1574: OUTCOMES OF HEMORRHAGIC INTRACRANIAL LESIONS IN PEDIATRIC PATIENTS SECONDARY TO TRAUMA

AbstractWe aimed to compare accelerated post-contrast magnetization-prepared rapid gradient-echo (MPRAGE) using wave-controlled aliasing in parallel imaging (wave-CAIPI) with conventional MPRAGE as a reliable method to diagnose intracranial lesions in pediatric patients. A total of 23 consecutive pediatric patients who underwent post-contrast wave-CAIPI and conventional MPRAGE (scan time: 2 min 39 s vs. 5 min 46 s) were retrospectively evaluated. Two radiologists independently assessed each image for the presence of intracranial lesions. Quantitative [contrast-to-noise ratio (CNR), contrast rate (CR), and signal-to-noise ratio (SNR)] and qualitative parameters (overall image quality, gray-white matter differentiation, demarcation of basal ganglia and sulci, and motion artifacts) were also surveyed. Wave-CAIPI MPRAGE and conventional MPRAGE detected enhancing and non-enhancing intracranial lesions with 100% agreement. Although wave-CAIPI MPRAGE had a lower SNR (all p < 0.05) and overall image quality (overall analysis, p = 0.02) compared to conventional MPRAGE, other quantitative (CNR and CR) and qualitative parameters (gray-white differentiation, demarcation of basal ganglia and sulci, and motion artifacts) were comparable in the pooled analysis and between both observers (all p > 0.05). Wave-CAIPI MPRAGE was a reliable method for diagnosing intracranial lesions in pediatric patients as conventional MPRAGE at half the scan time.

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Computed tomography-guided stereotactic biopsy of intracranial lesions in pediatric patients

Child s Nervous System ◽

10.1007/s00381-011-1534-6 ◽

2011 ◽

Vol 27 (12) ◽

pp. 2145-2148 ◽

Cited By ~ 3

Author(s):

Ali Meshkini ◽

Sohrab Shahzadi ◽

Alireza Zali ◽

Khosro Parsa ◽

Aimaz Afrough ◽

...

Keyword(s):

Computed Tomography ◽

Pediatric Patients ◽

Stereotactic Biopsy ◽

Intracranial Lesions

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Reference ranges for neuroprotein S-100B: from infants to adolescents

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm.2008.262 ◽

2008 ◽

Vol 46 (9) ◽

Cited By ~ 17

Author(s):

Christoph Castellani ◽

Tatjana Stojakovic ◽

Martin Cichocki ◽

Hubert Scharnagl ◽

Wolfgang Erwa ◽

...

Keyword(s):

Brain Injuries ◽

Pediatric Patients ◽

Head Injuries ◽

Reference Level ◽

Reference Ranges ◽

Healthy Children ◽

X Rays ◽

Intracranial Lesions ◽

History Of ◽

High Doses

Abstract: Diagnosis and treatment of mild traumatic brain injuries in children are especially problematic. At present, computed tomography (CT) is the standard method to identify if patients with intracranial lesions require inpatient monitoring. CT, however, involves exposure to high doses of X-rays, which should be avoided if possible. In adults, the serum level of neuroprotein S-100B has already been proven to be effective for the selection of patients requiring CT. The aim of the present study was to determine reference ranges for serum S-100B in a large number of healthy children.: All patients younger than 18 years with no recent history of head injuries presenting for routine operations were included in the study.: A total of 394 patients were evaluated. In children from 3 to 18 years an upper reference level of 0.16 μg/L was determined. There was a strong inverse relation between age and S-100B in patients younger than 3 years. As the values in this age group were scattered and the number of cases limited (n=65), no reference range could be calculated.: This study provides S-100B reference ranges for pediatric patients based on the largest group of healthy pediatric patients yet analyzed.Clin Chem Lab Med 2008;46:1296–9.

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Audiology Service Models in a Family Physician Practice Setting

Perspectives on Audiology ◽

10.1044/poa6.1.24 ◽

2010 ◽

Vol 6 (1) ◽

pp. 24-32 ◽

Cited By ~ 2

Author(s):

Sridhar Krishnamurti

Keyword(s):

Pediatric Patients ◽

Practice Patterns ◽

Healthcare Delivery ◽

Direct Consequence ◽

Direct Access ◽

Practice Setting ◽

Pediatric Populations ◽

Family Practice Physicians ◽

Primary Focus ◽

Balance Problems

This article illustrates the potential of placing audiology services in a family physician’s practice setting to increase referrals of geriatric and pediatric patients to audiologists. The primary focus of family practice physicians is the diagnosis/intervention of critical systemic disorders (e.g., cardiovascular disease, diabetes, cancer). Hence concurrent hearing/balance disorders are likely to be overshadowed in such patients. If audiologists get referrals from these physicians and have direct access to diagnose and manage concurrent hearing/balance problems in these patients, successful audiology practice patterns will emerge, and there will be increased visibility and profitability of audiological services. As a direct consequence, audiological services will move into the mainstream of healthcare delivery, and the profession of audiology will move further towards its goals of early detection and intervention for hearing and balance problems in geriatric and pediatric populations.

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