401 TELMISARTAN PREVENTS COGNITIVE DECLINE IN TYPE 2 DIABETIC MICE WITH IMPROVEMENT OF BLOOD-BRAIN BARRIER DISRUPTION PARTLY DUE TO PPAR-GAMMA ACTIVATION

Type 2 Diabetic

O2-05-05: PPAR-gamma activation with AT1 receptor blockade prevents blood-brain barrier disruption and cognitive impairment in type 2 diabetic mellitus mice

Alzheimer s & Dementia ◽

10.1016/j.jalz.2012.05.652 ◽

2012 ◽

Vol 8 (4S_Part_7) ◽

pp. P244-P244

Author(s):

Masaki Mogi ◽

Li-Juan Min ◽

Jun Iwanami ◽

Kana Tsukuda ◽

Masatsugu Horiuchi

Keyword(s):

Cognitive Impairment ◽

Ppar Gamma ◽

Receptor Blockade ◽

Diabetic Mellitus ◽

Gamma Activation ◽

Type 2 Diabetic Mellitus ◽

Type 2 Diabetic

Peroxisome Proliferator-Activated Receptor-γ Activation With Angiotensin II Type 1 Receptor Blockade Is Pivotal for the Prevention of Blood-Brain Barrier Impairment and Cognitive Decline in Type 2 Diabetic Mice

Hypertension ◽

10.1161/hypertensionaha.112.192401 ◽

2012 ◽

Vol 59 (5) ◽

pp. 1079-1088 ◽

Cited By ~ 67

Author(s):

Li-Juan Min ◽

Masaki Mogi ◽

Masachika Shudou ◽

Fei Jing ◽

Kana Tsukuda ◽

...

Keyword(s):

Angiotensin Ii ◽

Cognitive Decline ◽

Blood Brain Barrier ◽

Peroxisome Proliferator ◽

Receptor Blockade ◽

Diabetic Mice ◽

Peroxisome Proliferator Activated Receptor ◽

Type 2 Diabetic

Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?

Neuroscience Letters ◽

10.1016/j.neulet.2017.05.059 ◽

2017 ◽

Vol 653 ◽

pp. 152-158 ◽

Cited By ~ 13

Author(s):

Ravi K. Sajja ◽

Shikha Prasad ◽

Suni Tang ◽

Mohammad A. Kaisar ◽

Luca Cucullo

Keyword(s):

Blood Brain Barrier ◽

Brain Barrier ◽

Diabetic Mice ◽

Barrier Disruption ◽

Blood Brain ◽

Blood–Brain Barrier Disruption and Neurovascular Unit Dysfunction in Diabetic Mice: Protection with the Mitochondrial Carbonic Anhydrase Inhibitor Topiramate

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.116.237057 ◽

2016 ◽

Vol 359 (3) ◽

pp. 452-459 ◽

Cited By ~ 31

Author(s):

Therese S. Salameh ◽

Gul N. Shah ◽

Tulin O. Price ◽

Melvin R. Hayden ◽

William A. Banks

Keyword(s):

Carbonic Anhydrase ◽

Blood Brain Barrier ◽

Neurovascular Unit ◽

Carbonic Anhydrase Inhibitor ◽

Brain Barrier ◽

Diabetic Mice ◽

Barrier Disruption ◽

Blood Brain ◽

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

The Journals of Gerontology Series A ◽

10.1093/gerona/glx177 ◽

2017 ◽

Vol 73 (7) ◽

pp. 853-863 ◽

Cited By ~ 48

Author(s):

Stefano Tarantini ◽

M Noa Valcarcel-Ares ◽

Andriy Yabluchanskiy ◽

Zsuzsanna Tucsek ◽

Peter Hertelendy ◽

...

Keyword(s):

Oxidative Stress ◽

Gene Expression ◽

Cognitive Decline ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Barrier Disruption ◽

Blood Brain ◽

Neurovascular Dysfunction

Obesity in Aging Exacerbates Blood Brain Barrier Disruption and Neuroinflammation Leading to Synaptic Plasticity Deficit and Cognitive Decline in Mice

The FASEB Journal ◽

10.1096/fasebj.29.1_supplement.789.5 ◽

2015 ◽

Vol 29 (S1) ◽

Author(s):

Zsuzsanna Tucsek ◽

Peter Toth ◽

Stefano Tarantini ◽

Marta Noa Valcarcel‐Ares ◽

Tripti Gautam ◽

...

Keyword(s):

Synaptic Plasticity ◽

Cognitive Decline ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Barrier Disruption ◽

Blood Brain ◽

Ultraearly reperfusion induces blood brain barrier disruption during focal ischemia in rats

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/sj.jcbfm.9591524.0274 ◽

2005 ◽

Vol 25 (1_suppl) ◽

pp. S274-S274

Author(s):

Johannes Woitzik ◽

Axel Hohenstein ◽

Nina Weinzierl ◽

Lothar Schilling

Keyword(s):

Blood Brain Barrier ◽

Focal Ischemia ◽

Brain Barrier ◽

Barrier Disruption ◽

Blood Brain ◽

The treatment of brain metastasis from breast cancer, role of blood-brain barrier disruption and early experience with trastuzumab

Therapy ◽

10.1586/14750708.3.1.97 ◽

2006 ◽

Vol 3 (1) ◽

pp. 97-112 ◽

Cited By ~ 2

Author(s):

Rose Marie Tyson ◽

Dale F Kraemer ◽

Matthew A Hunt ◽

Leslie L Muldoon ◽

Peter Orbay ◽

...

Keyword(s):

Breast Cancer ◽

Brain Metastasis ◽

Blood Brain Barrier ◽

Early Experience ◽

Brain Barrier ◽

Barrier Disruption ◽

Blood Brain ◽

SUBACUTE BLOOD-BRAIN BARRIER DISRUPTION PREDICTS FUNCTIONAL OUTCOME IN THROMBOLYSED STROKE PATIENTS

10.26226/morressier.58e389aed462b80292385739 ◽

2017 ◽

Author(s):

Richard Leigh

Keyword(s):

Functional Outcome ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Stroke Patients ◽

Barrier Disruption ◽

Blood Brain ◽

Faculty Opinions recommendation of Delayed increases in microvascular pathology after experimental traumatic brain injury are associated with prolonged inflammation, blood-brain barrier disruption, and progressive white matter damage.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718287628.793522264 ◽

2016 ◽

Author(s):

Robert Ruff

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

White Matter ◽

Blood Brain Barrier ◽

White Matter Damage ◽

Barrier Disruption ◽

Microvascular Pathology ◽

Experimental Traumatic Brain Injury