MP16-01 ROLE OF FGFR4 IN CLEAR CELL RENAL CARCINOMA AND ITS POTENTIAL AS A NEW THERAPEUTIC TARGET

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Takafumi Narisawa* ◽  
Sei Naito ◽  
Hiromi Ito ◽  
Toshihiko Sakurai ◽  
Osamu Ichiyanagi ◽  
...  
Keyword(s):  
Therapeutic Target ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Cell Renal Carcinoma

Expression and Proliferation-Promoting Role of Lymphoid Enhancer-Binding Factor 1 in Human Clear Cell Renal Carcinoma

2014 ◽  
Vol 32 (7) ◽  
pp. 368-374 ◽  
Author(s):  
Donghao Shang ◽  
Rumei Bi ◽  
Tiandong Han ◽  
Daye Wang ◽  
Ye Tian ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Binding Factor ◽  
Cell Renal Carcinoma

scholarly journals Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma

2009 ◽  
Vol 125 (10) ◽  
pp. 2307-2315 ◽  
Author(s):  
Jean-Laurent Deville ◽  
Catherine Bartoli ◽  
Caroline Berenguer ◽  
Samantha Fernandez-Sauze ◽  
Itidal Kaafarani ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Renal Tumors ◽  
Mrna Levels ◽  
Clear Cell Renal Carcinoma ◽  
Cell Renal Carcinoma

scholarly journals Tissue Based Biomarkers for Metastatic Clear Cell Renal Carcinoma: A Systematic Review

Kidney Cancer ◽  
2020 ◽  
Vol 4 (4) ◽  
pp. 197-210
Author(s):  
Andrew L. Schmidt ◽  
Paul A. Bain ◽  
Bradley A. McGregor
Keyword(s):  
Full Text ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Immune Therapy ◽  
Predictive Biomarkers ◽  
Clear Cell Renal Carcinoma ◽  
Hand Search ◽  
Cell Renal Carcinoma ◽  
Full Text Review

Background: Treatments for metastatic clear cell renal carcinoma (mccRCC) are evolving with multiple targeted and immune therapy drugs currently approved by regulatory agencies as single agents or in combination. Developing predictive biomarkers to determine which patients derive a differential benefit from a particular treatment is an area of ongoing clinical research. Objective: We sought to systematically evaluate the role of tumour tissue-based biomarkers that assist in selection of therapy for mccRCC. Methods: Literature addressing the role of biomarkers in mccRCC was identified through a search of the electronic databases MEDLINE, Embase, and the Web of Science and a hand search of major conference abstracts (from Jan 2010 –Sep 2020). Abstracts were screened to identify papers meriting full-text review. Studies with a comparison arm were included to assess biomarker relevance. A narrative review of studies was performed. Results: The literature search yielded 6784 potentially relevant articles. 133 articles met criteria for full text review, and 10 articles were identified by scanning bibliographies of relevant studies. A total of 33 articles (involving 13 studies) were selected for data extraction and subsequent review. Conclusions: Predictive biomarkers for immediate use in the clinic are lacking, and embedding their evaluation and validation in future clinical trials is needed to refine practice and patient selection.

1651: Molecular Prognostic Modeling Using Protein Expression Profile in Clear Cell Renal Carcinoma

2004 ◽  
Vol 171 (4S) ◽  
pp. 436-436 ◽  
Author(s):  
Hyung L. Kim ◽  
David B. Seligson ◽  
Nicolette Janzen ◽  
Matthew H. Bui ◽  
Robert A. Figlin ◽  
...  
Keyword(s):  
Protein Expression ◽  
Expression Profile ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Protein Expression Profile ◽  
Cell Renal Carcinoma ◽  
Prognostic Modeling
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