The role of hyperuricemia in vascular disorders

2009 ◽  
Vol 21 (2) ◽  
pp. 132-137 ◽  
Author(s):  
N Lawrence Edwards
Keyword(s):  
Vascular Disorders

scholarly journals The role of physical activity in prevention and treatment of peripheral vascular disorders

2020 ◽  
Vol 26 (1) ◽  
pp. 19-27
Author(s):  
Jarosław Pasek ◽  
Agata Stanek ◽  
Grzegorz Cieślar
Keyword(s):  
Physical Activity ◽  
Peripheral Vascular ◽  
Vascular Disorders ◽  
Prevention And Treatment

Foot problems

2017 ◽  
pp. 585-590
Author(s):  
Hylton B. Menz
Keyword(s):  
Quality Of Life ◽  
Older People ◽  
Weight Bearing ◽  
Older Person ◽  
Vascular Disorders ◽  
Foot Problems ◽  
Detrimental Impact

Foot problems affect one in four people aged over 65 years and have a major detrimental impact on mobility and quality of life. With advancing age, the foot undergoes several cutaneous, vascular, neurological, and musculoskeletal changes, all of which may impair this important weight bearing function and predispose the older person to the development of foot symptoms. This chapter provides an overview of the prevalence and impact of foot problems in older people, and briefly discusses the management of common foot problems in older people including skin and nail disorders, vascular disorders, and structural deformities. The important role of footwear in the management of foot problems is also highlighted.

Prevalence of Mild Cognitive Impairment and Its Subtypes among Chinese Older Adults: Role of Vascular Risk Factors

2016 ◽  
Vol 41 (5-6) ◽  
pp. 261-272 ◽  
Author(s):  
Fei Ma ◽  
Tianfeng Wu ◽  
Jiangang Zhao ◽  
Lu Ji ◽  
Aili Song ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Vascular Diseases ◽  
Vascular Risk ◽  
Multivariate Logistic Regression ◽  
Vascular Disorders ◽  
Chinese Older Adults ◽  
Amnestic Mci ◽  
Multiple Domains

Background/Aims: The prevalence of mild cognitive impairment (MCI) and its subtypes among Chinese older adults, and the contribution of vascular risk factors (VRF) and vascular disorders to MCI remain unclear. This study aims to investigate the prevalence of MCI and its different subtypes, and clarify the role of VRF and vascular diseases in the occurrence of MCI. Methods: A random sample of 5,214 nondementia (DSM-IV) individuals aged ≥65 years underwent neuropsychological assessments and clinical examinations. MCI, including amnestic MCI-single domain (aMCI-SD), amnestic MCI-multiple domains (aMCI-MD), nonamnestic MCI-single domain (naMCI-SD), and nonamnestic MCI-multiple domains (naMCI-MD), was defined according to modifications of the Petersen criteria. VRF (smoking, obesity, and diabetes) and vascular disorders (myocardial infarction, atrial fibrillation, stroke, and hypertension) were assessed based on information through self-report and medical records. Data were analyzed using multivariate logistic regression. Results: The prevalence of MCI was 11.33% (95% CI: 8.21-14.43), and that of aMCI-SD, aMCI-MD, naMCI-SD, and naMCI-MD was 4.48% (95% CI: 2.24-6.74), 2.09% (95% CI: 0.80-3.38), 4.22% (95% CI: 1.38-7.08), and 0.53% (95% CI: 0.32-0.75), respectively. The prevalence of MCI is higher in women than in men. Multivariate logistic regression analysis shows that VRF and vascular diseases were significantly related to increase the odds of MCI and its specific subtype. Conclusions: The prevalence of MCI is almost 11% among Chinese older adults. VRF and vascular disorders are associated with MCI, especially naMCI.

Role of Liver Biopsy in the Study of Vascular Disorders of the Liver

2021 ◽  
pp. 3-13
Author(s):  
Valerie Paradis ◽  
Pierre-Emmanuel Rautou
Keyword(s):  
Liver Biopsy ◽  
Vascular Disorders

scholarly journals PET-Based Imaging with 18F-FDG and 18F-NaF to Assess Inflammation and Microcalcification in Atherosclerosis and Other Vascular and Thrombotic Disorders

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2234
Author(s):  
William Y. Raynor ◽  
Peter Sang Uk Park ◽  
Austin J. Borja ◽  
Yusha Sun ◽  
Thomas J. Werner ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Disease Burden ◽  
Early Stage ◽  
Vascular Diseases ◽  
Early Assessment ◽  
Vascular Disorders ◽  
Atherosclerosis Progression ◽  
Positron Emission ◽  
Potential Applications

Positron emission tomography (PET) imaging with 18F-fluorodeoxyglucose (FDG) represents a method of detecting and characterizing arterial wall inflammation, with potential applications in the early assessment of vascular disorders such as atherosclerosis. By portraying early-stage molecular changes, FDG-PET findings have previously been shown to correlate with atherosclerosis progression. In addition, recent studies have suggested that microcalcification revealed by 18F-sodium fluoride (NaF) may be more sensitive at detecting atherogenic changes compared to FDG-PET. In this review, we summarize the roles of FDG and NaF in the assessment of atherosclerosis and discuss the role of global assessment in quantification of the vascular disease burden. Furthermore, we will review the emerging applications of FDG-PET in various vascular disorders, including pulmonary embolism, as well as inflammatory and infectious vascular diseases.

scholarly journals Role of vascular disorders in lung injury in patients with rheumatoid arthritis

2016 ◽  
Vol 15 (3) ◽  
pp. 15-23 ◽  
Author(s):  
I. I. Nesterovich ◽  
K. V. Nochevnaya ◽  
Y. D. Rabik ◽  
A. A. Speranskaya ◽  
V. P. Zolotnitskaya ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Computed Tomography ◽  
Lung Injury ◽  
Pulmonary Function Tests ◽  
Photon Emission ◽  
Diagnostic Methods ◽  
Control Group ◽  
Emission Computed Tomography ◽  
Vascular Disorders

Introduction. The incidence of respiratory system involvement in patients with rheumatoid arthritis (RA) has currently increased; thereby new diagnostic methods have been developed actively. Meanwhile role of vascular disorders in pathogenesis of lung injury is almost unknown and single-photon emission computed tomography (SPECT) isn't used as method of lung assessment in RA. The detector of endothelial glycocalyx damage syndecan-1 is little known but potentially perspective serum marker of lung injury in RA. Objective. The purpose of the study was to investigate the role of vascular disorders in lung injury in patients with RA. Materials and methods. 61 patients with RA without comorbid lung diseases were enrolled in the study. Control group consisted of 26 healthy persons. Patients underwent survey and physical examination, high-resolution computed tomography (HRCT) and SPECT of the lungs and pulmonary function tests (PFTs). Also serum levels of rheumatoid factor (RF), anti-cyclic citrullinated peptide antibodies (ACCP) and syndecan-1 were measured. Results. All patients developed microcirculation impairment on SPECT. Vascular disorders were according to changes of lung structure detected by HRCT (r = 0.434; p = 0.044). Areas of hypoperfusion matched with ground glass opacities, lung fibrosis, branching linear structures and airway obstruction on HRCT-SPECT fusion scans. Syndecan-1 level was higher in patients with RA compared with healthy controls (р = 0.019). Conclusion. Vascular disorders are important in pathogenesis of lung injury in RA, and SPECT has high sensitivity in lung assessment. Perfusion impairment in lungs correlates with syndecan-1 level, thus syndecan-1 could be used as marker of lung injury in RA thereafter.

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