The developmental biology of lymphoid tissue in the rabbit. Consideration of the role of the thymus and appendix

1964 ◽  
Vol 2 (5) ◽  
pp. 680
Author(s):  
O. K. Archer ◽  
D. E. R. Sutherland ◽  
R. A. Good
Author(s):  
Millissia Ben Maamar ◽  
Eric E Nilsson ◽  
Michael K Skinner

Abstract One of the most important developing cell types in any biological system is the gamete (sperm and egg). The transmission of phenotypes and optimally adapted physiology to subsequent generations is in large part controlled by gametogenesis. In contrast to genetics, the environment actively regulates epigenetics to impact the physiology and phenotype of cellular and biological systems. The integration of epigenetics and genetics is critical for all developmental biology systems at the cellular and organism level. The current review is focused on the role of epigenetics during gametogenesis for both the spermatogenesis system in the male and oogenesis system in the female. The developmental stages from the initial primordial germ cell through gametogenesis to the mature sperm and egg are presented. How environmental factors can influence the epigenetics of gametogenesis to impact the epigenetic transgenerational inheritance of phenotypic and physiological change in subsequent generations is reviewed.


Gut and Liver ◽  
2014 ◽  
Vol 8 (6) ◽  
pp. 637-642 ◽  
Author(s):  
Byung-Hoon Min ◽  
Jun Young Park ◽  
Eun Ran Kim ◽  
Yang Won Min ◽  
Jun Haeng Lee ◽  
...  

2000 ◽  
Vol 14 (suppl d) ◽  
pp. 145D-151D ◽  
Author(s):  
M Keith Hanna ◽  
Kenneth A Kudsk

There has been an explosion of research in the field of nutrition over the past quarter century. Clinical studies have demonstrated the effectiveness of providing nutrition by the enteral route in reducing septic morbidity in critically ill patients. These improved outcomes have been substantiated by animal models that show that enteral nutrition decreases gut permeability while maintaining the gut-associated lymphoid tissue (GALT) in mucosal immunity. Evidence points to the important immunological role of the gut in the maintenance of mucosal immunity at both intestinal and extraintestinal sites. The preservation of this mucosal immunity by enteral nutrition is consistent with the lower morbidity seen in severely injured patients who receive nutrition via the gastrointestinal tract. For patients who are unable to be fed by the enteral route and who require parenteral nutrition, several supplements show promise in enhancing the mucosal immune system defenses. The nutritional and pharmacological tactics that may enhance the GALT and thereby maintain mucosal immunity are examined.


Ophthalmology ◽  
2007 ◽  
Vol 114 (1) ◽  
pp. 182-186 ◽  
Author(s):  
Nicolai C. Sjö ◽  
Pia Foegh ◽  
Birgitte R. Juhl ◽  
Hans-Olof Nilsson ◽  
Jan U. Prause ◽  
...  

Virology ◽  
2005 ◽  
Vol 341 (2) ◽  
pp. 313-320 ◽  
Author(s):  
Jan Münch ◽  
Devi Rajan ◽  
Elke Rücker ◽  
Steffen Wildum ◽  
Nadia Adam ◽  
...  

Author(s):  
Giovanni Bruno ◽  
Giulia Rocco ◽  
Piera Zaccari ◽  
Barbara Porowska ◽  
Maria Teresa Mascellino ◽  
...  

Helicobacter pylori (Hp) is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Hp colonization modifies the composition of gastric microbiota that could drive the development of gastric disorders. Currently, an emerging problem in Hp treatment is represented by the increasing rate of antimicrobial therapy resistance. In this context, the search for adjuvant agents can be very useful to overcome this issue and probiotics administration can represent a valid option. The aim of this review is to describe the gastric microbiota changes during Hp colonization, the mechanisms of action, and a possible role of probiotics in the treatment of this infection.


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