Long-term Minimum 15-Year Follow-up After Lateral Discoid Meniscus Rim Preservation Surgery in Children and Adolescents

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Laura A.B. Lins ◽  
Aliya G. Feroe ◽  
Brian Yang ◽  
Kathryn A. Williams ◽  
Sophia D. Kocher ◽  
...  
2020 ◽  
Vol 33 (11) ◽  
pp. 1431-1441
Author(s):  
Montserrat Negre Busó ◽  
Amparo García Burillo ◽  
Marc Simó Perdigó ◽  
Pere Galofré Mora ◽  
Maria Boronat de Ferrater ◽  
...  

AbstractObjectivesThe aims were to analyze the clinical features, response to treatment, prognostic factors and long-term follow-up of children and adolescents with differentiated thyroid carcinoma (DTC).MethodsEighty patients with DTC were studied retrospectively. All underwent total or near-total thyroidectomy, and in 75 cases, ablative iodine therapy was recommended. Patients were assessed periodically by tests for serum thyroglobulin levels and whole-body iodine scans. Age, gender, initial clinical presentation, histology, tumor stage, postoperative complications, radioiodine treatment protocol, treatment response, thyroglobulin (Tg), recurrence and long-term disease progression were evaluated.ResultsSeventy patients completed >2 years of follow-up (23 males, 47 females; median age: 14 years; range: 3–18 years). Sixty-two patients showed papillary DTC and eight, follicular DTC. Sixty-five percent presented nodal metastasis and 16%, pulmonary metastasis at diagnosis. Six months after first radioiodine treatment, 36.2% of patients were free of disease. Seven recurrences were documented. At the end of follow-up, overall survival was 100%, and 87.2% of patients were in complete remission. Nine patients had persistent disease. We found a significant association between stage 4 and persistent disease. Hundred percent of patients with negative Tg values at 6 months posttreatment were documented free of disease at the end of the follow-up. The analysis of disease-free survival based on radioiodine treatment protocols used showed no statistically significant differences.ConclusionsDTC in children and adolescents is frequently associated with presence of advanced disease at diagnosis. Despite this, complete remission was documented after treatment in most cases, with a good prognosis in the long-term follow-up. Negative posttreatment thyroglobulin and stage 4 at diagnosis were significant prognostic variables.


PEDIATRICS ◽  
2007 ◽  
Vol 119 (5) ◽  
pp. e1116-e1120 ◽  
Author(s):  
M. W. Kline ◽  
S. Rugina ◽  
M. Ilie ◽  
R. F. Matusa ◽  
A.-M. Schweitzer ◽  
...  

1996 ◽  
Vol 253 (3) ◽  
pp. 158-166 ◽  
Author(s):  
J. Kiefer ◽  
V. Gall ◽  
C. Desloovere ◽  
R. Knecht ◽  
A. Mikowski ◽  
...  

2010 ◽  
Vol 105 (8) ◽  
pp. 1884-1892 ◽  
Author(s):  
Zhao-Shen Li ◽  
Wei Wang ◽  
Zhuan Liao ◽  
Duo-Wu Zou ◽  
Zhen-Dong Jin ◽  
...  

1998 ◽  
Vol 83 (8) ◽  
pp. 2777-2780 ◽  
Author(s):  
Annamaria Colao ◽  
Sandro Loche ◽  
Marco Cappa ◽  
Antonella Di Sarno ◽  
Maria Luisa Landi ◽  
...  

2020 ◽  
Vol 9 (6) ◽  
pp. 1912 ◽  
Author(s):  
Stefanie Truttmann ◽  
Julia Philipp ◽  
Michael Zeiler ◽  
Claudia Franta ◽  
Tanja Wittek ◽  
...  

Interventions for main carers of adult patients with anorexia nervosa (AN) can reduce the caregiving burden and increase caregiver skills. However, the effectiveness and feasibility for carers of adolescent patients, the optimal form of the intervention and long-term outcomes are largely unknown. We evaluated the efficacy and feasibility of the “Supporting Carers of Children and Adolescents with Eating Disorders in Austria” (SUCCEAT) workshop vs. online intervention. Main caregivers (parents) of adolescent patients with AN were randomly allocated to a workshop (n = 50) or online version (n = 50). Participants were compared to a non-randomised comparison group (n = 49) receiving multi-family or systemic family therapy. Primary (General Health Questionnaire) and secondary outcomes were obtained at baseline, three-month and 12-month follow-up. Adherence was high for workshop and online participants (6.2 and 6.7 sessions completed out of 8). Intention-to-treat analyses revealed significant pre–post reductions in the primary outcome for the workshop (d = 0.87 (95%conficence interval (CI): 0.48; 1.26)) and online (d = 0.65 (95%CI: 0.31; 0.98)) intervention that were sustained at the 12-month follow-up. There was no significant group difference (p = 0.473). Parental psychopathology and burden decreased and caregiver skills increased in all groups; the improvement of caregiver skills was significantly higher in SUCCEAT participants than in the comparison group. Online interventions for parents of adolescents with AN were equally effective as workshops. The improvements remained stable over time.


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