikonia requiring intervention following surgery with combined pars plana vitrectomy (PPV) and broad 276 style encircling scleral buckle (ESB) for the repair of rhegmatogenous retinal detachments (RRD) and to report axial length (AL) and keratometry changes, a retrospective review of consecutive RRD patients treated with combined PPV and ESB between June 2016 until September 2019 was performed. All patients with symptomatic optically induced aniseikonia requiring additional interventions or surgical procedures including clear lens exchanges, secondary intraocular lens implants or contact lenses were documented. Keratometry and AL measurements were recorded for each eye and changes calculated. In total, 100 patients underwent combined PPV, ESB and endotamponade with mean age of 59.47 years (SD 11.49). AL was significantly increased (25.39 mm [SD 1.27] to 26.54 mm [SD 1.16], p = 0.0001), with a mean change of 1.15 mm (SD 0.67). Mean corneal astigmatism increased by –0.95 D (SD 0.51) in control eyes preoperatively and –1.33 (SD 0.87) postoperatively (p = 0.03). Over half of phakic patients (39/61; 64%) developed a visually significant cataract, subsequently undergoing surgery. Six of 100 patients developed symptomatic anisometropia with aniseikonia postoperatively (6%). Four proceeded with clear lens exchange despite absence of visually significant cataract (4%). Two of these initially trialled contact lenses (2%). One was intolerant, while the other decided to proceed with clear lens exchange for convenience. Only one patient (1%), being pseudophakic in both eyes, had persistent anisometropia/aniseikonia. AL and keratometry changes induced by encirclement with broad solid silicone rubber buckles are acceptable and similar to those reported previously using narrow encircling components, being unlikely to induce troublesome symptomatic anisometropia/aniseikonia. Many patients are phakic and develop visually significant cataracts, allowing correction of changes induced with the aim of visual restoration. A minority require more prolonged methods of visual rehabilitation, such as contact lens wear or clear lens exchanges. Caution and appropriate consent should be made in patients that are pseudophakic in both eyes at presentation.


2021 ◽  
Vol 10 (4) ◽  
pp. 808
Author(s):  
Cristina Alvarez-Peregrina ◽  
Miguel Ángel Sánchez-Tena ◽  
Clara Martinez-Perez ◽  
Catalina Santiago-Dorrego ◽  
Thomas Yvert ◽  
...  

Background: Many epidemiological and experimental studies have established that myopia is caused by a complex interaction between common genetic and environmental factors. The objective of this study was to describe and compare the allelic and genotypic frequencies of the rs524952 (GJD2), rs8000973 (ZIC2), rs1881492 (CHRNG), rs1656404 (PRSS56), rs235770 (BMP2), and rs7744813 (KCNQ5) SNPs (single-nucleotide polymorphism) between responder and nonresponder patients who had undergone a two-year treatment with lenses for myopia control. Method: Twenty-eight participants from the MiSight Assessment Study Spain (MASS), who had received treatment for myopia control for two years with MiSight contact lenses, were examined. The criteria for better/worse treatment response was the change in the axial length (< / ≥ 0.22 mm two years after the treatment). The clinical procedure consisted of the extraction of a saliva sample, and the participants also underwent an optometric examination. Genetic data were analyzed using SNPStats software (Catalan Institute of Oncology, Barcelona, Spain), and statistical analysis was performed using SPSS v.25 (SPSS Inc., Chicago, IL, USA). Demographic variables were analyzed using the Student’s t-test. Results: The T allele, the one with the lowest frequency, of the “rs235770” SNP was associated with a better treatment response [AL/CR (axial length/corneal radius): OR = 3.37; CI = 1.079–10.886; SE (spherical equivalent): OR = 1.26; CI: = 0.519–57.169; p = 0.019). By performing haplotype analysis, significant differences were found between the rs235770…rs1881492 and rs235770–rs1656404 polymorphisms. The latter presented a strong linkage disequilibrium with each other (r2 ≥ 0.54). Conclusion: The result of lens therapies for myopia control could vary depending on genetic variants. Studies with a larger sample are needed to confirm the results presented in this pilot study.


1993 ◽  
Vol 19 (6) ◽  
pp. 787-788 ◽  
Author(s):  
Robert M. Sinskey ◽  
Juan O. Stoppel ◽  
Pranav A. Amin

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0231208
Author(s):  
Yuan Wu ◽  
Ci Ren Qiong Da ◽  
Jiang Liu ◽  
Xiaoming Yan

2020 ◽  
Vol 40 (6) ◽  
pp. 710-717
Author(s):  
Jos J. Rozema ◽  
Sorcha Ní Dhubhghaill

2019 ◽  
Vol 57 (1) ◽  
pp. 12
Author(s):  
Hemant Sonawane ◽  
Madhu Shekhar ◽  
Haripriya Aravind
Keyword(s):  

2021 ◽  
Author(s):  
Xun Chen ◽  
Zhi Chen ◽  
Huamao Miao ◽  
Xuanqi Wang ◽  
Xiaoying Wang ◽  
...  

Abstract Purpose: To investigate the refractive stability, axial length changes and their related factors in a high myopia population after Implantable Collamer Lens (ICL) implantation.Methods: This prospective study included 116 eyes of 116 patients divided into several groups based on the spherical equivalent refractive error (SE)—SE > -6D, -12 ≤ SE < -6D and SE < -12D groups—and axial length (AL)—AL < 28mm and AL ≥ 28mm groups. The uncorrected and corrected distance visual acuity, refraction, axial length and intraocular pressure were followed for 1 year.Results: SE changed from -11.53 ± 5.25D preoperatively to -0.33 ± 0.70D at 1 week, and further changed to -0.48 ± 0.77D at 1 year after ICL implantation, with average progression being -0.15 ± 0.37D from 1 week to 1 year after surgery. Axial length changed from 27.95 ± 2.33mm preoperatively to 27.98 ± 2.36mm 1 year after surgery, with an average axial elongation of 0.03 ± 0.12mm. The mean axial elongation rate was 0.05mm/year in the SE < -12D group, being significantly faster than the other SE groups (P < 0.05); it was 0.06mm/year in the AL ≥ 28mm group, being significantly faster than the AL < 28mm group (P < 0.05).Conclusion: Patients with high myopia and long axial length showed a continuous myopic progression and axial elongation at an adult age after ICL surgery, especially those with myopia higher than -12.0D and AL longer than 28.00mm.


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