Can single nucleotide polymorphisms in innate immune receptors predict development of septic complications in intensive care unit patients?*

2005 ◽  
Vol 33 (3) ◽  
pp. 695-696 ◽  
Author(s):  
Jacob E. Wang
PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e77846 ◽  
Author(s):  
Guanghui Yi ◽  
Volker P. Brendel ◽  
Chang Shu ◽  
Pingwei Li ◽  
Satheesh Palanathan ◽  
...  

2015 ◽  
Vol 9 (1) ◽  
pp. 367-371
Author(s):  
Maarten W.G.A. Bronkhorst ◽  
Peter Patka ◽  
Esther M.M. Van Lieshout

Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma. There is increasing evidence for the role of genetic variation in the innate immune system on infectious complications in severe trauma patients. We describe a trauma patient with multiple infectious complications caused by multiple micro-organisms leading to prolonged hospital stay with numerous treatments. This patient had multiple single nucleotide polymorphisms (SNPs) in the MBL2, MASP2, FCN2 and TLR2 genes, most likely contributing to increased susceptibility and severity of infectious disease.


2013 ◽  
Vol 52 (4) ◽  
pp. 497-506 ◽  
Author(s):  
Claire Vignette Mulholland ◽  
Andrew Alexander Somogyi ◽  
Daniel Thomas Barratt ◽  
Janet Kristie Coller ◽  
Mark Rowland Hutchinson ◽  
...  

eJHaem ◽  
2021 ◽  
Author(s):  
Natália Lima Pessoa ◽  
Lilian Martins Oliveira Diniz ◽  
Adriana de Souza Andrade ◽  
Erna Geessien Kroon ◽  
Aline Almeida Bentes ◽  
...  

2010 ◽  
Vol 34 (8) ◽  
pp. S75-S75
Author(s):  
Weifeng Zhu ◽  
Zhuoqi Liu ◽  
Daya Luo ◽  
Xinyao Wu ◽  
Fusheng Wan

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