Prognostic significance of fascin-1 and E-cadherin expression in laryngeal squamous cell carcinoma

2010 ◽  
Vol 19 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Jian Zou ◽  
Hui Yang ◽  
Fei Chen ◽  
Houyu Zhao ◽  
Pin Lin ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance ◽  
E Cadherin

scholarly journals The prognostic significance of E-cadherin expression in laryngeal squamous-cell carcinoma: a systematic review

2018 ◽  
Vol 38 (6) ◽  
pp. 504-510
Author(s):  
M. Re ◽  
F. M. Gioacchini ◽  
A. Scarpa ◽  
C. Cassandro ◽  
M. Tulli ◽  
...  
Keyword(s):  
Systematic Review ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance ◽  
E Cadherin

Reduced E-cadherin expression is associated with lymph node metastases in laryngeal squamous cell carcinoma

2012 ◽  
Vol 39 (2) ◽  
pp. 186-192 ◽  
Author(s):  
Jing-jia Li ◽  
Ge-hua Zhang ◽  
Xin-ming Yang ◽  
Shi-sheng Li ◽  
Xian Liu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymph Node Metastases ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Node Metastases ◽  
E Cadherin

scholarly journals Prognostic Significance of Peripheral T‐Cell Subsets in Laryngeal Squamous Cell Carcinoma

2019 ◽  
Vol 4 (5) ◽  
pp. 513-519
Author(s):  
Filippo Marchi ◽  
Francesco Missale ◽  
Fabiola Incandela ◽  
Marta Filauro ◽  
Francesco Mazzola ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
T Cell ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance ◽  
T Cell Subsets

The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma

2015 ◽  
Vol 126 (4) ◽  
pp. E148-E155 ◽  
Author(s):  
Antonio Greco ◽  
Armando De Virgilio ◽  
Maria Ida Rizzo ◽  
Fabio Pandolfi ◽  
Davide Rosati ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Role ◽  
E Cadherin

scholarly journals Prognostic significance of methyl-p-hydroxy-phenyllactate-esterase activity in laryngeal squamous cell carcinoma

1998 ◽  
Vol 77 (8) ◽  
pp. 1253-1259 ◽  
Author(s):  
M Maurizi ◽  
G Ferrandina ◽  
G Almadori ◽  
G Scambia ◽  
G Cadoni ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Esterase Activity ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance

Lack of Expression of Galectin-3 Is Associated With a Poor Outcome in Node-Negative Patients With Laryngeal Squamous-Cell Carcinoma

2002 ◽  
Vol 20 (18) ◽  
pp. 3850-3856 ◽  
Author(s):  
Mauro Piantelli ◽  
Stefano Iacobelli ◽  
Giovanni Almadori ◽  
Manuela Iezzi ◽  
Nicola Tinari ◽  
...  
Keyword(s):  
Overall Survival ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Univariate Analysis ◽  
Prognostic Significance ◽  
Node Negative ◽  
Increased Risk ◽  
Galectin 3

PURPOSE: Galectin-3 is a pleiotropic carbohydrate-binding protein participating in a variety of normal and pathologic processes, including cancer progression. This study was aimed at evaluating the prognostic value of galectin-3 expression in node-negative laryngeal squamous-cell carcinoma (SCC). PATIENTS AND METHODS: Galectin-3 expression was analyzed by immunohistochemistry using M3/38 monoclonal antibody, in a single-institution series of 73 node-negative laryngeal SCC patients (median follow-up, 52 months; range, 2 to 90 months). RESULTS: Forty-two (57.5%) of 73 patients expressed galectin-3. Galectin-3 expression was positively associated with tumor keratinization and histologic grade. A significant correlation was found between galectin-3 tumor positivity and longer relapse-free and overall survival. In univariate analysis, high-grade (grade 3 or 4) tumors, nonkeratinizing tumors, and galectin-3–negative tumors showed a significantly increased risk of relapse and death. In multivariate analysis, only galectin-3 expression retained an independent prognostic significance for both relapse-free and overall survival. CONCLUSION: We conclude that the absence of galectin-3 expression is an independent negative prognostic marker in laryngeal SCC patients. Thus, histochemical detection of galectin-3 in these tumors could be useful for the selection of node-negative patients with potentially unfavorable outcomes, to establish adjuvant therapy protocols.

Prognostic significance of the Ca2+ binding protein S100A2 in laryngeal squamous-cell carcinoma

2000 ◽  
Vol 89 (4) ◽  
pp. 345-349 ◽  
Author(s):  
Libero Lauriola ◽  
Fabrizio Michetti ◽  
Nicola Maggiano ◽  
Jacopo Galli ◽  
Gabriella Cadoni ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Binding Protein ◽  
Prognostic Significance

Prognostic significance of Ki-67 expression for patients with laryngeal squamous cell carcinoma primarily treated by total laryngectomy

2003 ◽  
Vol 261 (7) ◽  
pp. 376-380 ◽  
Author(s):  
Mustafa Fuat Acikalin ◽  
Ülkü Öner ◽  
Nilüfer Tel ◽  
Özgül Paşaoğlu ◽  
Hamdi Çakli ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Total Laryngectomy ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance ◽  
Ki 67

scholarly journals Prognostic significance of artemin and GFRα1 expression in laryngeal squamous cell carcinoma

2014 ◽  
Vol 8 (3) ◽  
pp. 818-822 ◽  
Author(s):  
CHAOBING GAO ◽  
XINGWANG CHENG ◽  
XIAOHONG LI ◽  
BUSHENG TONG ◽  
KAILE WU ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Prognostic Significance
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