ABSTRACT
The double intravenous glucose tolerance test does not modify the assimilation coefficient in normal and thin diabetic subjects.
On the contrary, in fat diabetic subjects the second coefficient of assimilation increases significantly, but not the first one.
From these researches it is evident that the valuation of glucose assimilation by double venous hyperglycaemic test indicates the functional behaviour of the pancreas in different diabetic states.
The interpretation of this behaviour of pancreatic islet response to the double venous hyperglycaemic test is discussed.