Corticosteroid therapy for patients in septic shock: Some progress in a difficult decision

2011 ◽  
Vol 39 (3) ◽  
pp. 571-574 ◽  
Author(s):  
Charles L. Sprung ◽  
Mayer Brezis ◽  
Serge Goodman ◽  
Yoram G. Weiss
Keyword(s):  
Septic Shock ◽  
Corticosteroid Therapy ◽  
Difficult Decision

Corticosteroid therapy in hemorrhagic and septic shock in puppies

1980 ◽  
Vol 15 (6) ◽  
pp. 790-796 ◽  
Author(s):  
Robert H. Connors ◽  
Arnold G. Coran ◽  
John R. Wesley ◽  
Robert A. Drongowski ◽  
William H. Weintraub
Keyword(s):  
Septic Shock ◽  
Corticosteroid Therapy

scholarly journals Early initiation of low-dose corticosteroid therapy in the management of septic shock: a retrospective observational study

Critical Care ◽  
2012 ◽  
Vol 16 (1) ◽  
pp. R3 ◽  
Author(s):  
Hey Yun Park ◽  
Gee Young Suh ◽  
Jae-Uk Song ◽  
Hongseok Yoo ◽  
Ik Joon Jo ◽  
...  
Keyword(s):  
Septic Shock ◽  
Observational Study ◽  
Corticosteroid Therapy ◽  
Low Dose ◽  
Early Initiation ◽  
Retrospective Observational Study ◽  
Dose Corticosteroid

Corticosteroid Therapy for Septic Shock and Pediatric ARDS

2018 ◽  
pp. 271-284
Author(s):  
Lauren Jacobs ◽  
Hector Wong ◽  
Kusum Menon
Keyword(s):  
Septic Shock ◽  
Corticosteroid Therapy

Corticosteroid Therapy for Severe Sepsis and Septic Shock

JAMA ◽  
2009 ◽  
Vol 302 (15) ◽  
pp. 1643 ◽  
Author(s):  
Peter C. Minneci
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Corticosteroid Therapy ◽  
Sepsis And Septic Shock

PERSISTENTLY BLUNTED ACTH RESPONSE IN PATIENTS WITH SEPTIC SHOCK AFTER 7 DAYS OF CORTICOSTEROID THERAPY

CHEST Journal ◽  
2007 ◽  
Vol 132 (4) ◽  
pp. 554B
Author(s):  
Lonny Yarmus ◽  
Michelle Guzowski ◽  
Richard Riker ◽  
Daniel Spratt
Keyword(s):  
Septic Shock ◽  
Corticosteroid Therapy

34: The Effect of Early Corticosteroid Therapy on Outcomes in Children With Septic Shock

2020 ◽  
Vol 49 (1) ◽  
pp. 18-18
Author(s):  
Nicole Kamps ◽  
Russell Banks ◽  
Ron Reeder ◽  
Pelin Cengiz ◽  
Jerry Zimmerman
Keyword(s):  
Septic Shock ◽  
Corticosteroid Therapy

scholarly journals Corticosteroids for pediatric septic shock patients

2019 ◽  
Vol 59 (2) ◽  
pp. 67-71
Author(s):  
Irene Yuniar ◽  
Vembricha Nindya Manusita ◽  
Sonya Leonardy Low
Keyword(s):  
Septic Shock ◽  
Mortality Rate ◽  
Corticosteroid Therapy ◽  
Pediatric Intensive Care ◽  
Median Number ◽  
Cross Sectional Study ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Cross Sectional ◽  
Almost All

Background Septic shock remains a major cause of mortality and admission to the pediatric intensive care unit (PICU) in children. Management includes adequate fluid resuscitation, followed by catecholamine infusion, if needed. Corticosteroid therapy is advised for catecholamine-refractory shock, although this practice is controversial, as it was not beneficial in other studies. Objective To assess corticosteroid use in pediatric septic shock patients in Cipto Mangunkusumo Hospital. Methods This cross-sectional study included all patients aged 1 month-18 years with a diagnosis of septic shock during the study period of January 2014 to July 2018 admitted in PICU Dr. Cipto Mangunkuskumo Hospital, Jakarta. Data obtained from medical records were, age, sex, immunology status, port d’entrée of sepsis, inotropic and vasopressor usage, mechanical ventilation, corticosteroid type, hospital length of stay (LOS), and mortality outcome. Results Of 217 children with septic shock, 12 patients (5.5%) received corticosteroid therapy. The most common corticosteroid given was hydrocortisone (80%), with a 2 mg/kg BW loading dose, followed by a continuous infusion dose of 2-50 mg/kg BW/day. Almost all patients (11/12) received corticosteroid therapy until they died. Median duration of corticosteroid use was 2 (range 1-7) days, median number of inotropes and vasopressors used was 3 (range 2-4) agents, median LOS was 3 (range 1-9) days, and mortality rate was 100%. Conclusion A small proportion of pediatric septic shock patients received corticosteroid therapy. Their mortality rate was 100%. Further clinical study is needed to evaluate the benefit of corticosteroid therapy in pediatric septic shock patients.

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