IN VITRO INDUCTION OF ENDOTHELIAL HLA CLASS II ANTIGEN EXPRESSION BY CYTOMEGALOVIRUS-ACTIVATED CD4+ T CELLS1

1993 ◽  
Vol 56 (6) ◽  
pp. 1504-1512 ◽  
Author(s):  
W. James Waldman ◽  
DEBORAH A. KNIGHT ◽  
PATRICK W. ADAMS ◽  
CHARLES G. OROSZ ◽  
DANIEL D. SEDMAK
The Lancet ◽  
1991 ◽  
Vol 338 (8778) ◽  
pp. 1344 ◽  
Author(s):  
Csaba Balázs ◽  
Agota Bokk ◽  
Edith Bodolay ◽  
NadirR. Farid

2003 ◽  
Vol 27 (3) ◽  
pp. 151-155 ◽  
Author(s):  
Dhiraj Abhyankar ◽  
Sundaram Amirtha Lakshmi ◽  
Vaijayanthi Pushparaj ◽  
Jyotirmay Biswas ◽  
Subramanian Krishnakumar

1987 ◽  
Vol 116 (1_Suppl) ◽  
pp. S21-S26 ◽  
Author(s):  
B. E. Wenzel ◽  
H. Arnholdt ◽  
S. Grammerstorf ◽  
R. Gutekunst ◽  
P. C. Scriba

Abstract. The modulation of HLA-D expression of thyroid epithelial cells (TEC) was studied in vitro by means of immunofluorescence. Under serum-free culture conditions, TSH and TSH-receptor antibodies induce HLA-D on TECs derived from GD-patients. Serum-free culture conditions provide a higher availability of TSH-receptors by a 'right side right' polarity of the cellular morphology. There was no evidence for IFN-γ producing cell contaminations on GD-TECs. TSH in contrast to IFN-γ does not induce HLA-DQ on TECs. HLA-DQ is not displayed by spontaneously class-II antigen expressing GD-TECs. Methimazole as well as perchlorate do not suppress HLA-D expression of TECs.


1985 ◽  
Vol 40 (1) ◽  
pp. 21-24 ◽  
Author(s):  
G. GROENEWEGEN ◽  
W. A. BUURMAN ◽  
G. M.A.A. JEUNHOMME ◽  
C. J. VAN DER LINDEN

1985 ◽  
Vol 35 (2) ◽  
pp. 245-250 ◽  
Author(s):  
Reinhard Schwartz ◽  
Frank Momburg ◽  
Gerhard Moldenhauer ◽  
Bernd Dörken ◽  
Volker Schirrmacher

1989 ◽  
Vol 169 (1) ◽  
pp. 351-356 ◽  
Author(s):  
V Lotteau ◽  
J Sands ◽  
L Teyton ◽  
P Turmel ◽  
D Charron ◽  
...  

In the human there are three isotypic forms of MHC class II gene products (HLA-DR, -DQ, and -DP). The isotype-matched alpha-beta dimers are predominant but isotype-mismatched dimers can also be expressed (DR alpha-DQ beta). Here it is shown that the expression of the DR alpha-DQ beta dimer can be correlated to a high ratio of DR alpha/DR beta mRNA. The DR alpha chain expression was modulated by transfection of a sense and antisense DR alpha cDNA. Overexpression of DR alpha promoted the appearance of the DR alpha-DQ beta dimer. On the other hand, pre-existing DR alpha-DQ beta dimer expression was suppressed after antisense DR alpha cDNA transfection. Therefore, imbalanced expression of the alpha and beta chain from a given isotype could lead to the modification of HLA class II phenotype.


1988 ◽  
Vol 12 (4) ◽  
pp. 299-303
Author(s):  
Massimo Aglietta ◽  
Wanda Piacibello ◽  
Alessandra Stacchini ◽  
Fiorella Sanavio ◽  
Vittorio Infelise ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document