Maternal Weight Gain and Risk of Cesarean Delivery in Women With Class III Obesity [28N]

2019 ◽  
Vol 133 (1) ◽  
pp. 158S-158S
Author(s):  
Emily S. Reiff ◽  
Ann Robin Tucker ◽  
Haywood L. Brown ◽  
Luke Gatta ◽  
Lamani Adkins ◽  
...  
Author(s):  
Ann R. Tucker ◽  
Haywood L. Brown ◽  
Sarah K. Dotters-Katz

Abstract Objective The aim of this study is to describe the impact of maternal weight gain on infant birth weight among women with Class III obesity. Study Design Retrospective cohort of women with body mass index (BMI) ≥40 kg/m2 at initial prenatal visit, delivered from July 2013 to December 2017. Women presenting 14/0 weeks of gestational age (GA), delivering preterm, or had multiples or major fetal anomalies excluded. Maternal demographics and complications, intrapartum events, and neonatal outcomes abstracted. Primary outcomes were delivery of large for gestational age or small for gestational age (SGA) infant. Bivariate statistics used to compare women gaining less than Institute of Medicine (IOM) recommendations (LTR) and women gaining within recommendations (11–20 pounds/5–9.1 kg) (at recommended [AR]). Regression models used to estimate odds of primary outcomes. Results Of included women (n = 230), 129 (56%) gained LTR and 101 (44%) gained AR. In sum, 71 (31%) infants were LGA and 2 (0.8%) were SGA. Women gaining LTR had higher median entry BMI (46 vs. 43, p < 0.01); other demographics did not differ. LTR women were equally likely to deliver an LGA infant (29 vs. 34%, p = 0.5) but not more likely to deliver an SGA infant (0.8 vs. 1%, p > 0.99). After controlling for confounders, the AOR of an LGA baby for LTR women was 0.79 (95% CI: 0.4–1.4). Conclusion In this cohort of morbidly obese women, gaining less than IOM recommendations did not impact risk of having an LGA infant, without increasing risk of an SGA infant.


2019 ◽  
Vol 133 (1) ◽  
pp. 39S-39S
Author(s):  
Emily S. Reiff ◽  
Lamani Adkins ◽  
Ann Robin Tucker ◽  
Luke Gatta ◽  
Haywood L. Brown ◽  
...  

Author(s):  
Ravyn Njagu ◽  
LaMani Adkins ◽  
Ann Tucker ◽  
Luke Gatta ◽  
Haywood L. Brown ◽  
...  

2011 ◽  
Vol 204 (1) ◽  
pp. S117
Author(s):  
Yinka Oyelese ◽  
Revital Faro ◽  
Joseph Canterino ◽  
Candadai Ananth ◽  
Joaquin Santolaya-Forgas

1998 ◽  
Vol 79 (02) ◽  
pp. 328-330 ◽  
Author(s):  
D. Wright ◽  
J. M. Thomson ◽  
A. Sidebotham ◽  
C. F. Hirst ◽  
P. Hirsch ◽  
...  

SummaryA longitudinal study of 21 pregnant women has been undertaken using a variety of factor VII assays, including factor VIIa, to investigate the increase of factor VIIc. All assays demonstrated significant rises (p <0.001), most marked for factor VIIa (82%) and factor VIIc rabbit (81%). Smaller rises were seen for factor VIIc bovine (50%) and VII antigen (40%). Three indirect measures of activity state, factor VIIc rabbit:antigen, bovine:antigen and bovine:rabbit, provided conflicting data. Factor VIIa:antigen showed a significant increase of 36% (p <0.001). Within individual pregnancies the change in factor VIIc rabbit and antigen correlated with maternal weight gain (p <0.05). Two activity state measures, bovine:rabbit and bovine:antigen, showed negative correlation with birthweight. The increases in both zymogen and in activity state appear to contribute to the factor VIIc rise. The extent of this rise appears to be influenced by maternal weight gain. Increased factor VII activation is associated with reduced foetal growth.


2018 ◽  
Vol 36 (05) ◽  
pp. 449-454
Author(s):  
Daniel Pasko ◽  
Kathryn Miller ◽  
Victoria Jauk ◽  
Akila Subramaniam

Objective We sought to evaluate differences in pregnancy outcomes following early amniotomy in women with class III obesity (body mass index ≥40 kg/m2) undergoing induction of labor. Study Design This is a retrospective cohort study of women with class III obesity undergoing term induction of labor from January 2007 to February 2013. Early amniotomy was defined as artificial membrane rupture at less than 4 cm cervical dilation. The primary outcome was cesarean delivery. Secondary outcomes included length of labor, a maternal morbidity composite, and a neonatal morbidity composite. A subgroup analysis examined the effect of parity. Multivariable logistic regression was used to adjust for covariates. Results Of 285 women meeting inclusion criteria, 107 (37.5%) underwent early amniotomy and 178 (62.5%) underwent late amniotomy. Early amniotomy was associated with cesarean delivery after multivariable adjustments (adjusted odds ratio [aOR], 2.05; 95% confidence interval [CI], 1.21–3.47). There were no significant differences in length of labor or maternal and neonatal morbidity between groups. When stratified by parity, early amniotomy was associated with increased cesarean delivery (aOR, 3.10; 95% CI, 1.47–6.58) only in nulliparous women. Conclusion Early amniotomy among class III obese women, especially nulliparous women, undergoing labor induction may be associated with an increased risk of cesarean delivery.


2015 ◽  
Vol 4 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Catherine R. Hankey

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