scholarly journals Diagnostic accuracy of color-coded virtual noncalcium reconstructions derived from portal venous phase dual-energy CT in the assessment of lumbar disk herniation

2021 ◽  
Author(s):  
Vitali Koch ◽  
Moritz H. Albrecht ◽  
Leon D. Gruenewald ◽  
Ibrahim Yel ◽  
Katrin Eichler ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Disk Herniation ◽  
Lumbar Disk Herniation ◽  
Portal Venous Phase ◽  
Lumbar Disk ◽  
Contrast Enhanced ◽  
Dual Source ◽  
Venous Phase

Abstract Objectives To investigate the diagnostic accuracy of color-coded contrast-enhanced dual-energy CT virtual noncalcium (VNCa) reconstructions for the assessment of lumbar disk herniation compared to unenhanced VNCa imaging. Methods A total of 91 patients were retrospectively evaluated (65 years ± 16; 43 women) who had undergone third-generation dual-source dual-energy CT and 3.0-T MRI within an examination interval up to 3 weeks between November 2019 and December 2020. Eight weeks after assessing unenhanced color-coded VNCa reconstructions for the presence and degree of lumbar disk herniation, corresponding contrast-enhanced portal venous phase color-coded VNCa reconstructions were independently analyzed by the same five radiologists. MRI series were additionally analyzed by one highly experienced musculoskeletal radiologist and served as reference standard. Results MRI depicted 210 herniated lumbar disks in 91 patients. VNCa reconstructions derived from contrast-enhanced CT scans showed similar high overall sensitivity (93% vs 95%), specificity (94% vs 95%), and accuracy (94% vs 95%) for the assessment of lumbar disk herniation compared to unenhanced VNCa images (all p > .05). Interrater agreement in VNCa imaging was excellent for both, unenhanced and contrast-enhanced CT (κ = 0.84 vs κ = 0.86; p > .05). Moreover, ratings for diagnostic confidence, image quality, and noise differed not significantly between unenhanced and contrast-enhanced VNCa series (all p > .05). Conclusions Color-coded VNCa reconstructions derived from contrast-enhanced dual-energy CT yield similar diagnostic accuracy for the depiction of lumbar disk herniation compared to unenhanced VNCa imaging and therefore may improve opportunistic retrospective lumbar disk herniation assessment, particularly in case of staging CT examinations. Key Points • Color-coded dual-source dual-energy CT virtual noncalcium (VNCa) reconstructions derived from portal venous phase yield similar high diagnostic accuracy for the assessment of lumbar disk herniation compared to unenhanced VNCa CT series (94% vs 95%) with MRI serving as a standard of reference. • Diagnostic confidence, image quality, and noise levels differ not significantly between unenhanced and contrast-enhanced portal venous phase VNCa dual-energy CT series. • Dual-source dual-energy CT might have the potential to improve opportunistic retrospective lumbar disk herniation assessment in CT examinations performed for other indications through reconstruction of VNCa images.

scholarly journals Virtual Noncalcium Dual-Energy CT: Detection of Lumbar Disk Herniation in Comparison with Standard Gray-scale CT

Radiology ◽  
2019 ◽  
Vol 290 (2) ◽  
pp. 446-455 ◽  
Author(s):  
Christian Booz ◽  
Jochen Nöske ◽  
Simon S. Martin ◽  
Moritz H. Albrecht ◽  
Ibrahim Yel ◽  
...  
Keyword(s):  
Dual Energy ◽  
Dual Energy Ct ◽  
Disk Herniation ◽  
Gray Scale ◽  
Lumbar Disk Herniation ◽  
Lumbar Disk

scholarly journals Assessment of thoracic disk herniation by using virtual noncalcium dual-energy CT in comparison with standard grayscale CT

2021 ◽  
Author(s):  
Vitali Koch ◽  
Ibrahim Yel ◽  
Leon D. Grünewald ◽  
Sebastian Beckers ◽  
Iris Burck ◽  
...  
Keyword(s):  
Image Quality ◽  
Diagnostic Accuracy ◽  
Dual Energy ◽  
Spinal Nerve ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Spinal Nerve Root ◽  
Disk Herniation ◽  
Diagnostic Confidence ◽  
Dual Source

