Chronic Kidney Disease Associated with Increased Renal Cancer Risk

2012 ◽  
Vol 34 (8) ◽  
pp. 34
Author(s):  
Rabiya S. Tuma
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cancer Risk ◽  
Renal Cancer

scholarly journals Diabetes, chronic kidney disease and cancer risk

2012 ◽  
Vol 27 (8) ◽  
pp. 3018-3020 ◽  
Author(s):  
A. Hartmann ◽  
T. Jenssen ◽  
H. Holdaas
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cancer Risk

Prevalence of baseline chronic kidney disease in 2,769 Chinese patients with renal cancer: Nephron-sparing treatment is still underutilized

2013 ◽  
Vol 32 (4) ◽  
pp. 1027-1031 ◽  
Author(s):  
Kai-wei Yang ◽  
Geng-yan Xiong ◽  
Xue-song Li ◽  
Yuan Tang ◽  
Qi Tang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Cancer ◽  
Chinese Patients ◽  
Nephron Sparing

scholarly journals PD07-07 CHRONIC KIDNEY DISEASE PRIMARILY RELATED TO RENAL CANCER SURGERY: IMPLICATIONS FOR SURVIVAL

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Jitao Wu ◽  
Chalairat Suk-Ouichai ◽  
Wen Dong ◽  
Elvis R. Caraballo ◽  
Ithaar H. Derweesh ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Cancer ◽  
Cancer Surgery

scholarly journals DNA Damage in Chronic Kidney Disease: Evaluation of Clinical Biomarkers

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Nicole Schupp ◽  
Helga Stopper ◽  
August Heidland
Keyword(s):  
Chronic Kidney Disease ◽  
Dna Damage ◽  
Kidney Disease ◽  
Cancer Risk ◽  
Chromosomal Abnormalities ◽  
Micronucleus Assay ◽  
Dna Lesions ◽  
Clinical Biomarkers ◽  
Modified Dna ◽  
The Impact

Patients with chronic kidney disease (CKD) exhibit an increased cancer risk compared to a healthy control population. To be able to estimate the cancer risk of the patients and to assess the impact of interventional therapies thereon, it is of particular interest to measure the patients’ burden of genomic damage. Chromosomal abnormalities, reduced DNA repair, and DNA lesions were found indeed in cells of patients with CKD. Biomarkers for DNA damage measurable in easily accessible cells like peripheral blood lymphocytes are chromosomal aberrations, structural DNA lesions, and oxidatively modified DNA bases. In this review the most common methods quantifying the three parameters mentioned above, the cytokinesis-block micronucleus assay, the comet assay, and the quantification of 8-oxo-7,8-dihydro-2′-deoxyguanosine, are evaluated concerning the feasibility of the analysis and regarding the marker’s potential to predict clinical outcomes.

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