Re: Diagnostic Accuracy of Third-Generation Dual-Source Dual-Energy CT: A Prospective Trial and Protocol for Clinical Implementation

2019 ◽  
Vol 201 (3) ◽  
pp. 437-437
Author(s):  
Dean G. Assimos
Keyword(s):  
Diagnostic Accuracy ◽  
Prospective Trial ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Clinical Implementation ◽  
Dual Source

Diagnostic accuracy of third-generation dual-source dual-energy CT: a prospective trial and protocol for clinical implementation

2018 ◽  
Vol 37 (4) ◽  
pp. 735-741 ◽  
Author(s):  
Tim Nestler ◽  
Kai Nestler ◽  
Andreas Neisius ◽  
Hendrik Isbarn ◽  
Christopher Netsch ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Prospective Trial ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Clinical Implementation ◽  
Dual Source

scholarly journals Assessment of thoracic disk herniation by using virtual noncalcium dual-energy CT in comparison with standard grayscale CT

2021 ◽  
Author(s):  
Vitali Koch ◽  
Ibrahim Yel ◽  
Leon D. Grünewald ◽  
Sebastian Beckers ◽  
Iris Burck ◽  
...  
Keyword(s):  
Image Quality ◽  
Diagnostic Accuracy ◽  
Dual Energy ◽  
Spinal Nerve ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Spinal Nerve Root ◽  
Disk Herniation ◽  
Diagnostic Confidence ◽  
Dual Source

Abstract Objectives To determine the diagnostic accuracy of dual-energy CT (DECT) virtual noncalcium (VNCa) reconstructions for assessing thoracic disk herniation compared to standard grayscale CT. Methods In this retrospective study, 87 patients (1131 intervertebral disks; mean age, 66 years; 47 women) who underwent third-generation dual-source DECT and 3.0-T MRI within 3 weeks between November 2016 and April 2020 were included. Five blinded radiologists analyzed standard DECT and color-coded VNCa images after a time interval of 8 weeks for the presence and degree of thoracic disk herniation and spinal nerve root impingement. Consensus reading of independently evaluated MRI series served as the reference standard, assessed by two separate experienced readers. Additionally, image ratings were carried out by using 5-point Likert scales. Results MRI revealed a total of 133 herniated thoracic disks. Color-coded VNCa images yielded higher overall sensitivity (624/665 [94%; 95% CI, 0.89–0.96] vs 485/665 [73%; 95% CI, 0.67–0.80]), specificity (4775/4990 [96%; 95% CI, 0.90–0.98] vs 4066/4990 [82%; 95% CI, 0.79–0.84]), and accuracy (5399/5655 [96%; 95% CI, 0.93–0.98] vs 4551/5655 [81%; 95% CI, 0.74–0.86]) for the assessment of thoracic disk herniation compared to standard CT (all p < .001). Interrater agreement was excellent for VNCa and fair for standard CT (ϰ = 0.82 vs 0.37; p < .001). In addition, VNCa imaging achieved higher scores regarding diagnostic confidence, image quality, and noise compared to standard CT (all p < .001). Conclusions Color-coded VNCa imaging yielded substantially higher diagnostic accuracy and confidence for assessing thoracic disk herniation compared to standard CT. Key Points • Color-coded VNCa reconstructions derived from third-generation dual-source dual-energy CT yielded significantly higher diagnostic accuracy for the assessment of thoracic disk herniation and spinal nerve root impingement compared to standard grayscale CT. • VNCa imaging provided higher diagnostic confidence and image quality at lower noise levels compared to standard grayscale CT. • Color-coded VNCa images may potentially serve as a viable imaging alternative to MRI under circumstances where MRI is unavailable or contraindicated.

Trends in radiation dose and image quality for pediatric patients with a multidetector CT and a third-generation dual-source dual-energy CT

2019 ◽  
Vol 124 (8) ◽  
pp. 745-752 ◽  
Author(s):  
Andrea Agostini ◽  
Alberto Mari ◽  
Cecilia Lanza ◽  
Nicolo’ Schicchi ◽  
Alessandra Borgheresi ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Pediatric Patients ◽  
Multidetector Ct ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Dual Source

scholarly journals Characterization of Urinary Stone Composition by Use of Third-Generation Dual-Source Dual-Energy CT With Increased Spectral Separation

2015 ◽  
Vol 205 (6) ◽  
pp. 1203-1207 ◽  
Author(s):  
Xinhui Duan ◽  
Zhoubo Li ◽  
Lifeng Yu ◽  
Shuai Leng ◽  
Ahmed F. Halaweish ◽  
...  
Keyword(s):  
Urinary Stone ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Stone Composition ◽  
Spectral Separation ◽  
Dual Source

scholarly journals Diagnostic accuracy of color-coded virtual noncalcium reconstructions derived from portal venous phase dual-energy CT in the assessment of lumbar disk herniation

2021 ◽  
Author(s):  
Vitali Koch ◽  
Moritz H. Albrecht ◽  
Leon D. Gruenewald ◽  
Ibrahim Yel ◽  
Katrin Eichler ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Disk Herniation ◽  
Lumbar Disk Herniation ◽  
Portal Venous Phase ◽  
Lumbar Disk ◽  
Contrast Enhanced ◽  
Dual Source ◽  
Venous Phase