Abstract Objectives To determine the diagnostic accuracy of dual-energy CT (DECT) virtual noncalcium (VNCa) reconstructions for assessing thoracic disk herniation compared to standard grayscale CT. Methods In this retrospective study, 87 patients (1131 intervertebral disks; mean age, 66 years; 47 women) who underwent third-generation dual-source DECT and 3.0-T MRI within 3 weeks between November 2016 and April 2020 were included. Five blinded radiologists analyzed standard DECT and color-coded VNCa images after a time interval of 8 weeks for the presence and degree of thoracic disk herniation and spinal nerve root impingement. Consensus reading of independently evaluated MRI series served as the reference standard, assessed by two separate experienced readers. Additionally, image ratings were carried out by using 5-point Likert scales. Results MRI revealed a total of 133 herniated thoracic disks. Color-coded VNCa images yielded higher overall sensitivity (624/665 [94%; 95% CI, 0.89–0.96] vs 485/665 [73%; 95% CI, 0.67–0.80]), specificity (4775/4990 [96%; 95% CI, 0.90–0.98] vs 4066/4990 [82%; 95% CI, 0.79–0.84]), and accuracy (5399/5655 [96%; 95% CI, 0.93–0.98] vs 4551/5655 [81%; 95% CI, 0.74–0.86]) for the assessment of thoracic disk herniation compared to standard CT (all p < .001). Interrater agreement was excellent for VNCa and fair for standard CT (ϰ = 0.82 vs 0.37; p < .001). In addition, VNCa imaging achieved higher scores regarding diagnostic confidence, image quality, and noise compared to standard CT (all p < .001). Conclusions Color-coded VNCa imaging yielded substantially higher diagnostic accuracy and confidence for assessing thoracic disk herniation compared to standard CT. Key Points • Color-coded VNCa reconstructions derived from third-generation dual-source dual-energy CT yielded significantly higher diagnostic accuracy for the assessment of thoracic disk herniation and spinal nerve root impingement compared to standard grayscale CT. • VNCa imaging provided higher diagnostic confidence and image quality at lower noise levels compared to standard grayscale CT. • Color-coded VNCa images may potentially serve as a viable imaging alternative to MRI under circumstances where MRI is unavailable or contraindicated.

Dual-Source Dual-Energy CT Portal Venous Phase Abdominal CT Scans in Large Body Habitus Patients

2018 ◽  
Vol 42 (6) ◽  
pp. 932-936 ◽  
Author(s):  
Vinit Baliyan ◽  
Hamed Kordbacheh ◽  
Jessica Serrao ◽  
Dushyant V. Sahani ◽  
Avinash R. Kambadakone
Keyword(s):  
Large Body ◽  
Dual Energy ◽  
Ct Scans ◽  
Dual Energy Ct ◽  
Abdominal Ct ◽  
Body Habitus ◽  
Portal Venous Phase ◽  
Dual Source ◽  
Venous Phase

Split-Bolus Portal Venous Phase Dual-Energy CT Urography: Protocol Design, Image Quality, and Dose Reduction

2015 ◽  
Vol 205 (5) ◽  
pp. W492-W501 ◽  
Author(s):  
Chiao-Yun Chen ◽  
Jui-Sheng Hsu ◽  
Twei-Shiun Jaw ◽  
Ming-Chen Paul Shih ◽  
Lo-Jeh Lee ◽  
...  
Keyword(s):  
Image Quality ◽  
Dose Reduction ◽  
Dual Energy ◽  
Protocol Design ◽  
Dual Energy Ct ◽  
Ct Urography ◽  
Portal Venous Phase ◽  
Venous Phase

scholarly journals Clinical Value of Energy Spectrum Curves of Dual-energy CT in Evaluating Pathological Grading of Gastric Adenocarcinoma

2019 ◽  
Author(s):  
Zhihua Lu ◽  
Suying Wu ◽  
Jianwei Chen ◽  
Chuan Yan ◽  
Yueming Li
Keyword(s):  
Gastric Cancer ◽  
Energy Spectrum ◽  
Gastric Adenocarcinoma ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Clinical Value ◽  
Pathological Differentiation ◽  
Dual Source ◽  
Venous Phase ◽  
Poorly Differentiated

Abstract Backgroud: Accurate diagnosis of cancer staging and pathological differentiation are critical for the formulation of individualized treatment and prognosis of gastric cancer. It is vital to explore non-invasive preoperative imaging techniques to evaluate the pathological differentiation degree of gastric cancer tissues, and provide better diagnostic basis and decision-making reference for treatment. The purpose of this study was to explore the clinical value of energy spectrum curves of dual-source dual-energy CT in the quantitative evaluation of different pathological grades of gastric adenocarcinoma. Methods: A total of 62 patients with 1 well, 25 moderately and 36 poorly differentiated gastric adenocarcinomas pathologically confirmed by surgery were collected, and they underwent dual-source dual-energy CT plain scanning and enhanced scanning before operation. Dual-Energy software was used to measure the slope of the energy spectrum curves (λ) in arterial and venous phases after image reconstruction. Patients were divided into two groups according to the pathological results, including well and moderately differentiated gastric adenocarcinoma group and poorly differentiated gastric adenocarcinoma group. Data of each group were analyzed by independent sample t-test. The receiver operating characteristic curve was plotted to evaluate the diagnostic efficiency of the corresponding parameters. Results: There were significant differences in λ values of 40-50keV, 40-60keV, 40-80keV, 40-90keV, 40-100keV, 40-120keV, 40-130keV, 40-140keV and 40-150keV energy ranges in venous phase between the well and moderately differentiated group and poorly differentiated group (P<0.05), but no significant differences in λ values of different energy ranges in arterial phase between the two groups (P>0.05). And the area under curve in 40-120keV energy range was the largest in venous phase. K40-120keV =2.69 was selected as the diagnostic threshold with the maximum Youden index, the sensitivity and specificity were 61.1% and 76%, respectively. Conclusion: The energy spectrum curve of dual-energy CT had certain diagnostic value in the quantitative evaluation of pathological grading of gastric adenocarcinoma.

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