Breast Reconstruction in Women Treated with Radiation Therapy for Breast Cancer

Breast reconstruction after breast cancer is an emotional subject for women. Consequently, the correct timing and surgical procedure for each individual woman are important. In general, heterologous or autologous reconstructive procedures are available, both having advantages and disadvantages. Breast size, patient habitus, and previous surgeries or radiation therapy need to be considered, independent of the chosen procedure. New surgical techniques, refinement of surgical procedures, and the development of supportive materials have increased the general patient collective eligible for breast reconstruction. This review highlights the different approaches to immediate breast reconstruction using autologous or heterologous techniques.

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Validation of Breast Volume Measurement using Non-invasive Surface Scan

Inquiry@Queen's Undergraduate Research Conference Proceedings ◽

10.24908/iqurcp.10314 ◽

2018 ◽

Author(s):

Rachel House

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Standard Deviation ◽

Breast Reconstruction ◽

Volume Loss ◽

Breast Volume ◽

3D Slicer ◽

Reconstruction Surgery ◽

Non Invasive ◽

Surface Scan

ntroduction: Breast Cancer is the most frequently occurring cancer in Canadian women [1]. The standard of care normally involves breast conserving surgery and radiation therapy followed by breast reconstruction surgery. For successful breast reconstruction, the total volume loss must be accounted for. Unfortunately, the volume excised during surgery generally does not reflect total breast volume loss, for example, radiation therapy is known to cause volume loss of the breast [2]. Our goal is to provide the software and workflow necessary to calculate the breast volume using a non-invasive technique. By calculating and comparing the breast volume of the patient before undergoing reconstruction surgery to the baseline volume will help surgeon’s better estimate how much tissue needs to be replaced. Methods: A 3D surface scan of the patient’s chest is obtained. The scan is then imported into 3D Slicer where modules are used to isolate the target breast and calculate the volume . Results: The method provided to calculate breast volume is feasible using 3D Slicer and only requires one surface scan from the patient. The ground truth breast volume of the mannequin was 164mL with a standard deviation of 4.1ml (n=5). The volume of the mannequin’s breast was calculated using the workflow provided, the mean calculated volume was 160.8mL and the standard deviation was 4.7ml (n=4). Conclusion: Using a 3D surface scanner provides a non-invasive and quick way to calculate breast volume. This initial validation suggests this system may be accurate enough to aid the surgeon in the reconstruction process. References [1] Canadian Breast Cancer Society. (2015). Breast Cancer in Canada, 2015. Retrieved from https://www.cbcf.org/ontario/AboutBreastCancerMain/FactsStats/Pages/Breast-Cancer-Canada.asp [2] Haykal, Siba, Colin P. White, and Nicolas A. Guay. "An estimation of volume loss after radiation therapy on free flap breast reconstruction." Plastic and reconstructive surgery 131.6 (2013): 937e-939e.

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Radiation therapy and breast reconstruction

Pacific Medical Journal ◽

10.34215/1609-1175-2020-4-10-14 ◽

2020 ◽

pp. 10-14

Author(s):

V. I. Apanasevich ◽

I. S. Gulian ◽

N. O. Nikiforova ◽

Y. Y. Petukhova ◽

O. V. Korshunova ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Breast Reconstruction ◽

Meta Analysis ◽

The Other ◽

Acellular Matrix ◽

Other Hand ◽

Integral Component ◽

Capsular Contractures

Radiation therapy is an integral component of the treatment of breast cancer. Although its implementing after breast reconstruction sufficiently increases the number of complications, particularly capsular contractures. After having analyzed published materials and meta-analysis research the authors made a conclusion – if a patient is planned to have a breast reconstruction, it’s better to make it with her own tissue. On the other hand the risk of capsular contractures development significantly decreases when using acellular matrix and polyurethane shell to cover the implant. This fact gives hope that conflict between breast reconstruction and the necessity of the radiation therapy can be solved.

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Oncological safety of immediate rectus abdominis myocutaneous breast reconstruction in patients with locally advanced disease (stage IIb and III)

South Asian Journal of Cancer ◽

10.4103/2278-330x.119921 ◽

2013 ◽

Vol 02 (04) ◽

pp. 239-242

Author(s):

Mushtaq Mir ◽

Muddassir Shahdhar ◽

Khurshid Ganaie ◽

Quibtiya Syed

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Breast Reconstruction ◽

Systemic Therapy ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Immediate Breast Reconstruction ◽

Rectus Abdominis ◽

Reconstructed Breast

Abstract Background: The management of locally advanced (Stage IIb and III) breast cancer is challenging. It often includes multimodal treatment with systemic therapy and/or radiation therapy and surgery. Immediate breast reconstruction has not traditionally been performed in these patients. We review the results of immediate rectus abdominis musculo-cutaneous (TRAM/VRAM) flap in 60 patients treated for Stage IIb and III breast cancer. Materials and Methods: Data were collected prospectively on 60 patients diagnosed with Stage IIb (32 patients) and Stage III (28 patients) breast cancer between May 2008 and May 2012. All patients had mastectomy and immediate rectus abdominis myocutaneous reconstruction (TRAM in 40 patients and VRAM in 20 patients). All patients received primary systemic therapy, and all patients received postoperative radiotherapy to the operative site. Results: Mean age was 40.13 (range 28-53) years, mean hospital stay was 8.86 days and mean follow-up for the group was 28 months. Neither of them developed local disease recurrence in the operative site till the last follow-up. Eight (13.3%) patients had some delay in chemo-radiation therapy due to flap-related complications. Flap-related complications were present in eight patients (partial flap failure in four and superficial skin necrosis in four). There was no adverse effect of chemo-radiation therapy on reconstructed breast. Conclusion: Immediate TRAM/VRAM breast reconstruction for locally advanced breast cancer is not associated with a significant delay in adjuvant therapy or an increased risk of local relapse. Radiation therapy can be delivered to the reconstructed breast when indicated without difficulty. Breast reconstruction facilitates surgical resection of locally advanced breast cancer with primary closure and should be considered if the patient desires immediate breast reconstruction.

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The use of xenopericardium in reconstructive surgery in patients with breast cancer

Problems in oncology ◽

10.37469/0507-3758-2021-67-3-374-381 ◽

2021 ◽

Vol 67 (3) ◽

pp. 374-381

Author(s):

Dzerassa Ortabaeva ◽

Aziz Zikiryakhodzhayev ◽

Elena Rasskazova ◽

Erik Saribekyan ◽

Shakhnoz Khakimova ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Breast Reconstruction ◽

Reconstructive Surgery ◽

Clinical Case ◽

Subcutaneous Mastectomy ◽

Good Cosmetic Result ◽

Simultaneous Reconstruction ◽

Good Cosmetic ◽

Lower Slope

Objective: to analyze the possibility of using xenopericardium for breast reconstruction in cancer Materials and methods: the article presents a clinical case of a patient diagnosed with breast cancer who underwent a subcutaneous mastectomy with simultaneous reconstruction with an endoprosthesis and a xenopericardium to strengthen the lower slope of the breast. Results: in our study, a good cosmetic result was obtained, and the presence of xenopericardium does not affect the conduct of postoperative courses of chemotherapy and radiation therapy. Conclusion: we present the first experience of using bovine pericardium in Russia for breast reconstruction in patients with breast cancer. Xenopericardium BioLAB-PP/PA of domestic origin was used to strengthen the lower slope of the reconstructed MJ using a silicone implant.

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