Abstract Objectives To investigate the diagnostic accuracy of color-coded contrast-enhanced dual-energy CT virtual noncalcium (VNCa) reconstructions for the assessment of lumbar disk herniation compared to unenhanced VNCa imaging. Methods A total of 91 patients were retrospectively evaluated (65 years ± 16; 43 women) who had undergone third-generation dual-source dual-energy CT and 3.0-T MRI within an examination interval up to 3 weeks between November 2019 and December 2020. Eight weeks after assessing unenhanced color-coded VNCa reconstructions for the presence and degree of lumbar disk herniation, corresponding contrast-enhanced portal venous phase color-coded VNCa reconstructions were independently analyzed by the same five radiologists. MRI series were additionally analyzed by one highly experienced musculoskeletal radiologist and served as reference standard. Results MRI depicted 210 herniated lumbar disks in 91 patients. VNCa reconstructions derived from contrast-enhanced CT scans showed similar high overall sensitivity (93% vs 95%), specificity (94% vs 95%), and accuracy (94% vs 95%) for the assessment of lumbar disk herniation compared to unenhanced VNCa images (all p > .05). Interrater agreement in VNCa imaging was excellent for both, unenhanced and contrast-enhanced CT (κ = 0.84 vs κ = 0.86; p > .05). Moreover, ratings for diagnostic confidence, image quality, and noise differed not significantly between unenhanced and contrast-enhanced VNCa series (all p > .05). Conclusions Color-coded VNCa reconstructions derived from contrast-enhanced dual-energy CT yield similar diagnostic accuracy for the depiction of lumbar disk herniation compared to unenhanced VNCa imaging and therefore may improve opportunistic retrospective lumbar disk herniation assessment, particularly in case of staging CT examinations. Key Points • Color-coded dual-source dual-energy CT virtual noncalcium (VNCa) reconstructions derived from portal venous phase yield similar high diagnostic accuracy for the assessment of lumbar disk herniation compared to unenhanced VNCa CT series (94% vs 95%) with MRI serving as a standard of reference. • Diagnostic confidence, image quality, and noise levels differ not significantly between unenhanced and contrast-enhanced portal venous phase VNCa dual-energy CT series. • Dual-source dual-energy CT might have the potential to improve opportunistic retrospective lumbar disk herniation assessment in CT examinations performed for other indications through reconstruction of VNCa images.

Third-generation dual-source dual-energy CT in pediatric congenital heart disease patients: state-of-the-art

2019 ◽  
Vol 124 (12) ◽  
pp. 1238-1252 ◽  
Author(s):  
Nicolò Schicchi ◽  
Marco Fogante ◽  
Paolo Esposto Pirani ◽  
Giacomo Agliata ◽  
Maria Chiara Basile ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
State Of The Art ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Dual Source

Single- and dual-energy CT pulmonary angiography using second- and third-generation dual-source CT systems: comparison of radiation dose and image quality

2019 ◽  
Vol 29 (9) ◽  
pp. 4603-4612 ◽  
Author(s):  
Lukas Lenga ◽  
Franziska Trapp ◽  
Moritz H. Albrecht ◽  
Julian L. Wichmann ◽  
Addison A. Johnson ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Pulmonary Angiography ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Dual Source Ct ◽  
Ct Pulmonary Angiography ◽  
Dual Source

Virtual unenhanced imaging of the liver with third-generation dual-source dual-energy CT and advanced modeled iterative reconstruction

2016 ◽  
Vol 85 (7) ◽  
pp. 1257-1264 ◽  
Author(s):  
Carlo N. De Cecco ◽  
Giuseppe Muscogiuri ◽  
U. Joseph Schoepf ◽  
Damiano Caruso ◽  
Julian L. Wichmann ◽  
...  
Keyword(s):  
Iterative Reconstruction ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Dual Source ◽  
Virtual Unenhanced

scholarly journals Comparison between Conventional Unenhanced and Virtual Unenhanced Imaging of Hepatopancreaticobiliary System with Third-Generation Dual-Source Dual-Energy CT—An Observational Study

2021 ◽  
Author(s):  
Swathigha Selvaraj ◽  
Niyas N. P. ◽  
Rupa Renganathan ◽  
Rajkumar Ramasamy ◽  
Rinoy Ram Anandan ◽  
...  
Keyword(s):  
Image Quality ◽  
Statistical Significance ◽  
Dual Energy ◽  
Arterial Phase ◽  
Dual Energy Ct ◽  
P Value ◽  
Diagnostic Image Quality ◽  
Third Generation ◽  
Dual Source ◽  
Virtual Unenhanced

Abstract Objectives The aims of our study were to assess the comparability of conventional unenhanced images (CUIs) of hepatopancreaticobiliary system with virtual unenhanced images (VUIs) derived from arterial and portal venous phases acquired in a third-generation, dual-source, dual-energy CT (DECT), and also to assess the best dataset among these VUIs. We also calculated the radiation effective dose (ED) reduction by eliminating noncontrast acquisition. Materials and Methods 60 patients were included in our study. Unenhanced images in single energy and contrast-enhanced images in dual-energy mode were acquired. Arterial virtual unenhanced (AVU) and portal virtual unenhanced (PVU) images were generated and compared with CUI, using both objective and subjective methods. The ED was calculated separately for each phase. Statistical significance between difference in mean attenuation values were analyzed using ANOVA and unpaired student t-test. Results In our study, the difference in mean attenuation of liver, spleen, and pancreas between the three phases—CU, AVU, and PVU—were insignificant with p-value > 0.05. This indicates that the values were comparable. Among the VUI, AVU images were statistically superior in image quality. Elimination of noncontrast CT from triple phase abdominal imaging can achieve an average ED reduction of 39%. Conclusions We conclude that VUI generated in third-generation, dual-source DECT has diagnostic image quality and can replace the CUI in triple-phase studies, with a mean ED reduction by 39%. The VUI obtained from arterial phase is superior to those obtained from portal venous phase.

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